butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Crew TE et al. | A cyclooxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug enhances the growth inhibitory effect of butyrate in colorectal carcinoma cells expressing COX-2 protein: regulation of COX-2 by butyrate. | 2000 | Carcinogenesis | pmid:10607736 |
Watkins SM et al. | Butyric acid and tributyrin induce apoptosis in human hepatic tumour cells. | 1999 | J. Dairy Res. | pmid:10612054 |
Wu GD et al. | High-level expression of I kappa B-beta in the surface epithelium of the colon: in vitro evidence for an immunomodulatory role. | 1999 | J. Leukoc. Biol. | pmid:10614789 |
Zimmermann N et al. | Molecular analysis of CCR-3 events in eosinophilic cells. | 2000 | J. Immunol. | pmid:10623856 |
Rickard KL et al. | Short-chain fatty acids reduce expression of specific protein kinase C isoforms in human colonic epithelial cells. | 2000 | J. Cell. Physiol. | pmid:10623886 |
Pellizzaro C et al. | Cholesteryl butyrate in solid lipid nanospheres as an alternative approach for butyric acid delivery. | 1999 Sep-Oct | Anticancer Res. | pmid:10628332 |
Faber J et al. | Terminal deoxynucleotidyl transferase-negative acute lymphoblastic leukemia. | 2000 | Arch. Pathol. Lab. Med. | pmid:10629138 |
Barshishat M et al. | Butyrate regulates E-cadherin transcription, isoform expression and intracellular position in colon cancer cells. | 2000 | Br. J. Cancer | pmid:10638989 |
Hu Z et al. | Transcriptional activation of the MDR1 gene by UV irradiation. Role of NF-Y and Sp1. | 2000 | J. Biol. Chem. | pmid:10644769 |
Smith RD et al. | Quantitative PCR analysis of HbF inducers in primary human adult erythroid cells. | 2000 | Blood | pmid:10648397 |
Kleerebezem R and Stams AJ | Kinetics of syntrophic cultures: a theoretical treatise on butyrate fermentation. | 2000 | Biotechnol. Bioeng. | pmid:10649228 |
Ho LH et al. | Involvement of intracellular labile zinc in suppression of DEVD-caspase activity in human neuroblastoma cells. | 2000 | Biochem. Biophys. Res. Commun. | pmid:10652229 |
Wang XM et al. | Inhibition of proliferation, invasion and adhesion of liver cancer cells by 5-azacytidine and butyrate. | 1999 Jul-Aug | Anticancer Res. | pmid:10652571 |
Chénais B et al. | Oxidative stress involvement in chemically induced differentiation of K562 cells. | 2000 | Free Radic. Biol. Med. | pmid:10656287 |
Buommino E et al. | Sodium butyrate/retinoic acid costimulation induces apoptosis-independent growth arrest and cell differentiation in normal and ras-transformed seminal vesicle epithelial cells unresponsive to retinoic acid. | 2000 | J. Mol. Endocrinol. | pmid:10657000 |
Hodny Z et al. | Sp1 and chromatin environment are important contributors to the formation of repressive chromatin structures on the transfected human adenine nucleotide translocase-2 promoter. | 2000 | Biochem. J. | pmid:10657244 |
Garrison PM et al. | Effects of histone deacetylase inhibitors on the Ah receptor gene promoter. | 2000 | Arch. Biochem. Biophys. | pmid:10666294 |
Shin JY et al. | Mechanism for inactivation of the KIP family cyclin-dependent kinase inhibitor genes in gastric cancer cells. | 2000 | Cancer Res. | pmid:10667572 |
Wakabayashi K et al. | Bcl-2 related proteins are dramatically induced at the early stage of differentiation in human liver cancer cells by a histone deacetylase inhibitor projecting an anti-apoptotic role during this period. | 2000 Mar-Apr | Oncol. Rep. | pmid:10671672 |
Kamitani H et al. | A GATA binding site is involved in the regulation of 15-lipoxygenase-1 expression in human colorectal carcinoma cell line, caco-2. | 2000 | FEBS Lett. | pmid:10675566 |