butyric acid

butyric acid is a lipid of Fatty Acyls (FA) class. Butyric acid is associated with abnormalities such as PARKINSON DISEASE, LATE-ONSET, Colitis, Autoimmune Diseases, Inflammatory Bowel Diseases and PARAGANGLIOMAS 2. The involved functions are known as DNA Methylation, Transcription, Genetic, chromatin modification, Gene Expression and Gene Silencing. Butyric acid often locates in Membrane, Chromatin Structure, Chromosomes, viral nucleocapsid location and Ribosomes. The associated genes with butyric acid are Locus, Genes, Dominant, Genes, rRNA, Genome and Chromatin. The related lipids are Butyrates, butyrate, Promega, Butyric Acids and Butyric Acid.

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Introduction

To understand associated biological information of butyric acid, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with butyric acid?

butyric acid is suspected in Colitis, Ulcerative Colitis, Anemia, Sickle Cell, Thalassemia, PARKINSON DISEASE, LATE-ONSET, Infection and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with butyric acid

MeSH term MeSH ID Detail
Hemolysis D006461 131 associated lipids
Uremia D014511 33 associated lipids
Colitis, Ulcerative D003093 24 associated lipids
Kidney Failure, Chronic D007676 51 associated lipids
Diarrhea D003967 32 associated lipids
Diabetes Mellitus D003920 90 associated lipids
Arrhythmias, Cardiac D001145 42 associated lipids
Neovascularization, Pathologic D009389 39 associated lipids
Tumor Virus Infections D014412 8 associated lipids
Adenocarcinoma D000230 166 associated lipids
Per page 10 20 50 100 | Total 149

PubChem Associated disorders and diseases

What pathways are associated with butyric acid

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with butyric acid?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with butyric acid?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with butyric acid?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with butyric acid?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with butyric acid?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with butyric acid

