butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

Cross Reference

Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Ovarian Neoplasms D010051 10 associated lipids
Diabetic Ketoacidosis D016883 16 associated lipids
Lupus Erythematosus, Systemic D008180 43 associated lipids
Lung Neoplasms D008175 171 associated lipids
Burns D002056 34 associated lipids
Insulinoma D007340 28 associated lipids
Pancreatic Neoplasms D010190 77 associated lipids
Colitis D003092 69 associated lipids
Colonic Neoplasms D003110 161 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetic Retinopathy D003930 39 associated lipids
Cattle Diseases D002418 24 associated lipids
Fatty Liver D005234 48 associated lipids
Ketosis D007662 13 associated lipids
Sarcoma 180 D012510 21 associated lipids
Body Weight D001835 333 associated lipids
Edema D004487 152 associated lipids
Corneal Diseases D003316 13 associated lipids
Prostatic Neoplasms D011471 126 associated lipids
Osteosarcoma D012516 50 associated lipids
Carcinoma, Small Cell D018288 21 associated lipids
Hypothyroidism D007037 32 associated lipids
Leukemia, Erythroblastic, Acute D004915 41 associated lipids
Melanoma D008545 69 associated lipids
Occupational Diseases D009784 42 associated lipids
Weight Gain D015430 101 associated lipids
Brain Diseases D001927 27 associated lipids
Acidosis D000138 13 associated lipids
Glioma D005910 112 associated lipids
Cell Transformation, Neoplastic D002471 126 associated lipids
Liver Neoplasms, Experimental D008114 46 associated lipids
Thrombosis D013927 49 associated lipids
Peritonitis D010538 38 associated lipids
Lymphoma D008223 18 associated lipids
Alzheimer Disease D000544 76 associated lipids
Dentin, Secondary D003809 2 associated lipids
Thyroid Neoplasms D013964 33 associated lipids
Leukemia D007938 74 associated lipids
Neuroblastoma D009447 66 associated lipids
Carcinoma, Hepatocellular D006528 140 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Per page 10 20 50 100 | Total 7933
Authors Title Published Journal PubMed Link
Suply E et al. Butyrate enemas enhance both cholinergic and nitrergic phenotype of myenteric neurons and neuromuscular transmission in newborn rat colon. 2012 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:22492692
Cremin JD et al. Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637251
Xu H et al. Sodium butyrate stimulates NHE8 expression via its role on activating NHE8 basal promoter activity. 2015 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:26159698
Borthakur A et al. Enteropathogenic Escherichia coli inhibits butyrate uptake in Caco-2 cells by altering the apical membrane MCT1 level. 2006 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16150873
Venkatraman A et al. Amelioration of dextran sulfate colitis by butyrate: role of heat shock protein 70 and NF-kappaB. 2003 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12637250
Grider JR and Piland BE The peristaltic reflex induced by short-chain fatty acids is mediated by sequential release of 5-HT and neuronal CGRP but not BDNF. 2007 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:16973914
Bao JX et al. Triggering role of acid sphingomyelinase in endothelial lysosome-membrane fusion and dysfunction in coronary arteries. 2010 Am. J. Physiol. Heart Circ. Physiol. pmid:20061541
Ochiai K et al. Effects of augmented delivery of pyruvate on myocardial high-energy phosphate metabolism at high workstate. 2001 Am. J. Physiol. Heart Circ. Physiol. pmid:11557577
Rexhaj E et al. Fetal programming of pulmonary vascular dysfunction in mice: role of epigenetic mechanisms. 2011 Am. J. Physiol. Heart Circ. Physiol. pmid:21536851
Park GY et al. Regulation of macrophage cyclooxygenase-2 gene expression by modifications of histone H3. 2004 Am. J. Physiol. Lung Cell Mol. Physiol. pmid:14672923
Zhao L et al. ¹H-NMR-based metabonomic analysis of metabolic profiling in diabetic nephropathy rats induced by streptozotocin. 2011 Am. J. Physiol. Renal Physiol. pmid:21228107
Nakhoul NL et al. Ammonium interaction with the epithelial sodium channel. 2001 Am. J. Physiol. Renal Physiol. pmid:11502598
Laughery MD et al. Selective basolateral localization of overexpressed Na-K-ATPase beta1- and beta2- subunits is disrupted by butryate treatment of MDCK cells. 2007 Am. J. Physiol. Renal Physiol. pmid:17344187
Kumar P et al. Inhibition of HDAC enhances STAT acetylation, blocks NF-κB, and suppresses the renal inflammation and fibrosis in haplotype male mice. 2017 Am. J. Physiol. Renal Physiol. pmid:28566502
Brown AC et al. RhCG is the major putative ammonia transporter expressed in the human kidney, and RhBG is not expressed at detectable levels. 2009 Am. J. Physiol. Renal Physiol. pmid:19357182
Leipziger J et al. PKA site mutations of ROMK2 channels shift the pH dependence to more alkaline values. 2000 Am. J. Physiol. Renal Physiol. pmid:11053053
Gill RK and Dudeja PK A novel facet to consider for the effects of butyrate on its target cells. Focus on "The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein". 2011 Am. J. Physiol., Cell Physiol. pmid:21832244
Gonçalves P et al. The short-chain fatty acid butyrate is a substrate of breast cancer resistance protein. 2011 Am. J. Physiol., Cell Physiol. pmid:21775706
