butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Hodin RA et al. | Cellular growth state differentially regulates enterocyte gene expression in butyrate-treated HT-29 cells. | 1996 | Cell Growth Differ. | pmid:8732674 |
Diener M et al. | Neuronally mediated anion secretion induced by short-chain fatty acids in the rat distal small intestine. | 1996 | Acta Physiol. Scand. | pmid:8735652 |
Cheng G et al. | [Isolation and reassociation of acetogen and methanogen in a syntrophobic coculture degrading butyrate anaerobically]. | 1995 | Wei Sheng Wu Xue Bao | pmid:8745550 |
Velázquez OC et al. | Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. | 1996 | Surgery | pmid:8751616 |
Ogryzko VV et al. | Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. | 1996 | Mol. Cell. Biol. | pmid:8756678 |
Acheson DW et al. | Translocation of Shiga toxin across polarized intestinal cells in tissue culture. | 1996 | Infect. Immun. | pmid:8757867 |
Goto I et al. | Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. | 1996 | Br. J. Cancer | pmid:8761368 |
Ghosh NK and Cox RP | Induction of human follicle-stimulating hormone in HeLa cells by sodium butyrate. | 1977 | Nature | pmid:876359 |
Dagher PC et al. | Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH. | 1996 | Am. J. Physiol. | pmid:8764164 |
Taggart MJ et al. | Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. | 1996 | Pflugers Arch. | pmid:8772130 |
Feng P et al. | Sodium butyrate is a potent modulator of smooth muscle cell proliferation and gene expression. | 1996 | Cell Prolif. | pmid:8782486 |
McBain JA et al. | Phorbol ester augments butyrate-induced apoptosis of colon cancer cells. | 1996 | Int. J. Cancer | pmid:8782664 |
Rottleb C et al. | Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression. | 1996 | Int. J. Cancer | pmid:8782665 |
Aaronson PI et al. | Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery. | 1996 | Br. J. Pharmacol. | pmid:8789392 |
Miettinen H and Huhtanen P | Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. | 1996 | J. Dairy Sci. | pmid:8792285 |
Keane MM et al. | The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. | 1996 | Cancer Res. | pmid:8797598 |
Kopf MA et al. | Key role of alkanoic acids on the spectral properties, activity, and active-site stability of iron-containing nitrile hydratase from Brevibacterium R312. | 1996 | Eur. J. Biochem. | pmid:8797859 |
Welters CF et al. | Supplementation of enteral nutrition with butyrate leads to increased portal efflux of amino acids in growing pigs with short bowel syndrome. | 1996 | J. Pediatr. Surg. | pmid:8801305 |
Chireux M et al. | Histone hyperacetylating agents stimulate promoter activity of human choline acetyltransferase gene in transfection experiment. | 1996 | Brain Res. Mol. Brain Res. | pmid:8804715 |
Wasserman LM et al. | cAMP effects on myogenic gene expression in rhabdomyosarcoma cells. | 1996 | Exp. Cell Res. | pmid:8806451 |
Lindner H et al. | Separation of acetylated core histones by hydrophilic-interaction liquid chromatography. | 1996 | J Chromatogr A | pmid:8817877 |
Kendall PE and McLeay LM | Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep. | 1996 | Res. Vet. Sci. | pmid:8819185 |
Horiuchi A and Felder RA | High-level expression of rat D1A dopamine receptor cDNA in mouse fibroblast LTK- cells by n-butyrate. | 1996 | Clin. Exp. Pharmacol. Physiol. | pmid:8819644 |
Peldszus S et al. | Determination of short-chain aliphatic, oxo- and hydroxy-acids in drinking water at low microgram per liter concentrations. | 1996 | J Chromatogr A | pmid:8819819 |
Fukamauchi F et al. | Differential effects of butyrate and dibutyryl cAMP on mRNA levels of muscarinic acetylcholine receptor subtypes expressed in neurohybrid cell lines. | 1996 | Neurosci. Lett. | pmid:8823760 |
Vaziri C et al. | Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. | 1996 | J. Biol. Chem. | pmid:8824226 |