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Authors Title Published Journal PubMed Link
Lee IH et al. Involvement of CCAAT/enhancer-binding protein alpha in haptoglobin gene expression by all-trans-retinoic acid. 2002 Biochem. Biophys. Res. Commun. pmid:12074569
Jørgensen JR et al. Absorption and metabolism of octanoate by the rat colon in vivo: concentration dependency and influence of alternative fuels. 2002 Gut pmid:12077096
Lane MA et al. Developmental changes in ketogenic enzyme gene expression during sheep rumen development. 2002 J. Anim. Sci. pmid:12078735
Iwai M et al. Investigation of parenchymal cell differentiation in organotypic slice culture of mouse fetal liver under administration of sodium butyrate. 2002 Cell Biol. Toxicol. pmid:12083421
Leschelle X et al. Isolation of pig colonic crypts for cytotoxic assay of luminal compounds: effects of hydrogen sulfide, ammonia, and deoxycholic acid. 2002 Cell Biol. Toxicol. pmid:12083425
Salucci M et al. Flavonoids uptake and their effect on cell cycle of human colon adenocarcinoma cells (Caco2). 2002 Br. J. Cancer pmid:12085217
Schwiertz A et al. Anaerostipes caccae gen. nov., sp. nov., a new saccharolytic, acetate-utilising, butyrate-producing bacterium from human faeces. 2002 Syst. Appl. Microbiol. pmid:12086188
Scholz-Ahrens KE and Schrezenmeir J Inulin, oligofructose and mineral metabolism - experimental data and mechanism. 2002 Br. J. Nutr. pmid:12088516
Nagel G et al. Channelrhodopsin-1: a light-gated proton channel in green algae. 2002 Science pmid:12089443
Shiga K et al. Ingestion of water-soluble soybean fiber improves gastrectomy-induced calcium malabsorption and osteopenia in rats. 2002 Jul-Aug Nutrition pmid:12093445
Gil Ede S et al. Electrochemical evaluation of rhodium dimer-DNA interactions. 2002 J Pharm Biomed Anal pmid:12093486
Ebert MN et al. Butyrate induces glutathione S-transferase in human colon cells and protects from genetic damage by 4-hydroxy-2-nonenal. 2001 Nutr Cancer pmid:12094619
Chakeredza S et al. Ruminal fermentation kinetics in ewes offered a maize stover basal diet supplemented with cowpea hay, groundnut hay, cotton seed meal or maize meal. 2002 Trop Anim Health Prod pmid:12094677
Koyama K et al. Metabolism of short chain fatty acid in rat liver in biliary obstruction. 1975 Tohoku J. Exp. Med. pmid:1209614
Guan Y et al. Cloning and expression of the rabbit prostaglandin EP2 receptor. 2002 BMC Pharmacol. pmid:12097143
Denton AS et al. Systematic review for non-surgical interventions for the management of late radiation proctitis. 2002 Br. J. Cancer pmid:12107832
Pedersen NR et al. Effect of fatty acid chain length on initial reaction rates and regioselectivity of lipase-catalysed esterification of disaccharides. 2002 Carbohydr. Res. pmid:12110192
Gálfi P et al. Na+/H+ exchange in primary, secondary and n-butyrate-treated cultures of ruminal epithelial cells: short communication. 2002 Acta Vet. Hung. pmid:12113176
Patnaik A et al. A phase I study of pivaloyloxymethyl butyrate, a prodrug of the differentiating agent butyric acid, in patients with advanced solid malignancies. 2002 Clin. Cancer Res. pmid:12114414
Hu Y et al. The colonic response to genotoxic carcinogens in the rat: regulation by dietary fibre. 2002 Carcinogenesis pmid:12117770
Qualtrough D et al. Expression of CDX2 in normal and neoplastic human colon tissue and during differentiation of an in vitro model system. 2002 Gut pmid:12117877
Harris JI et al. Molecular mediators of Porphyromonas gingivalis-induced T-cell apoptosis. 2002 Oral Microbiol. Immunol. pmid:12121472
Marcil V et al. Modulation of lipid synthesis, apolipoprotein biogenesis, and lipoprotein assembly by butyrate. 2002 Am. J. Physiol. Gastrointest. Liver Physiol. pmid:12121881
Mikkelsen IM et al. Activation of the gamma-glutamyltransferase promoter 2 in the rat colon carcinoma cell line CC531 by histone deacetylase inhibitors is mediated through the Sp1 binding motif. 2002 Biochem. Pharmacol. pmid:12123752
Puppo F et al. Cell-line specific chromatin acetylation at the Sox10-Pax3 enhancer site modulates the RET proto-oncogene expression. 2002 FEBS Lett. pmid:12123817