Lam P et al. Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases. 2007 Am. J. Physiol., Cell Physiol. pmid:17855769
Loffing-Cueni D et al. Trafficking of GFP-tagged DeltaF508-CFTR to the plasma membrane in a polarized epithelial cell line. 2001 Am. J. Physiol., Cell Physiol. pmid:11698247
Nakhoul NL et al. pH sensitivity of ammonium transport by Rhbg. 2010 Am. J. Physiol., Cell Physiol. pmid:20810915
Cooper GJ and Fong P Relationship between intracellular pH and chloride in Xenopus oocytes expressing the chloride channel ClC-0. 2003 Am. J. Physiol., Cell Physiol. pmid:12388074
Said HM et al. Mechanism of nicotinic acid transport in human liver cells: experiments with HepG2 cells and primary hepatocytes. 2007 Am. J. Physiol., Cell Physiol. pmid:17928533
Kiela PR et al. Molecular mechanism of rat NHE3 gene promoter regulation by sodium butyrate. 2007 Am. J. Physiol., Cell Physiol. pmid:17344314
Krishnan S et al. Apical NHE isoforms differentially regulate butyrate-stimulated Na absorption in rat distal colon. 2003 Am. J. Physiol., Cell Physiol. pmid:12878493
Resta-Lenert S et al. Inhibition of epithelial chloride secretion by butyrate: role of reduced adenylyl cyclase expression and activity. 2001 Am. J. Physiol., Cell Physiol. pmid:11698242
Cao XX et al. Histone deacetylase inhibitor downregulation of bcl-xl gene expression leads to apoptotic cell death in mesothelioma. 2001 Am. J. Respir. Cell Mol. Biol. pmid:11713097
Andrews FM et al. In vitro effects of hydrochloric acid and various concentrations of acetic, propionic, butyric, or valeric acids on bioelectric properties of equine gastric squamous mucosa. 2006 Am. J. Vet. Res. pmid:17078749
Minder HP et al. In vitro fermentation of feces from normal and chronically diarrheal horses. 1980 Am. J. Vet. Res. pmid:6447466
Allemann M et al. Effect of sodium butyric acid, sodium valerianic acid, and osmolarity on contractility of specimens of intestinal wall obtained from the cecum and spiral colon of healthy cows. 2000 Am. J. Vet. Res. pmid:10850845
Targowski SP and Klucinski W Reduction in mitogenic response of bovine lymphocytes by ketone bodies. 1983 Am. J. Vet. Res. pmid:6603180
Mills SW et al. Evaluation of the effects of short-chain fatty acids and extracellular pH on bovine neutrophil function in vitro. 2006 Am. J. Vet. Res. pmid:17078753
Theodorou EC et al. Activation of the AtoSC two-component system in the absence of the AtoC N-terminal receiver domain in E. coli. 2011 Amino Acids pmid:20563612
Pinto JT et al. Chemopreventive mechanisms of α-keto acid metabolites of naturally occurring organoselenium compounds. 2011 Amino Acids pmid:20383543
Abecia L et al. Biodiversity and fermentative activity of caecal microbial communities in wild and farm rabbits from Spain. 2012 Anaerobe pmid:22561060
Dunkley KD et al. Growth and genetic responses of Salmonella Typhimurium to pH-shifts in an anaerobic continuous culture. 2008 Anaerobe pmid:18061487
Narayanan N et al. Isolation and culturing of a most common anaerobic ciliate, Metopus sp. 2007 Anaerobe pmid:17223583
Zampa A et al. Effects of different digestible carbohydrates on bile acid metabolism and SCFA production by human gut micro-flora grown in an in vitro semi-continuous culture. 2004 Anaerobe pmid:16701496
Gutierrez-Bañuelos H et al. Zoonotic bacterial populations, gut fermentation characteristics and methane production in feedlot steers during oral nitroethane treatment and after the feeding of an experimental chlorate product. 2007 Anaerobe pmid:17208022
Vitali B et al. An in vitro evaluation of the effect of probiotics and prebiotics on the metabolic profile of human microbiota. 2012 Anaerobe pmid:22579985
Turunen K et al. Impact of beta-glucan on the faecal microbiota of polypectomized patients: a pilot study. 2011 Anaerobe pmid:21515398
Shen Q et al. A comparative in vitro investigation into the effects of cooked meats on the human faecal microbiota. 2010 Anaerobe pmid:20934523
Nazzaro F et al. The prebiotic source influences the growth, biochemical features and survival under simulated gastrointestinal conditions of the probiotic Lactobacillus acidophilus. 2012 Anaerobe pmid:22710413
D'Angelis CE et al. Inhibiting effect of Dorstenia asaroides extracts on cariogenic properties of Streptococcus mutans. 2012 Anaerobe pmid:22266301
Purwani EY et al. Fermentation RS3 derived from sago and rice starch with Clostridium butyricum BCC B2571 or Eubacterium rectale DSM 17629. 2012 Anaerobe pmid:21979490
Saengkerdsub S et al. Effects of nitro compounds and feedstuffs on in vitro methane production in chicken cecal contents and rumen fluid. 2006 Anaerobe pmid:16701620
Russell JB Enrichment of fusobacteria from the rumen that can utilize lysine as an energy source for growth. 2005 Anaerobe pmid:16701548
Miltko R et al. Can fungal zoospores be the source of energy for the rumen protozoa Eudiplodinium maggii? 2014 Anaerobe pmid:24012688
Allen-Vercoe E et al. Anaerostipes hadrus comb. nov., a dominant species within the human colonic microbiota; reclassification of Eubacterium hadrum Moore et al. 1976. 2012 Anaerobe pmid:22982042
Connolly ML et al. In vitro evaluation of the microbiota modulation abilities of different sized whole oat grain flakes. 2010 Anaerobe pmid:20624475