butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with butyric acid
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Foote AP and Freetly HC | Effect of abomasal butyrate infusion on net nutrient flux across the portal-drained viscera and liver of growing lambs. | 2016 | J. Anim. Sci. | pmid:27482683 |
Terova G et al. | Effects of Sodium Butyrate Treatment on Histone Modifications and the Expression of Genes Related to Epigenetic Regulatory Mechanisms and Immune Response in European Sea Bass (Dicentrarchus Labrax) Fed a Plant-Based Diet. | 2016 | PLoS ONE | pmid:27471849 |
Jawed K et al. | Engineered Production of Short Chain Fatty Acid in Escherichia coli Using Fatty Acid Synthesis Pathway. | 2016 | PLoS ONE | pmid:27466817 |
Early JV et al. | Oxadiazoles Have Butyrate-Specific Conditional Activity against Mycobacterium tuberculosis. | 2016 | Antimicrob. Agents Chemother. | pmid:27044545 |
He B et al. | Effects of sodium butyrate supplementation on reproductive performance and colostrum composition in gilts. | 2016 | Animal | pmid:27040131 |
Petry FS et al. | Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction. | 2016 | Behav. Brain Res. | pmid:27025446 |
Frycz BA et al. | Transcript level of AKR1C3 is down-regulated in gastric cancer. | 2016 | Biochem. Cell Biol. | pmid:27019068 |
Li H et al. | Sodium butyrate exerts neuroprotective effects by restoring the blood-brain barrier in traumatic brain injury mice. | 2016 | Brain Res. | pmid:27017959 |
Ng CH and Yang KL | Lipase in biphasic alginate beads as a biocatalyst for esterification of butyric acid and butanol in aqueous media. | 2016 | Enzyme Microb. Technol. | pmid:26672465 |
Han A et al. | Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. | 2016 | J. Cell. Physiol. | pmid:26661480 |
Tiwari P et al. | Preventive effects of butyric acid, nicotinamide, calcium glucarate alone or in combination during the 7, 12-dimethylbenz (a) anthracene induced mouse skin tumorigenesis via modulation of K-Ras-PI3K-AKTpathway and associated micro RNAs. | 2016 | Biochimie | pmid:26655363 |
Junicke H et al. | Kinetic and thermodynamic control of butyrate conversion in non-defined methanogenic communities. | 2016 | Appl. Microbiol. Biotechnol. | pmid:26403924 |
Ayers LW et al. | Changes in dam and pup behavior following repeated postnatal exposure to a predator odor (TMT): A preliminary investigation in Long-Evans rats. | 2016 | Dev Psychobiol | pmid:26394891 |
Reddy YS et al. | Study on Synthesis, Characterization and Antiproliferative Activity of Novel Diisopropylphenyl Esters of Selected Fatty Acids. | 2016 | J Oleo Sci | pmid:26666272 |
Polycarpo GV et al. | Effects of lipid sources, lysophospholipids and organic acids in maize-based broiler diets on nutrient balance, liver concentration of fat-soluble vitamins, jejunal microbiota and performance. | 2016 | Br. Poult. Sci. | pmid:27494540 |
Kim M et al. | Butyric acid production from softwood hydrolysate by acetate-consuming Clostridium sp. S1 with high butyric acid yield and selectivity. | 2016 | Bioresour. Technol. | pmid:27474955 |
Tochio T et al. | An Alteration in the Cecal Microbiota Composition by Feeding of 1-Kestose Results in a Marked Increase in the Cecal Butyrate Content in Rats. | 2016 | PLoS ONE | pmid:27861621 |
Tian H et al. | Discovery of a Flexible Triazolylbutanoic Acid as a Highly Potent Uric Acid Transporter 1 (URAT1) Inhibitor. | 2016 | Molecules | pmid:27854343 |
