butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Jaster R et al. | Inhibition of proliferation but not erythroid differentiation of J2E cells by rapamycin. | 1996 | Biochem. Pharmacol. | pmid:8645341 |
Kawasaki N et al. | Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis. | 1996 | Arch. Biochem. Biophys. | pmid:8645006 |
Tilbrook PA et al. | Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin. | 1996 | J. Biol. Chem. | pmid:8631947 |
Chang ST and Yung BY | Potentiation of sodium butyrate-induced apoptosis by vanadate in human promyelocytic leukemia cell line HL-60. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8630006 |
Turin F et al. | n-Butyrate, a cell cycle blocker, inhibits early amplification of duck hepatitis B virus covalently closed circular DNA after in vitro infection of duck hepatocytes. | 1996 | J. Virol. | pmid:8627742 |
Keusch GT et al. | Comparison of the effects of Shiga-like toxin 1 on cytokine- and butyrate-treated human umbilical and saphenous vein endothelial cells. | 1996 | J. Infect. Dis. | pmid:8627068 |
Jaskiewicz J et al. | Catabolism of isobutyrate by colonocytes. | 1996 | Arch. Biochem. Biophys. | pmid:8619613 |
Sharma HW et al. | Differentiation of immortal cells inhibits telomerase activity. | 1995 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8618897 |
Musk SR et al. | Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. | 1995 | Nutr Cancer | pmid:8610048 |
Miller G et al. | Antibodies to butyrate-inducible antigens of Kaposi's sarcoma-associated herpesvirus in patients with HIV-1 infection. | 1996 | N. Engl. J. Med. | pmid:8609946 |
Le Roux F et al. | Epstein-Barr virus (EBV) EB1/Zta protein provided in trans and competent for the activation of productive cycle genes does not activate the BZLF1 gene in the EBV genome. | 1996 | J. Gen. Virol. | pmid:8601788 |
Buquet-Fagot C et al. | Sodium butyrate inhibits the phosphorylation of the retinoblastoma gene product in mouse fibroblasts by a transcription-dependent mechanism. | 1996 | J. Cell. Physiol. | pmid:8600167 |
Bridges EG et al. | 3'-Azido-3'-deoxythymidine inhibits erythroid-specific transcription factors in human erythroid K562 leukemia cells. | 1996 Jan-Feb | Eur. J. Haematol. | pmid:8599995 |
Krupitza G et al. | Genes related to growth and invasiveness are repressed by sodium butyrate in ovarian carcinoma cells. | 1996 | Br. J. Cancer | pmid:8595156 |
Pagés JC et al. | Activation of Moloney murine leukemia virus LTR enhances the titer of recombinant retrovirus in psi CRIP packaging cells. | 1995 | Gene Ther. | pmid:8593605 |
Muto N et al. | Hinokitiol induces differentiation of teratocarcinoma F9 cells. | 1995 | Biol. Pharm. Bull. | pmid:8593483 |
Iwai SA et al. | The kinetics of induction of Hox1.6 and C-jun mRNA during three different ways of inducing differentiation in teratocarcinoma F9 cells. | 1995 | In Vitro Cell. Dev. Biol. Anim. | pmid:8589890 |
Justus AC et al. | Heparan-dependent endothelial antithrombin binding is increased by butyrate. | 1995 | Thromb. Res. | pmid:8588189 |
Pallauf J et al. | Influence of cAMP-effector-agonists on the synthesis of metallothionein in rat primary hepatocytes. | 1995 | Z Ernahrungswiss | pmid:8585245 |
Clausen MR | Butyrate and colorectal cancer in animals and in humans (mini-symposium: butyrate and colorectal cancer). | 1995 | Eur. J. Cancer Prev. | pmid:8580784 |
Yu X et al. | Kinetic analysis of dynamic 13C NMR spectra: metabolic flux, regulation, and compartmentation in hearts. | 1995 | Biophys. J. | pmid:8580353 |
Laubach VE et al. | High-level expression of human inducible nitric oxide synthase in Chinese hamster ovary cells and characterization of the purified enzyme. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8579595 |
Stringer RE et al. | Sodium butyrate delays neutrophil apoptosis: role of protein biosynthesis in neutrophil survival. | 1996 | Br. J. Haematol. | pmid:8562392 |
Bartram HP et al. | Effects of deoxycholic acid and butyrate on mucosal prostaglandin E2 release and cell proliferation in the human sigmoid colon. | 1995 May-Jun | JPEN J Parenter Enteral Nutr | pmid:8551644 |
