| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hemolysis | D006461 | 131 associated lipids |
| Uremia | D014511 | 33 associated lipids |
| Colitis, Ulcerative | D003093 | 24 associated lipids |
| Kidney Failure, Chronic | D007676 | 51 associated lipids |
| Diarrhea | D003967 | 32 associated lipids |
| Diabetes Mellitus | D003920 | 90 associated lipids |
| Arrhythmias, Cardiac | D001145 | 42 associated lipids |
| Neovascularization, Pathologic | D009389 | 39 associated lipids |
| Tumor Virus Infections | D014412 | 8 associated lipids |
| Adenocarcinoma | D000230 | 166 associated lipids |
butyric acid
butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.
Cross Reference
Introduction
To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with butyric acid?
butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
Loading... please refresh the page if content is not showing up.
Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with butyric acid
PubChem Associated disorders and diseases
What pathways are associated with butyric acid
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with butyric acid?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What functions are associated with butyric acid?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with butyric acid?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
Loading... please refresh the page if content is not showing up.
What genes are associated with butyric acid?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with butyric acid?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with butyric acid
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Nicholas J et al. | A single 13-kilobase divergent locus in the Kaposi sarcoma-associated herpesvirus (human herpesvirus 8) genome contains nine open reading frames that are homologous to or related to cellular proteins. | 1997 | J. Virol. | pmid:9032328 |
| Brun T et al. | Long-chain fatty acids inhibit acetyl-CoA carboxylase gene expression in the pancreatic beta-cell line INS-1. | 1997 | Diabetes | pmid:9032094 |
| Hersey SJ | Metabolic changes associated with gastric stimulation. | 1977 | Gastroenterology | pmid:902957 |
| Doreau M and Ottou JF | Influence of niacin supplementation on in vivo digestibility and ruminal digestion in dairy cows. | 1996 | J. Dairy Sci. | pmid:9029363 |
| Oster T et al. | Gene transfer technologies for the production of enzyme and protein reference materials. | 1997 | Clin. Chim. Acta | pmid:9028623 |
| Higgins PJ et al. | P52PAI-1 gene expression in butyrate-induced flat revertants of v-ras-transformed rat kidney cells: mechanism of induction and involvement in the morphological response. | 1997 | Biochem. J. | pmid:9020877 |
| Ishiguro K and Sartorelli AC | The response of IL-3 dependent B6SUtA bone marrow cells to both erythropoietin and chemical inducers of differentiation. | 1996 | Cancer Lett. | pmid:9018107 |
| Hales RH | Gas-permeable cellulose acetate butyrate (CAB) contact lenses. | 1977 | Ann Ophthalmol | pmid:900727 |
| Rabizadeh E et al. | Esterase inhibitors diminish the modulation of gene expression by butyric acid derivative, pivaloyloxymethyl butyrate (AN-9). | 1996 | Isr. J. Med. Sci. | pmid:9007151 |
| Hague A et al. | The role of butyrate in human colonic epithelial cells: an energy source or inducer of differentiation and apoptosis? | 1996 | Proc Nutr Soc | pmid:9004335 |
| Götzinger N et al. | Regulation of human endogenous retrovirus-K Gag expression in teratocarcinoma cell lines and human tumours. | 1996 | J. Gen. Virol. | pmid:9000088 |
| Plaisancié P et al. | Luminal peptide YY-releasing factors in the isolated vascularly perfused rat colon. | 1996 | J. Endocrinol. | pmid:8994387 |