NaziroÄŸlu M et al. Effect of vitamin E on ruminal fermentation in vitro. 2002 J Vet Med A Physiol Pathol Clin Med pmid:12126139
Gao HJ et al. Enhanced production of D-(-)-3-hydroxybutyric acid by recombinant Escherichia coli. 2002 FEMS Microbiol. Lett. pmid:12127489
Jing Y et al. Targeted removal of PML-RARalpha protein is required prior to inhibition of histone deacetylase for overcoming all-trans retinoic acid differentiation resistance in acute promyelocytic leukemia. 2002 Blood pmid:12130515
Menzel T et al. Butyrate and aspirin in combination have an enhanced effect on apoptosis in human colorectal cancer cells. 2002 Eur. J. Cancer Prev. pmid:12131661
Czyz M et al. GATA-1 binding to the alphaV promoter negatively regulates expression of the integrin alphaV subunit in human leukemic K562 cells. 2002 Acta Biochim. Pol. pmid:12136940
Dzierzewicz Z et al. Changes in the cellular behaviour of human colonic cell line Caco-2 in response to butyrate treatment. 2002 Acta Biochim. Pol. pmid:12136943
Cibis E et al. Biodegradation of potato slops from a rural distillery by thermophilic aerobic bacteria. 2002 Bioresour. Technol. pmid:12146644
Redmond AJ et al. Selective activation of the A10, but not A9, dopamine neurons in the rat by the predator odor, 2,5-dihydro-2,4,5-trimethylthiazoline. 2002 Neurosci. Lett. pmid:12147308
Cushman M et al. Design, synthesis, and evaluation of 6-carboxyalkyl and 6-phosphonoxyalkyl derivatives of 7-oxo-8-ribitylaminolumazines as inhibitors of riboflavin synthase and lumazine synthase. 2002 J. Org. Chem. pmid:12153285
Jackson SK et al. The ability of antigen, but not interleukin-2, to promote n-butyrate-induced T helper 1 cell anergy is associated with increased expression and altered association patterns of cyclin-dependent kinase inhibitors. 2002 Immunology pmid:12153511
Bamba T et al. A new prebiotic from germinated barley for nutraceutical treatment of ulcerative colitis. 2002 J. Gastroenterol. Hepatol. pmid:12164955
Hidalgo MD and García-Encina PA Biofilm development and bed segregation in a methanogenic fluidized bed reactor. 2002 Water Res. pmid:12171407
Wang X et al. Manipulation of colonic bacteria and volatile fatty acid production by dietary high amylose maize (amylomaize) starch granules. 2002 J. Appl. Microbiol. pmid:12174036
Playle LC et al. Abrogation of the radiation-induced G2 checkpoint by the staurosporine derivative UCN-01 is associated with radiosensitisation in a subset of colorectal tumour cell lines. 2002 Br. J. Cancer pmid:12177808
Turner ND et al. Oncogenic ras alters sensitivity of mouse colonocytes to butyrate and fatty acid mediated growth arrest and apoptosis. 2002 Cancer Lett. pmid:12183072
Lee MN et al. Hepatitis C virus core protein represses the p21 promoter through inhibition of a TGF-beta pathway. 2002 J. Gen. Virol. pmid:12185267
Lalman J and Bagley DM Effects of C18 long chain fatty acids on glucose, butyrate and hydrogen degradation. 2002 Water Res. pmid:12188129
Gan SH et al. Correlation of tramadol pharmacokinetics and CYP2D6*10 genotype in Malaysian subjects. 2002 J Pharm Biomed Anal pmid:12191703
Luciano L et al. Massive apoptosis of colonocytes induced by butyrate deprivation overloads resident macrophages and promotes the recruitment of circulating monocytes. 2002 Cell Tissue Res. pmid:12195296
Nayak P and Chatterjee AK Response of regional brain glutamate transaminases of rat to aluminum in protein malnutrition. 2002 BMC Neurosci pmid:12197946
Stoecklin G et al. Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover. 2002 EMBO J. pmid:12198173
Akalin AS et al. Variation in organic acids content during ripening of pickled white cheese. 2002 J. Dairy Sci. pmid:12201516
Broderick GA et al. Efficacy of carbohydrate sources for milk production by cows fed diets based on alfalfa silage. 2002 J. Dairy Sci. pmid:12201528
Mackus WJ et al. Prevention of B cell antigen receptor-induced apoptosis by ligation of CD40 occurs downstream of cell cycle regulation. 2002 Int. Immunol. pmid:12202395
Kalina U et al. Enhanced production of IL-18 in butyrate-treated intestinal epithelium by stimulation of the proximal promoter region. 2002 Eur. J. Immunol. pmid:12207348