Calsamiglia S et al. | Effects of ruminal versus duodenal dosing of fish meal on ruminal fermentation and milk composition. | 1995 | J. Dairy Sci. | pmid:8550909 |
Bhatia U et al. | Induction of cell differentiation potentiates apoptosis triggered by prior exposure to DNA-damaging drugs. | 1995 | Cell Growth Differ. | pmid:8547222 |
Nagasawa T et al. | Differences in cellular transport of tri-iodothyronine and thyroxine: cell cycle-dependent alteration of tri-iodothyronine uptake. | 1995 | J. Endocrinol. | pmid:8543918 |
Zhai Y et al. | Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy. | 1996 | J. Immunol. | pmid:8543823 |
Nuydens R et al. | Sodium butyrate induces aberrant tau phosphorylation and programmed cell death in human neuroblastoma cells. | 1995 | Brain Res. | pmid:8542327 |
Newmark HL and Young CW | Butyrate and phenylacetate as differentiating agents: practical problems and opportunities. | 1995 | J. Cell. Biochem. Suppl. | pmid:8538206 |
Cremer JE et al. | Rapid blood-brain transport and metabolism of butyrate and pyruvate in the rat after portocaval anastomosis [proceedings]. | 1977 | J. Physiol. (Lond.) | pmid:853427 |
Sasaki Y et al. | Effects of glucose and butyrate on insulin release from perifused fragments of sheep pancreas. | 1977 | J. Endocrinol. | pmid:853270 |
Conway RM et al. | Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line. | 1995 | Oncol. Res. | pmid:8527863 |
Olsen JC and Sechelski J | Use of sodium butyrate to enhance production of retroviral vectors expressing CFTR cDNA. | 1995 | Hum. Gene Ther. | pmid:8527478 |
Kvale D and Brandtzaeg P | Butyrate differentially affects constitutive and cytokine-induced expression of HLA molecules, secretory component (SC), and ICAM-1 in a colonic epithelial cell line (HT-29, clone m3). | 1995 | Adv. Exp. Med. Biol. | pmid:8525902 |
Brill S et al. | Maturation-dependent changes in the regulation of liver-specific gene expression in embryonal versus adult primary liver cultures. | 1995 | Differentiation | pmid:8522072 |
Oda S et al. | Insulin and glucagon secretion in goats (Capra hircus Linnaeus) exposed to cold. | 1995 | Comp. Biochem. Physiol. C, Pharmacol. Toxicol. Endocrinol. | pmid:8521249 |
Afonso RodrÃguez JJ et al. | [Cytometric study of colonic tumors in a model of experimental colonic cancer. Impact of the diet]. | 1995 Sep-Oct | Nutr Hosp | pmid:8519854 |
Petit JM et al. | mdr 1 gene-expression and villin synthesis in a colon cancer cell line differentiated by sodium butyrate. | 1993 Mar-Apr | Anticancer Res. | pmid:8517666 |
Khochbin S and Wolffe AP | Developmental regulation and butyrate-inducible transcription of the Xenopus histone H1(0) promoter. | 1993 | Gene | pmid:8514185 |
Desai TK et al. | Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate. | 1993 | Cancer Lett. | pmid:8513444 |
Zon LI et al. | Expression of mRNA for the GATA-binding proteins in human eosinophils and basophils: potential role in gene transcription. | 1993 | Blood | pmid:8507862 |
Souleimani A and Asselin C | Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8503924 |
Ford R et al. | Modulation of SPARC expression during butyrate-induced terminal differentiation of cultured human keratinocytes: regulation via a TGF-beta-dependent pathway. | 1993 | Exp. Cell Res. | pmid:8500547 |
Yanagi S et al. | Sodium butyrate inhibits the enhancing effect of high fat diet on mammary tumorigenesis. | 1993 Jul-Aug | Oncology | pmid:8497370 |
Sjöholm A | Sodium butyrate inhibits rat insulinoma cell proliferation without affecting the cellular insulin content or insulin release. | 1993 | Anticancer Drugs | pmid:8490204 |
Kight CE and Fleming SE | Nutrient oxidation by rat intestinal epithelial cells is concentration dependent. | 1993 | J. Nutr. | pmid:8487099 |
Huhtanen P et al. | Effect of increasing ruminal butyrate on milk yield and blood constituents in dairy cows fed a grass silage-based diet. | 1993 | J. Dairy Sci. | pmid:8486840 |
Altenkirch H et al. | Experimental studies on hydrocarbon neuropathies induced by methyl-ethyl-ketone (MEK). | 1978 | J. Neurol. | pmid:84859 |
Hume ID et al. | Acetate, butyrate and proline uptake in the caecum and colon of prairie voles (Microtus ochrogaster). | 1993 | J. Exp. Biol. | pmid:8478602 |