| Chacin J et al. | Role of oxalacetate in lipoate effect on frog gastric mucosa. | 1976 | Am. J. Physiol. | pmid:8990 |
| Immig I et al. | Attempts to induce reductive acetogenesis into a sheep rumen. | 1996 | Arch Tierernahr | pmid:8988318 |
| Forster RJ et al. | 16S rDNA analysis of Butyrivibrio fibrisolvens: phylogenetic position and relation to butyrate-producing anaerobic bacteria from the rumen of white-tailed deer. | 1996 | Lett. Appl. Microbiol. | pmid:8987694 |
| Miller G et al. | Selective switch between latency and lytic replication of Kaposi's sarcoma herpesvirus and Epstein-Barr virus in dually infected body cavity lymphoma cells. | 1997 | J. Virol. | pmid:8985352 |
| Li S et al. | The C-terminal Src kinase (Csk) is widely expressed, active in HT-29 cells that contain activated Src, and its expression is downregulated in butyrate-treated SW620 cells. | 1996 | Cell Biol. Int. | pmid:8979366 |
| D'Argenio G et al. | Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model. | 1996 | Gastroenterology | pmid:8964397 |
| Böhmig GA et al. | Induction of alloantigen-specific hyporesponsiveness in vitro by n-butyrate: antagonistic effect of cyclosporin A. | 1996 | Transpl. Int. | pmid:8959855 |
| Buckley AR et al. | Alterations in pim-1 and c-myc expression associated with sodium butyrate-induced growth factor dependency in autonomous rat Nb2 lymphoma cells. | 1996 | Cell Growth Differ. | pmid:8959340 |
| Benoit NE and Wade WF | Increased inhibition of proliferation of human B cell lymphomas following ligation of CD40, and either CD19, CD20, CD95 or surface immunoglobulin. | 1996 | Immunopharmacology | pmid:8956976 |
| Lallemand F et al. | Direct inhibition of the expression of cyclin D1 gene by sodium butyrate. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8954100 |
| Morrone G et al. | Differential regulation of the expression of interleukin-2 receptor gamma-chain during the in vitro differentiation of human myeloid cells. | 1995 | Biochem. J. | pmid:8948450 |
| MacCormac LP and Grundy JE | Human cytomegalovirus induces an Fc gamma receptor (Fc gammaR) in endothelial cells and fibroblasts that is distinct from the human cellular Fc gammaRs. | 1996 | J. Infect. Dis. | pmid:8940203 |
| Tada S et al. | Reduction of LAK-sensitivity and changes in antigen expression on hepatoma cells by sodium butyrate. | 1996 | Cancer Biochem. Biophys. | pmid:8937741 |
| Fiorino AS and Zvibel I | Disruption of cell-cell adhesion in the presence of sodium butyrate activates expression of the 92 kDa type IV collagenase in MDCK cells. | 1996 | Cell Biol. Int. | pmid:8931316 |
| Mondal D and Agrawal KC | Effect of HIV type 1 Tat protein on butyric acid-induced differentiation in a hematopoietic progenitor cell line. | 1996 | AIDS Res. Hum. Retroviruses | pmid:8911578 |
| Hanski C et al. | Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue. | 1996 | Glycoconj. J. | pmid:8909999 |
| Grdisa M and White MK | Expression of glyceraldehyde-3-phosphate dehydrogenase during differentiation of HD3 cells. | 1996 | Eur. J. Cell Biol. | pmid:8905295 |
| Campbell CG et al. | Efficiency of D- vs L-methionine utilization by growing steers. | 1996 | J. Anim. Sci. | pmid:8904718 |
| Steinhart AH et al. | Treatment of left-sided ulcerative colitis with butyrate enemas: a controlled trial. | 1996 | Aliment. Pharmacol. Ther. | pmid:8899080 |
| Nordgaard I et al. | Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fibre (Plantago ovata seeds). | 1996 | Scand. J. Gastroenterol. | pmid:8898423 |
| Lee E et al. | Involvement of histone hyperacetylation in triggering DNA fragmentation of rat thymocytes undergoing apoptosis. | 1996 | FEBS Lett. | pmid:8898091 |
