butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Gruchlik A et al. Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. Acta Pol Pharm pmid:21229889
Kim JS et al. High-level scu-PA production by butyrate-treated serum-free culture of recombinant CHO cell line. Biotechnol. Prog. pmid:15575713
González-Pajuelo M et al. Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. Metab. Eng. pmid:16095939
Kien CL et al. Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. JPEN J Parenter Enteral Nutr pmid:18165447
Ohata A et al. Short-chain fatty acids alter tight junction permeability in intestinal monolayer cells via lipoxygenase activation. Nutrition pmid:15975492
Roy MJ et al. In vitro studies on the inhibition of colon cancer by butyrate and carnitine. Nutrition pmid:19619983
Nabandith V et al. Inhibitory effects of crude alpha-mangostin, a xanthone derivative, on two different categories of colon preneoplastic lesions induced by 1, 2-dimethylhydrazine in the rat. Asian Pac. J. Cancer Prev. pmid:15546251
Usenko TN et al. [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor]. Mol. Biol. (Mosk.) pmid:12391846
Vester BM et al. Influence of feeding raw or extruded feline diets on nutrient digestibility and nitrogen metabolism of African wildcats (Felis lybica). Zoo Biol. pmid:20095004
Jolly RA et al. Microvesicular steatosis induced by a short chain fatty acid: effects on mitochondrial function and correlation with gene expression. Toxicol Pathol pmid:15503661
Wang Y et al. Sodium butyrate-induced apoptosis and ultrastructural changes in MCF-7 breast cancer cells. Ultrastruct Pathol pmid:27158913
Ibrahim MA Assessment of insulin stability inside diblock copolymer PEG-PLA microspheres. Sci Pharm pmid:21179361
Fathallah H et al. Epigenetic analysis of the human alpha- and beta-globin gene clusters. Blood Cells Mol. Dis. pmid:18029204
Kim J et al. Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. Anticancer Res. pmid:17970072
Lee JS and Lee GM Effect of sodium butyrate on autophagy and apoptosis in Chinese hamster ovary cells. Biotechnol. Prog. pmid:22492702
Becker N et al. Human intestinal microbiota: characterization of a simplified and stable gnotobiotic rat model. Gut Microbes pmid:21637015
Nofrarías M et al. Long-term intake of resistant starch improves colonic mucosal integrity and reduces gut apoptosis and blood immune cells. Nutrition pmid:17936196
Doble MA et al. Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. J. Gastrointest. Surg. pmid:12022991
Soto-Cruz O et al. Modeling of growth, lactate consumption, and volatile fatty acid production by Megasphaera elsdenii cultivated in minimal and complex media. Biotechnol. Prog. pmid:11934285
Cai L et al. Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. J. Environ. Qual. pmid:17215226
Gruchlik A et al. EFFECTS OF 300 mT STATIC MAGNETIC FIELD ON IL-8 SECRETION IN NORMAL HUMAN COLON MYOFIBROBLASTS. Acta Pol Pharm pmid:26647628
Varel VH et al. Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. J. Environ. Qual. pmid:20830936
Sarmiento-Rubiano LA et al. Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. Res. Microbiol. pmid:17825531
Durdux M et al. Fluorescence-based assessment of LRP activity: a comparative study. Anticancer Res. pmid:15161018
Mangian HF and Tappenden KA Butyrate increases GLUT2 mRNA abundance by initiating transcription in Caco2-BBe cells. JPEN J Parenter Enteral Nutr pmid:19892901
Kodama N et al. Induction of myeloperoxidase and nitrotyrosine formation in a human eosinophilic leukemia cell line, EoL-1. Cell Biochem. Funct. pmid:15027099
Fontanellas A et al. Hemoglobin content is increased in the human erythroleukemia K562 cell line by a 56.2-kD peptide from uremic plasma. Am. J. Nephrol. pmid:15024177
Jung JW et al. Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. Antioxid. Redox Signal. pmid:16356138
pmid:16166714
Vester BM et al. Evaluation of nutrient digestibility and fecal characteristics of exotic felids fed horse- or beef-based diets: use of the domestic cat as a model for exotic felids. Zoo Biol. pmid:19830746
Singh NP and Lai HC Synergistic cytotoxicity of artemisinin and sodium butyrate on human cancer cells. Anticancer Res. pmid:16309236
Jeon JH et al. Characterization and its potential application of two esterases derived from the arctic sediment metagenome. Mar. Biotechnol. pmid:18814017