Neis EP et al. | Effects of Liver Resection on Hepatic Short-Chain Fatty Acid Metabolism in Humans. | 2016 | PLoS ONE | pmid:27835668 |
Yan H and Ajuwon KM | Mechanism of Butyrate Stimulation of Triglyceride Storage and Adipokine Expression during Adipogenic Differentiation of Porcine Stromovascular Cells. | 2015 | PLoS ONE | pmid:26713737 |
Jones RJ et al. | Removal and recovery of inhibitory volatile fatty acids from mixed acid fermentations by conventional electrodialysis. | 2015 | Bioresour. Technol. | pmid:25898090 |
Tian H et al. | Anaerobic co-digestion of kitchen waste and pig manure with different mixing ratios. | 2015 | J. Biosci. Bioeng. | pmid:25617184 |
Zheng XT et al. | Sodium butyrate down-regulates tristetraprolin-mediated cyclin B1 expression independent of the formation of processing bodies. | 2015 | Int. J. Biochem. Cell Biol. | pmid:26555753 |
Deng Y et al. | Driving carbon flux through exogenous butyryl-CoA: Acetate CoA-transferase to produce butyric acid at high titer in Thermobifida fusca. | 2015 | J. Biotechnol. | pmid:26535965 |
Durlak M et al. | A Novel High-Content Immunofluorescence Assay as a Tool to Identify at the Single Cell Level γ-Globin Inducing Compounds. | 2015 | PLoS ONE | pmid:26509275 |
Sasajima H et al. | Intranasal administration of rotenone in mice attenuated olfactory functions through the lesion of dopaminergic neurons in the olfactory bulb. | 2015 | Neurotoxicology | pmid:26493152 |
Huang C et al. | Dietary Sodium Butyrate Decreases Postweaning Diarrhea by Modulating Intestinal Permeability and Changing the Bacterial Communities in Weaned Piglets. | 2015 | J. Nutr. | pmid:26491121 |
Luo H et al. | Enhancing Butanol Production under the Stress Environments of Co-Culturing Clostridium acetobutylicum/Saccharomyces cerevisiae Integrated with Exogenous Butyrate Addition. | 2015 | PLoS ONE | pmid:26489085 |
Alva-Murillo N et al. | The activation of the TLR2/p38 pathway by sodium butyrate in bovine mammary epithelial cells is involved in the reduction of Staphylococcus aureus internalization. | 2015 | Mol. Immunol. | pmid:26471700 |
Turon V et al. | Growth of Chlorella sorokiniana on a mixture of volatile fatty acids: The effects of light and temperature. | 2015 | Bioresour. Technol. | pmid:26461792 |
Muñoz-Rugeles L and Alvarez-Idaboy JR | A proton-electron sequential transfer mechanism: theoretical evidence about its biological relevance. | 2015 | Phys Chem Chem Phys | pmid:26456543 |
Sari O et al. | Synthesis of dihydropyrimidine α,γ-diketobutanoic acid derivatives targeting HIV integrase. | 2015 | Eur J Med Chem | pmid:26451771 |
Jin CJ et al. | Supplementation of sodium butyrate protects mice from the development of non-alcoholic steatohepatitis (NASH). | 2015 | Br. J. Nutr. | pmid:26450277 |
Rajendran VM et al. | Na-H Exchanger Isoform-2 (NHE2) Mediates Butyrate-dependent Na+ Absorption in Dextran Sulfate Sodium (DSS)-induced Colitis. | 2015 | J. Biol. Chem. | pmid:26350456 |
Rawłuszko-Wieczorek AA et al. | Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer. | 2015 | Biomed. Pharmacother. | pmid:26349991 |
Sobolewski C et al. | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. | 2015 | Biomolecules | pmid:26343742 |
Fomina-Yadlin D et al. | Transcriptome analysis of a CHO cell line expressing a recombinant therapeutic protein treated with inducers of protein expression. | 2015 | J. Biotechnol. | pmid:26325199 |
Patman G | Gut microbiota: Lactobacillus acidophilus opens the door to butyrate. | 2015 | Nat Rev Gastroenterol Hepatol | pmid:26323876 |