| Frazier DP et al. | Identification of cis-acting sequences in the promoter of the herpes simplex virus type 1 latency-associated transcripts required for activation by nerve growth factor and sodium butyrate in PC12 cells. | 1996 | J. Virol. | pmid:8892861 |
| Frazier DP et al. | The herpes simplex virus type 1 latency-associated transcript promoter is activated through Ras and Raf by nerve growth factor and sodium butyrate in PC12 cells. | 1996 | J. Virol. | pmid:8892860 |
| Treem WR et al. | Fecal short-chain fatty acids in patients with diarrhea-predominant irritable bowel syndrome: in vitro studies of carbohydrate fermentation. | 1996 | J. Pediatr. Gastroenterol. Nutr. | pmid:8890079 |
| Thomas GL et al. | Enhanced apoptosis in transformed human lung fibroblasts after exposure to sodium butyrate. | 1996 | In Vitro Cell. Dev. Biol. Anim. | pmid:8889605 |
| Siavoshian S et al. | Butyrate enhances major histocompatibility complex class I, HLA-DR and ICAM-1 antigen expression on differentiated human intestinal epithelial cells. | 1996 | Eur. J. Clin. Invest. | pmid:8889444 |
| Basson MD et al. | Regulation of human colonic cell line proliferation and phenotype by sodium butyrate. | 1996 | Dig. Dis. Sci. | pmid:8888712 |
| Seki J et al. | Dimethyl sulfoxide and related polar compounds enhance infection of human T cells with HIV-1 in vitro. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8886001 |
| Sandvig K et al. | Importance of glycolipid synthesis for butyric acid-induced sensitization to shiga toxin and intracellular sorting of toxin in A431 cells. | 1996 | Mol. Biol. Cell | pmid:8885234 |
| Rogers KM and Barnsley EA | The metabolism of S-carboxyalkylcysteines in man. | 1977 | Xenobiotica | pmid:888445 |
| Nakai T et al. | 1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes. | 1996 | Acad Radiol | pmid:8883515 |
| Roediger WE et al. | Methionine derivatives diminish sulphide damage to colonocytes--implications for ulcerative colitis. | 1996 | Gut | pmid:8881814 |
| Nosbush BB et al. | Effect of concentrate source and amount in diets on plasma hormone concentrations of prepubertal heifers. | 1996 | J. Dairy Sci. | pmid:8880464 |
| Moulding DA et al. | Modulation of neutrophil apoptosis by pharmacological agents. | 1996 | Biochem. Soc. Trans. | pmid:8879036 |
| Sun R et al. | Polyadenylylated nuclear RNA encoded by Kaposi sarcoma-associated herpesvirus. | 1996 | Proc. Natl. Acad. Sci. U.S.A. | pmid:8876232 |
| Ohbo M et al. | Effects of saturated fatty acids on amylase release from exocrine pancreatic segments of sheep, rats, hamsters, field voles and mice. | 1996 | J. Comp. Physiol. B, Biochem. Syst. Environ. Physiol. | pmid:8870261 |
| Uthayakumar S and Granger BL | Cell surface accumulation of overexpressed hamster lysosomal membrane glycoproteins. | 1995 | Cell. Mol. Biol. Res. | pmid:8867788 |
| Egawa N et al. | Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: a morphological and molecular analysis of four cell lines. | 1996 | Virchows Arch. | pmid:8865855 |
| Velázquez OC et al. | In vivo crypt surface hyperproliferation is decreased by butyrate and increased by deoxycholate in normal rat colon: associated in vivo effects on c-Fos and c-Jun expression. | 1996 Jul-Aug | JPEN J Parenter Enteral Nutr | pmid:8865104 |
| Tiedge M and Lenzen S | Effects of sodium butyrate on glucose transporter and glucose-phosphorylating enzyme gene expression in RINm5F insulinoma cells. | 1996 | J. Mol. Endocrinol. | pmid:8863183 |
| Harig JM et al. | Transport of n-butyrate into human colonic luminal membrane vesicles. | 1996 | Am. J. Physiol. | pmid:8843764 |
| Whitelaw E and Williamson DH | Effects of lactation of ketogenesis from oleate or butyrate in rat hepatocytes. | 1977 | Biochem. J. | pmid:883950 |
