butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
Loading... please refresh the page if content is not showing up.

Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
Loading... please refresh the page if content is not showing up.

What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

Download all related citations
Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Etschmann B et al. A vH+-ATPase is present in cultured sheep ruminal epithelial cells. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16825706
Kiela PR et al. Regulation of the rat NHE3 gene promoter by sodium butyrate. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11557515
Jørgensen J and Mortensen PB Substrate utilization by intestinal mucosal tissue strips from patients with inflammatory bowel disease. 2001 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11447021
Aschenbach JR et al. Bicarbonate-dependent and bicarbonate-independent mechanisms contribute to nondiffusive uptake of acetate in the ruminal epithelium of sheep. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:19264953
Shie JL et al. Role of gut-enriched Krüppel-like factor in colonic cell growth and differentiation. 2000 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:11005769
Suply E et al. Butyrate enemas enhance both cholinergic and nitrergic phenotype of myenteric neurons and neuromuscular transmission in newborn rat colon. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22492692
Ramasamy S et al. Sulfide-detoxifying enzymes in the human colon are decreased in cancer and upregulated in differentiation. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16500920
Subramanya SB et al. Differential regulation of cholera toxin-inhibited Na-H exchange isoforms by butyrate in rat ileum. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17690171
Fukushima K and Fiocchi C Paradoxical decrease of mitochondrial DNA deletions in epithelial cells of active ulcerative colitis patients. 2004 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:15068964
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Amin MR et al. Involvement of Sp1 and Sp3 in differential regulation of human NHE3 promoter activity by sodium butyrate and IFN-gamma/TNF-alpha. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17540780
Xu H et al. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26159698
Parhar K et al. Short-chain fatty acid mediated phosphorylation of heat shock protein 25: effects on camptothecin-induced apoptosis. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16469826
Archer SY et al. The histone deacetylase inhibitor butyrate downregulates cyclin B1 gene expression via a p21/WAF-1-dependent mechanism in human colon cancer cells. 2005 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16160080
Borthakur A et al. Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16150873
Srinivas SR et al. Transport of butyryl-L-carnitine, a potential prodrug, via the carnitine transporter OCTN2 and the amino acid transporter ATB(0,+). 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17855766
Kolar SS et al. Synergy between docosahexaenoic acid and butyrate elicits p53-independent apoptosis via mitochondrial Ca(2+) accumulation in colonocytes. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:17717041
Cao Y et al. Dietary fiber enhances TGF-β signaling and growth inhibition in the gut. 2011 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:21454444
Saksena S et al. Mechanisms underlying modulation of monocarboxylate transporter 1 (MCT1) by somatostatin in human intestinal epithelial cells. 2009 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:20501436
Venkatraman A et al. Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637250
Grider JR and Piland BE The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16973914
Sonoyama K et al. Upregulation of activin A gene by butyrate in human colon cancer cell lines. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12540370
Vinolo MA et al. Tributyrin attenuates obesity-associated inflammation and insulin resistance in high-fat-fed mice. 2012 Am. J. Physiol. Endocrinol. Metab. pmid:22621868
Silva P et al. Competition between sodium reabsorption and gluconeogenesis in kidneys of steroid-treated rats. 1980 Am. J. Physiol. pmid:7377301
Chacin J et al. Role of oxalacetate in lipoate effect on frog gastric mucosa. 1976 Am. J. Physiol. pmid:8990
Nutting CW et al. Vasorelaxant effects of short chain fatty acid salts in rat caudal artery. 1991 Am. J. Physiol. pmid:1877681
Jentsch TJ et al. Electrical properties of sodium bicarbonate symport in kidney epithelial cells (BSC-1). 1986 Am. J. Physiol. pmid:3024506
Cairns SP and Dulhunty AF Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat. 1994 Am. J. Physiol. pmid:8203484
Brazy PC et al. Interactions between phosphate and oxidative metabolism in proximal renal tubules. 1984 Am. J. Physiol. pmid:6496685
Gullans SR et al. Stimulation of phosphate transport in the proximal tubule by metabolic substrates. 1984 Am. J. Physiol. pmid:6496686
Bourne GA and Baldwin DM Evidence for cAMP as a mediator of gonadotropin secretion from female pituitaries. 1987 Am. J. Physiol. pmid:2820237
Stanton RC et al. Use of monoclonal antibodies to culture rat proximal tubule cells. 1986 Am. J. Physiol. pmid:3022594
Cheng SH et al. Functional activation of the cystic fibrosis trafficking mutant delta F508-CFTR by overexpression. 1995 Am. J. Physiol. pmid:7733303
Ardaillou N et al. Vasoconstrictor-evoked prostaglandin synthesis in cultured human mesangial cells. 1985 Am. J. Physiol. pmid:3918460
Brubaker PL et al. Synthesis and secretion of somatostatin-28 and -14 by fetal rat intestinal cells in culture. 1990 Am. J. Physiol. pmid:1694403
Tarloff JB and Brand PH Active tetraethylammonium uptake across the basolateral membrane of rabbit proximal tubule. 1986 Am. J. Physiol. pmid:3728682
Albina JE and Mastrofrancesco B Modulation of glucose metabolism in macrophages by products of nitric oxide synthase. 1993 Am. J. Physiol. pmid:7687412
Dobson A et al. Absorption and exchange of water across rumen epithelium. 1976 Am. J. Physiol. pmid:998805
O'Donnell ME and Horwitz BA Effects of butyrate on ouabain-sensitive respiration of hamster brown adipocytes. 1982 Am. J. Physiol. pmid:7058878
Mailman D et al. Villous motility and unstirred water layers in canine intestine. 1990 Am. J. Physiol. pmid:2305890
Sussman NL et al. Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes. 1989 Am. J. Physiol. pmid:2546440
Hollander D and Rim E Effect of luminal constituents on vitamin K1 absorption into thoracic duct lymph. 1978 Am. J. Physiol. pmid:623249
Mariadason JM et al. Effect of short-chain fatty acids on paracellular permeability in Caco-2 intestinal epithelium model. 1997 Am. J. Physiol. pmid:9142899
Subero O et al. Ca2+ requirement for metabolic effects of secretagogues in the amphibian gastric mucosa. 1989 Am. J. Physiol. pmid:2514602
Chander A Regulation of lung surfactant secretion by intracellular pH. 1989 Am. J. Physiol. pmid:2514603
Keller SK et al. Interactions of pH and K+ conductance in cultured bovine retinal pigment epithelial cells. 1986 Am. J. Physiol. pmid:3942203
Nishimura A et al. Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells. 1998 Am. J. Physiol. pmid:9688874
Holtbäck U et al. Neuropeptide Y shifts equilibrium between alpha- and beta-adrenergic tonus in proximal tubule cells. 1998 Am. J. Physiol. pmid:9688998
Rome L et al. Proximal tubule volume regulation in hyperosmotic media: intracellular K+, Na+, and Cl-. 1989 Am. J. Physiol. pmid:2610250
Hollander D et al. Transport of butyric acid in vascularly perfused anuran small intestine: importance of pH and anion transport. 1986 Am. J. Physiol. pmid:3485924