Desai VH et al. | Receptor-Guided De Novo Design of Dengue Envelope Protein Inhibitors. | 2015 | Appl. Biochem. Biotechnol. | pmid:26299376 |
Kumar A et al. | Lactobacillus acidophilus counteracts enteropathogenic E. coli-induced inhibition of butyrate uptake in intestinal epithelial cells. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:26272259 |
Kumar P et al. | Differential Effects of Sodium Butyrate and Lithium Chloride on Rhesus Monkey Trophoblast Differentiation. | 2015 | PLoS ONE | pmid:26266541 |
Li L et al. | Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces. | 2015 | J. Food Sci. | pmid:26256258 |
Shang HM et al. | Effects of dietary polysaccharides from the submerged fermentation concentrate of Hericium caput-medusae (Bull.:Fr.) Pers. on fat deposition in broilers. | 2015 | J. Sci. Food Agric. | pmid:24771556 |
Bucki R et al. | Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection. | 2015 | Antimicrob. Agents Chemother. | pmid:26248361 |
Chen Y et al. | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. | 2015 | Cardiovasc Diabetol | pmid:26245924 |
Wang X et al. | Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway. | 2015 | Sci Rep | pmid:26234821 |
Regestein L et al. | Impact of butyric acid on butanol formation by Clostridium pasteurianum. | 2015 | Bioresour. Technol. | pmid:26233327 |
Baroi GN et al. | Butyric acid fermentation from pretreated and hydrolysed wheat straw by an adapted Clostridium tyrobutyricum strain. | 2015 | Microb Biotechnol | pmid:26230610 |
Zhong Y et al. | Barley malt increases hindgut and portal butyric acid, modulates gene expression of gut tight junction proteins and Toll-like receptors in rats fed high-fat diets, but high advanced glycation end-products partially attenuate the effects. | 2015 | Food Funct | pmid:26227569 |
Sandoval PY et al. | Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena. | 2015 | PLoS Genet. | pmid:26218270 |
Valvassori SS et al. | Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress. | 2015 | Curr Neurovasc Res | pmid:26216027 |
Qaisrani SN et al. | Diet structure, butyric acid, and fermentable carbohydrates influence growth performance, gut morphology, and cecal fermentation characteristics in broilers. | 2015 | Poult. Sci. | pmid:26175052 |
Lee KM et al. | Butyric acid production from red algae by a newly isolated Clostridium sp. S1. | 2015 | Biotechnol. Lett. | pmid:26026964 |
Jiang L et al. | Thermophilic hydrogen-producing bacteria inhabiting deep-sea hydrothermal environments represented by Caloranaerobacter. | 2015 | Res. Microbiol. | pmid:26026841 |
Agarwal U et al. | Role of rumen butyrate in regulation of nitrogen utilization and urea nitrogen kinetics in growing sheep. | 2015 | J. Anim. Sci. | pmid:26020334 |
Gao F et al. | The Effect of Processing Additives on Energetic Disorder in Highly Efficient Organic Photovoltaics: A Case Study on PBDTTT-C-T:PC71 BM. | 2015 | Adv. Mater. Weinheim | pmid:26016473 |
Levy AW et al. | Effect of feeding an encapsulated source of butyric acid (ButiPEARL) on the performance of male Cobb broilers reared to 42 d of age. | 2015 | Poult. Sci. | pmid:26015588 |
Liu H et al. | Post-occlusion administration of sodium butyrate attenuates cognitive impairment in a rat model of chronic cerebral hypoperfusion. | 2015 | Pharmacol. Biochem. Behav. | pmid:26013850 |
Chaturvedi K et al. | Oral insulin delivery using deoxycholic acid conjugated PEGylated polyhydroxybutyrate co-polymeric nanoparticles. | 2015 | Nanomedicine (Lond) | pmid:26008194 |
