| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Tumor Virus Infections | D014412 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Gruchlik A et al. | Influence of troglitazone, sodium butyrate, 5-aminosalicylic acid and BAY 11-7082 on the chemokine ENA-78/CXCL5 secretion in the intestinal subepithelial myofibroblasts. | Acta Pol Pharm | pmid:21229889 | |
| González-Pajuelo M et al. | Metabolic engineering of Clostridium acetobutylicum for the industrial production of 1,3-propanediol from glycerol. | Metab. Eng. | pmid:16095939 | |
| Kien CL et al. | Effects of the in vivo supply of butyrate on histone acetylation of cecum in piglets. | JPEN J Parenter Enteral Nutr | pmid:18165447 | |
| Usenko TN et al. | [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor]. | Mol. Biol. (Mosk.) | pmid:12391846 | |
| Fathallah H et al. | Epigenetic analysis of the human alpha- and beta-globin gene clusters. | Blood Cells Mol. Dis. | pmid:18029204 | |
| Kim J et al. | Sodium butyrate regulates androgen receptor expression and cell cycle arrest in human prostate cancer cells. | Anticancer Res. | pmid:17970072 | |
| Doble MA et al. | Luminal regulation of Na(+)/H(+) exchanger gene expression in rat ileal mucosa. | J. Gastrointest. Surg. | pmid:12022991 | |
| Cai L et al. | Evaluation of zeolite for control of odorants emissions from simulated poultry manure storage. | J. Environ. Qual. | pmid:17215226 | |
| Varel VH et al. | Manure odor potential and Escherichia coli concentrations in manure slurries of feedlot steers fed 40% corn wet distillers grains. | J. Environ. Qual. | pmid:20830936 | |
| Sarmiento-Rubiano LA et al. | Dietary supplementation with sorbitol results in selective enrichment of lactobacilli in rat intestine. | Res. Microbiol. | pmid:17825531 | |
| Durdux M et al. | Fluorescence-based assessment of LRP activity: a comparative study. | Anticancer Res. | pmid:15161018 | |
| Jung JW et al. | Augmentation of sodium butyrate-induced apoptosis by p38 MAP kinase inhibition in rat liver epithelial cells. | Antioxid. Redox Signal. | pmid:16356138 | |
| Liamleam W and Annachhatre AP | Electron donors for biological sulfate reduction. | Biotechnol. Adv. | pmid:17572039 | |
| Miki Y et al. | Butyrate inhibits oral cancer cell proliferation and regulates expression of secretory phospholipase A2-X and COX-2. | Anticancer Res. | pmid:17595767 | |
| Rahman M et al. | The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet. | Oxid Med Cell Longev | pmid:20716918 | |
| Shahbazfar AA et al. | A survey on anticancer effects of artemisinin, iron, miconazole, and butyric acid on 5637 (bladder cancer) and 4T1 (Breast cancer) cell lines. | J Cancer Res Ther | pmid:25579554 | |
| Karna E et al. | The mechanism of butyrate-induced collagen biosynthesis in cultured fibroblasts. | Acta Pol Pharm | pmid:19645322 | |
| Wei ZL et al. | Enhancement of sodium butyrate-induced cell death by hyperthermia in HCT 116 human colorectal cancer cells. | Anticancer Res. | pmid:18630528 | |
| Wang L et al. | Sodium butyrate induces human colon carcinoma HT-29 cell apoptosis through a mitochondrial pathway. | J. Int. Med. Res. | pmid:19589263 | |
| Chin HL et al. | Fedbatch operation using Clostridium acetobutylicum suspension culture as biocatalyst for enhancing hydrogen production. | Biotechnol. Prog. | pmid:12675576 | |
| Rossi DL et al. | A new mammalian host cell with enhanced survival enables completely serum-free development of high-level protein production cell lines. | Biotechnol. Prog. | pmid:21473000 | |
| Han L et al. | Sodium butyrate activates erythroid-specific 5-aminolevulinate synthase gene through Sp1 elements at its promoter. | Blood Cells Mol. Dis. | pmid:18555711 | |
| Kim GH et al. | Epigenetic mechanisms of pulmonary hypertension. | Pulm Circ | pmid:22140624 | |
| Cai G et al. | Metabolic flux network and analysis of fermentative hydrogen production. | Biotechnol. Adv. | pmid:21362466 | |
| Taylor AJ and Beck CW | Histone deacetylases are required for amphibian tail and limb regeneration but not development. | Mech. Dev. | pmid:22947425 | |
| Ghosh SK et al. | Short, discontinuous exposure to butyrate effectively sensitizes latently EBV-infected lymphoma cells to nucleoside analogue antiviral agents. | Blood Cells Mol. Dis. | pmid:17161633 | |
| Rodriguez J et al. | Enhanced production of monomeric interferon-beta by CHO cells through the control of culture conditions. | Biotechnol. Prog. | pmid:15903237 | |
| Lim SJ et al. | Effect of butyrate on the heregulin/ErbB-mediated proliferation of human colorectal cancer cells. | Mol Med Rep | pmid:21475856 | |
| Hu YC et al. | Enhancement and prolongation of baculovirus-mediated expression in mammalian cells: focuses on strategic infection and feeding. | Biotechnol. Prog. | pmid:12675574 | |
| Bayés M and Rabasseda X | Gateways to clinical trials. | Methods Find Exp Clin Pharmacol | pmid:18389098 | |
| Gennari L et al. | Total extract of Beta vulgaris var. cicla seeds versus its purified phenolic components: antioxidant activities and antiproliferative effects against colon cancer cells. | Phytochem Anal | pmid:21337646 | |
| Liu L et al. | Butyrate interferes with the differentiation and function of human monocyte-derived dendritic cells. | Cell. Immunol. | pmid:22698927 | |
| Joachimiak R et al. | Influence of sodium butyrate on hepatocellular carcinoma (hepG2) and glioblastoma (C6) cell lines in vitro. | Acta Pol Pharm | pmid:18323252 | |
| Krokowicz L et al. | Sodium butyrate and short chain fatty acids in prevention of travellers' diarrhoea: a randomized prospective study. | Travel Med Infect Dis | pmid:24063909 | |
| pmid:11071567 | ||||
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| AXELROD AE et al. | The differential effect of biotin sulfone and gamma-(3,4-ureylenecyclohexyl) butyric acid upon the microbiological activity of biotin and oxybiotin. | 1946 | J. Biol. Chem. | pmid:20985652 |
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| CLARK FM and DEHR A | A study of butyric acid-producing anaerobes isolated from spoiled canned tomatoes. | 1947 Mar-Apr | Food Res | pmid:20294337 |