Lea MA et al. Induction of differentiation of colon cancer cells by combined inhibition of kinases and histone deacetylase. Anticancer Res. pmid:17465197
Kien CL et al. Lactulose feeding lowers cecal densities of clostridia in piglets. JPEN J Parenter Enteral Nutr pmid:17463144
Liamleam W and Annachhatre AP Electron donors for biological sulfate reduction. Biotechnol. Adv. pmid:17572039
Karna E et al. The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. Acta Pol Pharm pmid:19719045
Miki Y et al. Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. Anticancer Res. pmid:17595767
Rahman M et al. The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. Oxid Med Cell Longev pmid:20716918
Sung YH et al. Influence of down-regulation of caspase-3 by siRNAs on sodium-butyrate-induced apoptotic cell death of Chinese hamster ovary cells producing thrombopoietin. Metab. Eng. pmid:16169764
Orchel A et al. Influence of sodium butyrate on antioxidative enzymes activity in Caco-2 cell lines. Acta Pol Pharm pmid:17357609
Noble R et al. Olfactory response to mushroom composting emissions as a function of chemical concentration. J. Environ. Qual. pmid:11401265
Nishinaga M et al. Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells. Photochem. Photobiol. pmid:22220555
Hossain Z et al. Growth inhibition and induction of differentiation and apoptosis mediated by sodium butyrate in Caco-2 cells with algal glycolipids. In Vitro Cell. Dev. Biol. Anim. pmid:16153148
Mackie RI et al. Biochemical and microbiological evidence for fermentative digestion in free-living land iguanas (Conolophus pallidus) and marine iguanas (Amblyrhynchus cristatus) on the Galápagos archipelago. Physiol. Biochem. Zool. pmid:15057723
Drozdowski LA et al. Short-chain fatty acids and total parenteral nutrition affect intestinal gene expression. JPEN J Parenter Enteral Nutr pmid:12005453
Lokshina LY et al. Modeling of anaerobic degradation of solid slaughterhouse waste: inhibition effects of long-chain fatty acids or ammonia. Appl. Biochem. Biotechnol. pmid:12794281
Shahbazfar AA et al. A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines. J Cancer Res Ther pmid:25579554
Karna E et al. The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. Acta Pol Pharm pmid:19645322
Tekucheva DN et al. Immobilized purple bacteria for light-driven H2 production from starch and potato fermentation effluents. Biotechnol. Prog. pmid:21751433
Loughrin JH et al. Evaluation of second-generation multistage wastewater treatment system for the removal of malodors from liquid swine waste. J. Environ. Qual. pmid:19549951
Wei ZL et al. Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. Anticancer Res. pmid:18630528
Oh HK et al. Effect of N-Acetylcystein on butyrate-treated Chinese hamster ovary cells to improve the production of recombinant human interferon-beta-1a. Biotechnol. Prog. pmid:16080696
Orchel A et al. Quantification of p21 gene expression in Caco-2 cells treated with sodium butyrate using real-time reverse transcription-PCR (RT-PCR) assay. Acta Pol Pharm pmid:13678314
pmid:
Wang L et al. Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. J. Int. Med. Res. pmid:19589263
Chin HL et al. Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. Biotechnol. Prog. pmid:12675576
Rossi DL et al. A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. Biotechnol. Prog. pmid:21473000
Han L et al. Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. Blood Cells Mol. Dis. pmid:18555711
Kim GH et al. Epigenetic mechanisms of pulmonary hypertension. Pulm Circ pmid:22140624
Cai G et al. Metabolic flux network and analysis of fermentative hydrogen production. Biotechnol. Adv. pmid:21362466
Gassull MA et al. Macronutrients and bioactive molecules: is there a specific role in the management of inflammatory bowel disease? JPEN J Parenter Enteral Nutr pmid:15980281
Taylor AJ and Beck CW Histone deacetylases are required for amphibian tail and limb regeneration but not development. Mech. Dev. pmid:22947425
Wang B et al. Butyrate inhibits functional differentiation of human monocyte-derived dendritic cells. Cell. Immunol. pmid:18522857
Scharlau D et al. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat. Res. pmid:19383551
Ghosh SK et al. Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. Blood Cells Mol. Dis. pmid:17161633
Fang HH et al. Effects of Mo(VI) on phototrophic hydrogen production by Rhodobacter sphaeroides. Environ Technol pmid:21970170