Yamamoto I et al. | Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. | 1996 | J. Biochem. | pmid:8827437 |
Recht LD et al. | Immunotoxin sensitivity of Chinese hamster ovary cells expressing human transferrin receptors with differing internalization rates. | 1996 | Cancer Immunol. Immunother. | pmid:8830739 |
Mandal M and Kumar R | Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. | 1996 | Cell Growth Differ. | pmid:8838861 |
Whitelaw E and Williamson DH | Effects of lactation of ketogenesis from oleate or butyrate in rat hepatocytes. | 1977 | Biochem. J. | pmid:883950 |
Harig JM et al. | Transport of n-butyrate into human colonic luminal membrane vesicles. | 1996 | Am. J. Physiol. | pmid:8843764 |
Tiedge M and Lenzen S | Effects of sodium butyrate on glucose transporter and glucose-phosphorylating enzyme gene expression in RINm5F insulinoma cells. | 1996 | J. Mol. Endocrinol. | pmid:8863183 |
Velázquez OC et al. | In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-Fos and c-Jun expression. | 1996 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:8865104 |
Egawa N et al. | Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: a morphological and molecular analysis of four cell lines. | 1996 | Virchows Arch. | pmid:8865855 |
Uthayakumar S and Granger BL | Cell surface accumulation of overexpressed hamster lysosomal membrane glycoproteins. | 1995 | Cell. Mol. Biol. Res. | pmid:8867788 |
Ohbo M et al. | Effects of saturated fatty acids on amylase release from exocrine pancreatic segments of sheep, rats, hamsters, field voles and mice. | 1996 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:8870261 |
Sun R et al. | Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirus. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8876232 |
Moulding DA et al. | Modulation of neutrophil apoptosis by pharmacological agents. | 1996 | Biochem. Soc. Trans. | pmid:8879036 |
Nosbush BB et al. | Effect of concentrate source and amount in diets on plasma hormone concentrations of prepubertal heifers. | 1996 | J. Dairy Sci. | pmid:8880464 |
Roediger WE et al. | Methionine derivatives diminish sulphide damage to colonocytes--implications for ulcerative colitis. | 1996 | Gut | pmid:8881814 |
Nakai T et al. | 1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes. | 1996 | Acad Radiol | pmid:8883515 |
Rogers KM and Barnsley EA | The metabolism of S-carboxyalkylcysteines in man. | 1977 | Xenobiotica | pmid:888445 |
Sandvig K et al. | Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells. | 1996 | Mol. Biol. Cell | pmid:8885234 |
Seki J et al. | Dimethyl sulfoxide and related polar compounds enhance infection of human T cells with HIV-1 in vitro. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8886001 |
Basson MD et al. | Regulation of human colonic cell line proliferation and phenotype by sodium butyrate. | 1996 | Dig. Dis. Sci. | pmid:8888712 |
Siavoshian S et al. | Butyrate enhances major histocompatibility complex class I, HLA-DR and ICAM-1 antigen expression on differentiated human intestinal epithelial cells. | 1996 | Eur. J. Clin. Invest. | pmid:8889444 |
Thomas GL et al. | Enhanced apoptosis in transformed human lung fibroblasts after exposure to sodium butyrate. | 1996 | In Vitro Cell. Dev. Biol. Anim. | pmid:8889605 |
Treem WR et al. | Fecal short-chain fatty acids in patients with diarrhea-predominant irritable bowel syndrome: in vitro studies of carbohydrate fermentation. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8890079 |
Frazier DP et al. | The herpes simplex virus type 1 latency-associated transcript promoter is activated through Ras and Raf by nerve growth factor and sodium butyrate in PC12 cells. | 1996 | J. Virol. | pmid:8892860 |
Frazier DP et al. | Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells. | 1996 | J. Virol. | pmid:8892861 |