butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
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Gargari G et al. | Consumption of a Bifidobacterium bifidum Strain for 4 Weeks Modulates Dominant Intestinal Bacterial Taxa and Fecal Butyrate in Healthy Adults. | 2016 | Appl. Environ. Microbiol. | pmid:27451450 |
Teixeira C et al. | Effects of variety and steeping conditions on some barley components associated with colonic health. | 2016 | J. Sci. Food Agric. | pmid:27450418 |
Zhou J et al. | Maternal sodium butyrate supplement elevates the lipolysis in adipose tissue and leads to lipid accumulation in offspring liver of weaning-age rats. | 2016 | Lipids Health Dis | pmid:27449927 |
Astakhova L et al. | Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells. | 2016 | PLoS ONE | pmid:27441625 |
Bai G et al. | Dietary Casein and Soy Protein Isolate Modulate the Effects of Raffinose and Fructooligosaccharides on the Composition and Fermentation of Gut Microbiota in Rats. | 2016 | J. Food Sci. | pmid:27434756 |
Sjöblom M et al. | Catalytic upgrading of butyric acid towards fine chemicals and biofuels. | 2016 | FEMS Microbiol. Lett. | pmid:26994015 |
Zhao Z et al. | Potential enhancement of direct interspecies electron transfer for syntrophic metabolism of propionate and butyrate with biochar in up-flow anaerobic sludge blanket reactors. | 2016 | Bioresour. Technol. | pmid:26967338 |
Sun J et al. | Antidepressant-like effects of sodium butyrate and its possible mechanisms of action in mice exposed to chronic unpredictable mild stress. | 2016 | Neurosci. Lett. | pmid:26957230 |
Su CL et al. | Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression. | 2016 | J Psychiatr Res | pmid:26921875 |
Valvassori SS et al. | Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain. | 2016 | Psychiatry Res | pmid:26654753 |
Mátis G et al. | Feed-drug interaction of orally applied butyrate and phenobarbital on hepatic cytochrome P450 activity in chickens. | 2016 | J Anim Physiol Anim Nutr (Berl) | pmid:26614344 |
Luceri C et al. | Effect of butyrate enemas on gene expression profiles and endoscopic/histopathological scores of diverted colorectal mucosa: A randomized trial. | 2016 | Dig Liver Dis | pmid:26607831 |
Kratsman N et al. | Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model. | 2016 | Neuropharmacology | pmid:26577018 |
Contreras-Leal E et al. | Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines. | 2016 | Mol. Carcinog. | pmid:26331238 |
Xing X et al. | Sodium butyrate protects against oxidative stress in HepG2 cells through modulating Nrf2 pathway and mitochondrial function. | 2016 | J. Physiol. Biochem. | pmid:28600747 |
Huang H et al. | Regulation of TWIK-related potassium channel-1 (Trek1) restitutes intestinal epithelial barrier function. | 2016 | Cell. Mol. Immunol. | pmid:25683610 |
Khairy H et al. | The NADH:flavin oxidoreductase Nox from Rhodococcus erythropolis MI2 is the key enzyme of 4,4'-dithiodibutyric acid degradation. | 2016 | Lett. Appl. Microbiol. | pmid:27564089 |
Kong X et al. | Inhibiting excessive acidification using zero-valent iron in anaerobic digestion of food waste at high organic load rates. | 2016 | Bioresour. Technol. | pmid:26998799 |
Bencsik R et al. | Improved transgene expression in doxycycline-inducible embryonic stem cells by repeated chemical selection or cell sorting. | 2016 | Stem Cell Res | pmid:27591479 |
Jones RJ et al. | Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. | 2015 | Bioresour. Technol. | pmid:25898090 |
Deng Y et al. | Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. | 2015 | J. Biotechnol. | pmid:26535965 |
Durlak M et al. | A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. | 2015 | PLoS ONE | pmid:26509275 |
Sasajima H et al. | Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. | 2015 | Neurotoxicology | pmid:26493152 |
Huang C et al. | Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. | 2015 | J. Nutr. | pmid:26491121 |
Patman G | Gut microbiota: Lactobacillus acidophilus opens the door to butyrate. | 2015 | Nat Rev Gastroenterol Hepatol | pmid:26323876 |
Desai VH et al. | Receptor-Guided De Novo Design of Dengue Envelope Protein Inhibitors. | 2015 | Appl. Biochem. Biotechnol. | pmid:26299376 |
Kumar A et al. | Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26272259 |
Kumar P et al. | Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. | 2015 | PLoS ONE | pmid:26266541 |
Li L et al. | Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. | 2015 | J. Food Sci. | pmid:26256258 |
Shang HM et al. | Effects of dietary polysaccharides from the submerged fermentation concentrate of Hericium caput-medusae (Bull.:Fr.) Pers. on fat deposition in broilers. | 2015 | J. Sci. Food Agric. | pmid:24771556 |
Bucki R et al. | Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. | 2015 | Antimicrob. Agents Chemother. | pmid:26248361 |
Chen Y et al. | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. | 2015 | Cardiovasc Diabetol | pmid:26245924 |
Chaturvedi K et al. | Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. | 2015 | Nanomedicine (Lond) | pmid:26008194 |
Theparambil SM et al. | Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes. | 2015 | J. Physiol. (Lond.) | pmid:25990710 |
Chou YC et al. | Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells. | 2015 | Mol. Cell. Biol. | pmid:25986606 |
Gurav A et al. | Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. | 2015 | Biochem. J. | pmid:25984582 |
Chen JH and Chou CC | Acrylamide inhibits cellular differentiation of human neuroblastoma and glioblastoma cells. | 2015 | Food Chem. Toxicol. | pmid:25959841 |
Conlon MA et al. | Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. | 2015 | J. Nutr. | pmid:25934666 |
Steckert AV et al. | Effects of sodium butyrate on aversive memory in rats submitted to sepsis. | 2015 | Neurosci. Lett. | pmid:25888815 |
Castino MR et al. | Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. | 2015 | PLoS ONE | pmid:25880762 |
Li L et al. | Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells. | 2015 | BMC Biochem. | pmid:25592494 |
Henagan TM et al. | Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. | 2015 | Br. J. Pharmacol. | pmid:25559882 |
Weaver EM et al. | Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. | 2015 | Eur. J. Pharmacol. | pmid:25557765 |
Arai T et al. | Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. | 2015 | J. Microbiol. Methods | pmid:25555820 |
Shimizu T et al. | Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. | 2015 | J Physiol Sci | pmid:25544596 |
Huang C et al. | Evaluating the possibility of using acetone-butanol-ethanol (ABE) fermentation wastewater for bacterial cellulose production by Gluconacetobacter xylinus. | 2015 | Lett. Appl. Microbiol. | pmid:25615895 |
Mátis G et al. | Effects of oral butyrate application on insulin signaling in various tissues of chickens. | 2015 | Domest. Anim. Endocrinol. | pmid:25240231 |
Esteras N et al. | G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. | 2015 | Mol. Neurobiol. | pmid:25182869 |
Cottier F et al. | MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. | 2015 | Eukaryotic Cell | pmid:26297702 |
Chen F et al. | Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. | 2015 | Carbohydr Polym | pmid:26256366 |