Zhang S et al. Influence of pulsed electric field treatments on the volatile compounds of milk in comparison with pasteurized processing. J. Food Sci. pmid:21535640
Wang Q et al. Characterization of monocarboxylate transport in human kidney HK-2 cells. Mol. Pharm. pmid:17140255
Rodriguez J et al. Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions. Biotechnol. Prog. pmid:15903237
Lim SJ et al. Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. Mol Med Rep pmid:21475856
Hu YC et al. Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. Biotechnol. Prog. pmid:12675574
Bayés M and Rabasseda X Gateways to clinical trials. Methods Find Exp Clin Pharmacol pmid:18389098
Gennari L et al. Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. Phytochem Anal pmid:21337646
Cenkvári E et al. Investigations on the effects of Ca-soap of linseed oil on rumen fermentation in sheep and on milk composition of goats. J Anim Physiol Anim Nutr (Berl) pmid:15787990
Liu L et al. Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. Cell. Immunol. pmid:22698927
Joachimiak R et al. Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. Acta Pol Pharm pmid:18323252
Fathallah H et al. Differences in response to fetal hemoglobin induction therapy in beta-thalassemia and sickle cell disease. Blood Cells Mol. Dis. pmid:19346141
Grebenová D et al. The proteomic study of sodium butyrate antiproliferative/cytodifferentiation effects on K562 cells. Blood Cells Mol. Dis. pmid:16978890
Sandmann G A nitromethane-based HPLC system alternative to acetonitrile for carotenoid analysis of fruit and vegetables. Phytochem Anal pmid:20310077
Sanduja S et al. The roles of TTP and BRF proteins in regulated mRNA decay. Wiley Interdiscip Rev RNA pmid:21278925
Munn AJ et al. Hindgut plasticity in wallabies fed hay either unchopped or ground and pelleted: fiber is not the only factor. Physiol. Biochem. Zool. pmid:19331583
Krokowicz L et al. Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. Travel Med Infect Dis pmid:24063909
Bartholome AL et al. Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation after an 80% jejunoileal resection in neonatal piglets. JPEN J Parenter Enteral Nutr pmid:15291402
pmid:11071567
Bijaya G et al. Synthesis and evaluation of esmolol prodrugs for transdermal delivery. Drug Deliv pmid:20553111
Barker HA et al. The Synthesis of Butyric and Caproic Acids from Ethanol and Acetic Acid by Clostridium Kluyveri. 1945 Proc. Natl. Acad. Sci. U.S.A. pmid:16588706
TOBIE WC and AYRES GB alpha-Hydroxyisobutyric acid buffers (pH 2.3-5.0) not altered in pH by mold growth. 1945 J. Bacteriol. pmid:21005569
VISSCHER FE Renal clearance of beta-hydroxybutyric acid in a dog. 1945 Proc. Soc. Exp. Biol. Med. pmid:21006321
AXELROD AE et al. The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin. 1946 J. Biol. Chem. pmid:20985652
RABE RF Butyric acid and duodenal ulcer. 1946 J Am Inst Homeopath pmid:20988470
WILLIAMSON J and LOURIE EM Interference with the trypanocidal action of gamma-(p-arsenosophenyl) butyric acid by p-aminobenzoic acid. 1946 Ann Trop Med Parasitol pmid:20997909
TOBIE WC and AYRES GB Action of alpha-hydroxyisobutyric acid on micro-organisms. 1946 Nature pmid:21064937
HARTELIUS V and JOHANSEN G The influence of alpha, gamma-dihydroxy-beta, beta-dimethyl-butyric acid on yeast growth. 1946 Cr Trav Lab Carlsberg Ser Physiol pmid:21028375
LIFSON N and LORBER V Pathways of conversion of butyrate carbon to rat liver glycogen. 1947 Fed. Proc. pmid:20342751
MASON LS and ROBINSON AL The heats of dilution of aqueous solutions of four amino butyric acids at 25 degrees. 1947 J. Am. Chem. Soc. pmid:20292475
WALTER M [Not Available]. 1947 Z Vitam Forsch pmid:20296102
Bhat JV and Barker HA Clostridium lacto-acetophilum Nov. Spec. and the Role of Acetic Acid in the Butyric Acid Fermentation of Lactate. 1947 J. Bacteriol. pmid:16561372
ROBERTS S and SZEGO CM The influence of fasting on the peripheral utilization of sodium beta-hydroxybutyrate in the rat. 1947 Fed. Proc. pmid:20244242
LACKEY RW et al. Effect on cardiac glycogen of intravenously administered sodium acetoacetate, sodium beta-hydroxybutyrate and sodium butyrate. 1947 Proc. Soc. Exp. Biol. Med. pmid:18921782
CLARK FM and DEHR A A study of butyric acid-producing anaerobes isolated from spoiled canned tomatoes. 1947 Mar-Apr Food Res pmid:20294337