Theparambil SM et al. | Reversed electrogenic sodium bicarbonate cotransporter 1 is the major acid loader during recovery from cytosolic alkalosis in mouse cortical astrocytes. | 2015 | J. Physiol. (Lond.) | pmid:25990710 |
Chou YC et al. | Pharmacological Induction of Human Fetal Globin Gene in Hydroxyurea-Resistant Primary Adult Erythroid Cells. | 2015 | Mol. Cell. Biol. | pmid:25986606 |
Gurav A et al. | Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions. | 2015 | Biochem. J. | pmid:25984582 |
Chen JH and Chou CC | Acrylamide inhibits cellular differentiation of human neuroblastoma and glioblastoma cells. | 2015 | Food Chem. Toxicol. | pmid:25959841 |
Conlon MA et al. | Lowering of large bowel butyrate levels in healthy populations is unlikely to be beneficial. | 2015 | J. Nutr. | pmid:25934666 |
Steckert AV et al. | Effects of sodium butyrate on aversive memory in rats submitted to sepsis. | 2015 | Neurosci. Lett. | pmid:25888815 |
Castino MR et al. | Inhibition of histone deacetylases facilitates extinction and attenuates reinstatement of nicotine self-administration in rats. | 2015 | PLoS ONE | pmid:25880762 |
Ulfina GG et al. | Modulation of post-partum reproductive performance in dairy cows through supplementation of long- or short-chain fatty acids during transition period. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:25879374 |
Blank M et al. | Enhancement of memory consolidation by the histone deacetylase inhibitor sodium butyrate in aged rats. | 2015 | Neurosci. Lett. | pmid:25837444 |
Gonnella R et al. | PKC theta and p38 MAPK activate the EBV lytic cycle through autophagy induction. | 2015 | Biochim. Biophys. Acta | pmid:25827954 |
Shimoyama T et al. | Study of the mechanisms of a Japanese traditional fermented medicine in the improvement of constipation. | 2015 | J. Gastroenterol. Hepatol. | pmid:25827805 |
Huang YW et al. | Brain isoform glycogen phosphorylase as a novel hepatic progenitor cell marker. | 2015 | PLoS ONE | pmid:25826279 |
Chen L et al. | Free and bound volatile chemicals in mulberry (Morus atropurpurea Roxb.). | 2015 | J. Food Sci. | pmid:25817411 |
Cueno ME et al. | High butyric acid amounts induce oxidative stress, alter calcium homeostasis, and cause neurite retraction in nerve growth factor-treated PC12 cells. | 2015 | Cell Stress Chaperones | pmid:25808460 |
Kanika G et al. | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. | 2015 | J. Biochem. Mol. Toxicol. | pmid:25774002 |
Zhang T et al. | Sodium Butyrate Reduces Organ Injuries in Mice with Severe Acute Pancreatitis Through Inhibiting HMGB1 Expression. | 2015 | Dig. Dis. Sci. | pmid:25686746 |
Wanat P et al. | Short communication: Effect of inclusion rate of microencapsulated sodium butyrate in starter mixture for dairy calves. | 2015 | J. Dairy Sci. | pmid:25648817 |
Gerace E et al. | Interplay between histone acetylation/deacetylation and poly(ADP-ribosyl)ation in the development of ischemic tolerance in vitro. | 2015 | Neuropharmacology | pmid:25623965 |
Li L et al. | Histone deacetylase inhibitor sodium butyrate suppresses DNA double strand break repair induced by etoposide more effectively in MCF-7 cells than in HEK293 cells. | 2015 | BMC Biochem. | pmid:25592494 |
Henagan TM et al. | Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning. | 2015 | Br. J. Pharmacol. | pmid:25559882 |
Weaver EM et al. | Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells. | 2015 | Eur. J. Pharmacol. | pmid:25557765 |