Van Lier JB et al. | Effects of acetate, propionate, and butyrate on the thermophilic anaerobic degradation of propionate by methanogenic sludge and defined cultures. | 1993 | Appl. Environ. Microbiol. | pmid:8476278 |
Lea MA et al. | Butyramide and monobutyrin: growth inhibitory and differentiating agents. | 1993 Jan-Feb | Anticancer Res. | pmid:8476205 |
Gill RK and Christakos S | Identification of sequence elements in mouse calbindin-D28k gene that confer 1,25-dihydroxyvitamin D3- and butyrate-inducible responses. | 1993 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8464915 |
Iwai SA et al. | Changes in Hox1.6, c-jun, and Oct-3 gene expressions are associated with teratocarcinoma F9 cell differentiation in three different ways of induction. | 1993 | Exp. Cell Res. | pmid:8453995 |
Utesch D et al. | Effects of sodium butyrate on DNA content, glutathione S-transferase activities, cell morphology and growth characteristics of rat liver nonparenchymal epithelial cells in vitro. | 1993 | Carcinogenesis | pmid:8453722 |
Saito H et al. | Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor. | 1993 | Int. Arch. Allergy Immunol. | pmid:8453311 |
Gálfi P et al. | Influences of extracellular matrix components on the growth and differentiation of ruminal epithelial cells in primary culture. | 1993 | Res. Vet. Sci. | pmid:8434137 |
Gerharz CD et al. | Modulation of invasive potential in different clonal subpopulations of a rat rhabdomyosarcoma cell line (BA-HAN-1) by differentiation induction. | 1993 | Clin. Exp. Metastasis | pmid:8422707 |
Blau CA et al. | Fetal hemoglobin induction with butyric acid: efficacy and toxicity. | 1993 | Blood | pmid:8422469 |
Herz F | Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. | 1993 | Biochim. Biophys. Acta | pmid:8422435 |
Sommerville J et al. | Histone H4 acetylation and transcription in amphibian chromatin. | 1993 | J. Cell Biol. | pmid:8421048 |
Dohi T et al. | Induction of the fundic mucosa-specific glycolipid with dimethylformamide in gastric-cancer cell lines. | 1993 | Int. J. Cancer | pmid:8416198 |
Diener M et al. | Effect of short-chain fatty acids on cell volume and intracellular pH in rat distal colon. | 1993 | Pflugers Arch. | pmid:8414909 |
Wischmeyer P et al. | Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study. | 1993 | Mayo Clin. Proc. | pmid:8412364 |
Polack A et al. | Regulatory elements in the immunoglobulin kappa locus induce c-myc activation and the promoter shift in Burkitt's lymphoma cells. | 1993 | EMBO J. | pmid:8404859 |
Salvador V et al. | Sugar composition of dietary fibre and short-chain fatty acid production during in vitro fermentation by human bacteria. | 1993 | Br. J. Nutr. | pmid:8399101 |
Hague A et al. | Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. | 1993 | Int. J. Cancer | pmid:8397167 |
Telfer JF and Green CD | Placental alkaline phosphatase activity is inversely related to cell growth rate in HeLaS3 cervical cancer cells. | 1993 | FEBS Lett. | pmid:8396040 |
Rius C et al. | Differential modulation of the expression of the intermediate filament proteins vimentin and nuclear lamins A and C by differentiation inducers in human myeloid leukemia (U-937, HL-60) cells. | 1993 | Exp. Cell Res. | pmid:8395394 |
Khan MZ et al. | Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP. | 1993 | Ann. Oncol. | pmid:8394737 |
Sakamoto K et al. | Relative mitogenic activities of wild-type and retinoblastoma binding-defective SV40 T antigens in serum-deprived and senescent human diploid fibroblasts. | 1993 | Oncogene | pmid:8390037 |
Wind JC et al. | Stimulation of calcitonin/CGRP-I and CGRP-II gene expression by dibutyryl cAMP in a human medullary thyroid carcinoma (TT) cell line. | 1993 | Mol. Cell. Endocrinol. | pmid:8386116 |
Datti A and Dennis JW | Regulation of UDP-GlcNAc:Gal beta 1-3GalNAc-R beta 1-6-N-acetylglucosaminyltransferase (GlcNAc to GalNAc) in Chinese hamster ovary cells. | 1993 | J. Biol. Chem. | pmid:8383671 |
Gaudet SJ et al. | Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells. | 1993 | Neurochem. Int. | pmid:8382984 |