| Mandal M and Kumar R | Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. | 1996 | Cell Growth Differ. | pmid:8838861 |
| Recht LD et al. | Immunotoxin sensitivity of Chinese hamster ovary cells expressing human transferrin receptors with differing internalization rates. | 1996 | Cancer Immunol. Immunother. | pmid:8830739 |
| Yamamoto I et al. | Histone hyperacetylation plays a role in augmentation of IL-4-induced IgE production in LPS-stimulated murine B-lymphocytes by sodium butyrate. | 1996 | J. Biochem. | pmid:8827437 |
| Vaziri C et al. | Expression of the aryl hydrocarbon receptor is regulated by serum and mitogenic growth factors in murine 3T3 fibroblasts. | 1996 | J. Biol. Chem. | pmid:8824226 |
| Fukamauchi F et al. | Differential effects of butyrate and dibutyryl cAMP on mRNA levels of muscarinic acetylcholine receptor subtypes expressed in neurohybrid cell lines. | 1996 | Neurosci. Lett. | pmid:8823760 |
| Peldszus S et al. | Determination of short-chain aliphatic, oxo- and hydroxy-acids in drinking water at low microgram per liter concentrations. | 1996 | J Chromatogr A | pmid:8819819 |
| Horiuchi A and Felder RA | High-level expression of rat D1A dopamine receptor cDNA in mouse fibroblast LTK- cells by n-butyrate. | 1996 | Clin. Exp. Pharmacol. Physiol. | pmid:8819644 |
| Kendall PE and McLeay LM | Excitatory effects of volatile fatty acids on the in vitro motility of the rumen of sheep. | 1996 | Res. Vet. Sci. | pmid:8819185 |
| Lindner H et al. | Separation of acetylated core histones by hydrophilic-interaction liquid chromatography. | 1996 | J Chromatogr A | pmid:8817877 |
| Wasserman LM et al. | cAMP effects on myogenic gene expression in rhabdomyosarcoma cells. | 1996 | Exp. Cell Res. | pmid:8806451 |
| Chireux M et al. | Histone hyperacetylating agents stimulate promoter activity of human choline acetyltransferase gene in transfection experiment. | 1996 | Brain Res. Mol. Brain Res. | pmid:8804715 |
| Welters CF et al. | Supplementation of enteral nutrition with butyrate leads to increased portal efflux of amino acids in growing pigs with short bowel syndrome. | 1996 | J. Pediatr. Surg. | pmid:8801305 |
| Kopf MA et al. | Key role of alkanoic acids on the spectral properties, activity, and active-site stability of iron-containing nitrile hydratase from Brevibacterium R312. | 1996 | Eur. J. Biochem. | pmid:8797859 |
| Keane MM et al. | The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells. | 1996 | Cancer Res. | pmid:8797598 |
| Miettinen H and Huhtanen P | Effects of the ratio of ruminal propionate to butyrate on milk yield and blood metabolites in dairy cows. | 1996 | J. Dairy Sci. | pmid:8792285 |
| Aaronson PI et al. | Mechanism of butyrate-induced vasorelaxation of rat mesenteric resistance artery. | 1996 | Br. J. Pharmacol. | pmid:8789392 |
| Rottleb C et al. | Structure-activity relationship of 17 structural analogues of n-butyric acid upon c-myc expression. | 1996 | Int. J. Cancer | pmid:8782665 |
| McBain JA et al. | Phorbol ester augments butyrate-induced apoptosis of colon cancer cells. | 1996 | Int. J. Cancer | pmid:8782664 |
| Feng P et al. | Sodium butyrate is a potent modulator of smooth muscle cell proliferation and gene expression. | 1996 | Cell Prolif. | pmid:8782486 |
| Taggart MJ et al. | Stimulus-dependent modulation of smooth muscle intracellular calcium and force by altered intracellular pH. | 1996 | Pflugers Arch. | pmid:8772130 |
| Dagher PC et al. | Dissociation of colonic apical Na/H exchange activity from bulk cytoplasmic pH. | 1996 | Am. J. Physiol. | pmid:8764164 |
| Ghosh NK and Cox RP | Induction of human follicle-stimulating hormone in HeLa cells by sodium butyrate. | 1977 | Nature | pmid:876359 |