Arai T et al. | Actinomyces naeslundii GroEL-dependent initial attachment and biofilm formation in a flow cell system. | 2015 | J. Microbiol. Methods | pmid:25555820 |
Shimizu T et al. | Volume-sensitive outwardly rectifying Cl(-) channels contribute to butyrate-triggered apoptosis of murine colonic epithelial MCE301 cells. | 2015 | J Physiol Sci | pmid:25544596 |
Rodrigues MF et al. | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. | 2015 | J. Cell. Biochem. | pmid:25510910 |
Huang C et al. | Evaluating the possibility of using acetone-butanol-ethanol (ABE) fermentation wastewater for bacterial cellulose production by Gluconacetobacter xylinus. | 2015 | Lett. Appl. Microbiol. | pmid:25615895 |
Ledaki I et al. | Carbonic anhydrase IX induction defines a heterogeneous cancer cell response to hypoxia and mediates stem cell-like properties and sensitivity to HDAC inhibition. | 2015 | Oncotarget | pmid:26305601 |
Tiwari P et al. | Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events. | 2015 | Chem. Biol. Interact. | pmid:25478867 |
Varela RB et al. | Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats. | 2015 | J Psychiatr Res | pmid:25467060 |
Turon V et al. | Use of fermentative metabolites for heterotrophic microalgae growth: Yields and kinetics. | 2015 | Bioresour. Technol. | pmid:25459841 |
Barichello T et al. | Sodium Butyrate Prevents Memory Impairment by Re-establishing BDNF and GDNF Expression in Experimental Pneumococcal Meningitis. | 2015 | Mol. Neurobiol. | pmid:25284351 |
Mátis G et al. | Effects of oral butyrate application on insulin signaling in various tissues of chickens. | 2015 | Domest. Anim. Endocrinol. | pmid:25240231 |
Esteras N et al. | G1/S Cell Cycle Checkpoint Dysfunction in Lymphoblasts from Sporadic Parkinson's Disease Patients. | 2015 | Mol. Neurobiol. | pmid:25182869 |
Ray A et al. | Absorption spectrophotometric, fluorescence and quantum chemical investigations on non-covalent interaction between PC₇₀BM and designed diporphyrin in solution. | 2015 | Spectrochim Acta A Mol Biomol Spectrosc | pmid:25138385 |
Szymanowska-Powałowska D and Kubiak P | Effect of 1,3-propanediol, organic acids, and ethanol on growth and metabolism of Clostridium butyricum DSP1. | 2015 | Appl. Microbiol. Biotechnol. | pmid:25524700 |
Cottier F et al. | MIG1 Regulates Resistance of Candida albicans against the Fungistatic Effect of Weak Organic Acids. | 2015 | Eukaryotic Cell | pmid:26297702 |
Dengler F et al. | Both butyrate incubation and hypoxia upregulate genes involved in the ruminal transport of SCFA and their metabolites. | 2015 | J Anim Physiol Anim Nutr (Berl) | pmid:24804847 |
Chen F et al. | Unusual effects of monocarboxylic acids on the structure and on the transport and mechanical properties of chitosan films. | 2015 | Carbohydr Polym | pmid:26256366 |
Katsou E et al. | Coupling the treatment of low strength anaerobic effluent with fermented biowaste for nutrient removal via nitrite. | 2015 | J. Environ. Manage. | pmid:25463576 |
Park SO and Park BS | Bifidogenic effect of grain larvae extract on serum lipid, glucose and intestinal microflora in rats. | 2015 | J. Biosci. | pmid:26333397 |
Pawelka AJ and Huizinga JD | Induction of rhythmic transient depolarizations associated with waxing and waning of slow wave activity in intestinal smooth muscle. | 2015 | Am. J. Physiol. Gastrointest. Liver Physiol. | pmid:25540235 |
Xiong XR et al. | Sodium butyrate improves the cloned yak embryo viability and corrects gene expression patterns. | 2015 | Zygote | pmid:23759515 |