Darcy-Vrillon B et al. | Metabolic characteristics of pig colonocytes after adaptation to a high fiber diet. | 1993 | J. Nutr. | pmid:8381478 |
Heruth DP et al. | Sodium butyrate causes an increase in the block to transcriptional elongation in the c-myc gene in SW837 rectal carcinoma cells. | 1993 | J. Biol. Chem. | pmid:8376401 |
Griner RD et al. | The role of short chain fatty acid substrates in aerobic and glycolytic metabolism in primary cultures of renal proximal tubule cells. | 1993 | In Vitro Cell. Dev. Biol. Anim. | pmid:8376317 |
Nishina Y et al. | The induction of jun genes during the reversible changes induced with sodium butyrate on the differentiation of F9 cells. | 1993 | Exp. Cell Res. | pmid:8375477 |
Barnard JA and Warwick G | Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells. | 1993 | Cell Growth Differ. | pmid:8373733 |
Laughlin MA et al. | Sodium butyrate treatment of cells latently infected with HIV-1 results in the expression of unspliced viral RNA. | 1993 | Virology | pmid:8372431 |
Schmidt JE and Ahring BK | Effects of hydrogen and formate on the degradation of propionate and butyrate in thermophilic granules from an upflow anaerobic sludge blanket reactor. | 1993 | Appl. Environ. Microbiol. | pmid:8368842 |
Wiekowski M et al. | Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. | 1993 | Dev. Biol. | pmid:8365573 |
Calabresse C et al. | Butyric acid and its monosaccharide ester induce apoptosis in the HL-60 cell line. | 1993 | Biochem. Biophys. Res. Commun. | pmid:8363611 |
Mollinedo F et al. | Differences in expression of transcription factor AP-1 in human promyelocytic HL-60 cells during differentiation towards macrophages versus granulocytes. | 1993 | Biochem. J. | pmid:8363564 |
Taggart M and Wray S | Simultaneous measurement of intracellular pH and contraction in uterine smooth muscle. | 1993 | Pflugers Arch. | pmid:8351202 |
Murray NR et al. | Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. | 1993 | J. Biol. Chem. | pmid:8340409 |
Cremer JE et al. | The influence of portocaval anastomosis on the metabolism of labelled octanoate, butyrate and leucine in rat brain. | 1977 | J. Neurochem. | pmid:833594 |
Komatsu N et al. | Establishment and characterization of an erythropoietin-dependent subline, UT-7/Epo, derived from human leukemia cell line, UT-7. | 1993 | Blood | pmid:8329702 |
Souleimani A and Asselin C | Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2. | 1993 | FEBS Lett. | pmid:8325387 |
Bartram HP et al. | Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH. | 1993 | Cancer Res. | pmid:8324739 |
Chapman MA et al. | Butyrate oxidation is impaired in the colonic mucosa of sufferers of quiescent ulcerative colitis. | 1994 | Gut | pmid:8307454 |
Yabushita H and Sartorelli AC | Effects of sodium butyrate, dimethylsulfoxide and dibutyryl cAMP on the poorly differentiated ovarian adenocarcinoma cell line AMOC-2. | 1993 | Oncol. Res. | pmid:8305743 |
Steinhart AH et al. | Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas. | 1994 | Am. J. Gastroenterol. | pmid:8304299 |
Fernandez-Mejia C and Davidson MB | Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells. | 1993 | Pancreas | pmid:8302795 |
Dong QG et al. | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. | 1993 | Anticancer Drugs | pmid:8298162 |
Carraro S et al. | [Influence of sodium butyrate intake on murine colonic carcinogenesis]. | 1993 | Medicina (B Aires) | pmid:8295530 |
Iwami K and Moriyama T | Effects of short chain fatty acid, sodium butyrate, on osteoblastic cells and osteoclastic cells. | 1993 | Int. J. Biochem. | pmid:8288032 |
Roediger WE et al. | Sulphide impairment of substrate oxidation in rat colonocytes: a biochemical basis for ulcerative colitis? | 1993 | Clin. Sci. | pmid:8287651 |
Sperker B et al. | The expression of human plasma cholesteryl-ester-transfer protein in HepG2 cells is induced by sodium butyrate. Quantification of low mRNA levels by polymerase chain reaction. | 1993 | Eur. J. Biochem. | pmid:8281947 |
Hague A et al. | Escape from negative regulation of growth by transforming growth factor beta and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis. | 1993 | Cancer Metastasis Rev. | pmid:8281610 |