| Goto I et al. | Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. | 1996 | Br. J. Cancer | pmid:8761368 |
| Acheson DW et al. | Translocation of Shiga toxin across polarized intestinal cells in tissue culture. | 1996 | Infect. Immun. | pmid:8757867 |
| Ogryzko VV et al. | Human fibroblast commitment to a senescence-like state in response to histone deacetylase inhibitors is cell cycle dependent. | 1996 | Mol. Cell. Biol. | pmid:8756678 |
| Velázquez OC et al. | Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice. | 1996 | Surgery | pmid:8751616 |
| Cheng G et al. | [Isolation and reassociation of acetogen and methanogen in a syntrophobic coculture degrading butyrate anaerobically]. | 1995 | Wei Sheng Wu Xue Bao | pmid:8745550 |
| Diener M et al. | Neuronally mediated anion secretion induced by short-chain fatty acids in the rat distal small intestine. | 1996 | Acta Physiol. Scand. | pmid:8735652 |
| Hodin RA et al. | Cellular growth state differentially regulates enterocyte gene expression in butyrate-treated HT-29 cells. | 1996 | Cell Growth Differ. | pmid:8732674 |
| Madesh M et al. | Butyrate-induced alteration in lipid composition of human colon cell line HT-29. | 1996 | Biochem. Mol. Biol. Int. | pmid:8728094 |
| Adams FS et al. | Characterization and transplantation of two neuronal cell lines with dopaminergic properties. | 1996 | Neurochem. Res. | pmid:8726972 |
| Eftimiadi C et al. | Butyric acid, a metabolic end product of anaerobic bacteria, inhibits B-lymphocyte function. | 1995 | Minerva Stomatol | pmid:8721203 |
| Olivieri NF | Reactivation of fetal hemoglobin in patients with beta-thalassemia. | 1996 | Semin. Hematol. | pmid:8714583 |
| Rivero JA and Adunyah SE | Sodium butyrate induces tyrosine phosphorylation and activation of MAP kinase (ERK-1) in human K562 cells. | 1996 | Biochem. Biophys. Res. Commun. | pmid:8713125 |
| Sharma JP et al. | Reversed-phase high-performance liquid chromatographic determination of tetracyclines in urine and plasma. | 1977 | J. Chromatogr. | pmid:870510 |
| Rafferty SP et al. | Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line. | 1996 | Blood | pmid:8704216 |
| Park C et al. | Differential expression and butyrate response of human alkaline phosphatase genes are mediated by upstream DNA elements. | 1996 | Biochemistry | pmid:8703954 |
| Whiteley LO et al. | Evaluation in rats of the dose-response relationship among colonic mucosal growth, colonic fermentation, and dietary fiber. | 1996 | Dig. Dis. Sci. | pmid:8689925 |
| Stein J et al. | Induction of glutathione-S-transferase-pi by short-chain fatty acids in the intestinal cell line Caco-2. | 1996 | Eur. J. Clin. Invest. | pmid:8682162 |
| Velázquez OC et al. | Butyrate and the colonocyte. Implications for neoplasia. | 1996 | Dig. Dis. Sci. | pmid:8674394 |
| McIntosh GH et al. | A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats. | 1996 | J. Gastroenterol. Hepatol. | pmid:8672754 |
| Wiechmann AF | Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation. | 1996 | J. Neurochem. | pmid:8666979 |
| Smith TJ et al. | n-Butyrate induces plasminogen activator inhibitor type 1 messenger RNA in cultured Hep G2 cells. | 1996 | Hepatology | pmid:8666343 |
| Vettese-Dadey M et al. | Acetylation of histone H4 plays a primary role in enhancing transcription factor binding to nucleosomal DNA in vitro. | 1996 | EMBO J. | pmid:8665858 |
| Evtodienko VY et al. | Effect of the alkyl chain length of monocarboxylic acid on the permeation through bilayer lipid membranes. | 1996 | Biochim. Biophys. Acta | pmid:8664324 |
| Lin MC et al. | Reduction of GTP activation of adenylate cyclase system by its coupling to hormone receptor. | 1979 | J. Biol. Chem. | pmid:86543 |