Kristensen NB et al. Metabolism of propionate and 1,2-propanediol absorbed from the washed reticulorumen of lactating cows. 2002 J. Anim. Sci. pmid:12211387
Kostyniuk CL et al. The ubiquitous and tissue specific promoters of the human SRC gene are repressed by inhibitors of histone deacetylases. 2002 Oncogene pmid:12214274
Mills JA and Kung L The effect of delayed ensiling and application of a propionic acid-based additive on the fermentation of barley silage. 2002 J. Dairy Sci. pmid:12214989
Kang HY et al. Differential modulation of androgen receptor-mediated transactivation by Smad3 and tumor suppressor Smad4. 2002 J. Biol. Chem. pmid:12226080
Lynch CA et al. Reactivation of a silenced H19 gene in human rhabdomyosarcoma by demethylation of DNA but not by histone hyperacetylation. 2002 Mol. Cancer pmid:12234381
Jesse TW et al. Production of butanol from starch-based waste packing peanuts and agricultural waste. 2002 J. Ind. Microbiol. Biotechnol. pmid:12242632
Harithsa S et al. Mercury and lead tolerance in hypersaline sulfate-reducing bacteria. 2002 Mar. Pollut. Bull. pmid:12269474
Suzuki-Mizushima Y et al. Enhancement of NGF- and cholera toxin-induced neurite outgrowth by butyrate in PC12 cells. 2002 Brain Res. pmid:12270499
Kenefick DG et al. Plant water uptake by hard red winter wheat (Triticum aestivum L.) genotypes at 2 degrees C and low light intensity. 2002 BMC Plant Biol. pmid:12350232
Kien CL et al. Quantitation of colonic luminal synthesis of butyric acid in piglets. 2002 J. Pediatr. Gastroenterol. Nutr. pmid:12352521
Albers C et al. Synthesis of a psilocin hapten and a protein-hapten conjugate. 2002 J. Pharm. Pharmacol. pmid:12356281
Kabel MA et al. In vitro fermentability of differently substituted xylo-oligosaccharides. 2002 J. Agric. Food Chem. pmid:12358503
Hernández-Eugenio G et al. Clostridium thiosulfatireducens sp. nov., a proteolytic, thiosulfate- and sulfur-reducing bacterium isolated from an upflow anaerobic sludge blanket (UASB) reactor. 2002 Int. J. Syst. Evol. Microbiol. pmid:12361247
Downes J et al. Shuttleworthia satelles gen. nov., sp. nov., isolated from the human oral cavity. 2002 Int. J. Syst. Evol. Microbiol. pmid:12361248
Alain K et al. Caminicella sporogenes gen. nov., sp. nov., a novel thermophilic spore-forming bacterium isolated from an East-Pacific Rise hydrothermal vent. 2002 Int. J. Syst. Evol. Microbiol. pmid:12361265
Elder JT and Zhao X Evidence for local control of gene expression in the epidermal differentiation complex. 2002 Exp. Dermatol. pmid:12366693
Levantesi C et al. Analysis of the microbial community structure and function of a laboratory scale enhanced biological phosphorus removal reactor. 2002 Environ. Microbiol. pmid:12366750
Kim EJ et al. Determination of a new reversible proton pump inhibitor, DBM-819, in human plasma and urine, and rat tissue homogenates by high-performance liquid chromatography. 2002 J Pharm Biomed Anal pmid:12367675
Tóth M et al. Identification of sex pheromone composition of click beetle Agriotes brevis candeze. 2002 J. Chem. Ecol. pmid:12371816
Coats SR et al. Ligand-specific control of src-suppressed C kinase substrate gene expression. 2002 Biochem. Biophys. Res. Commun. pmid:12372401
Cooper GJ and Fong P Relationship between intracellular pH and chloride in Xenopus oocytes expressing the chloride channel ClC-0. 2003 Am. J. Physiol., Cell Physiol. pmid:12388074
Millard AL et al. Butyrate affects differentiation, maturation and function of human monocyte-derived dendritic cells and macrophages. 2002 Clin. Exp. Immunol. pmid:12390312
Usenko TN et al. [Transformation with the E1A + cHa-ras oncogenes enhances the trans-repressor function of the Elk-1 transcription factor]. Mol. Biol. (Mosk.) pmid:12391846
Witt O et al. Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. 2003 Blood pmid:12393499
Pace BS et al. Short-chain fatty acid derivatives induce fetal globin expression and erythropoiesis in vivo. 2002 Blood pmid:12393583
Lin J et al. Variable effects of short chain fatty acids and lactic acid in inducing intestinal mucosal injury in newborn rats. 2002 J. Pediatr. Gastroenterol. Nutr. pmid:12394382
Chen Z et al. Induction and superinduction of growth arrest and DNA damage gene 45 (GADD45) alpha and beta messenger RNAs by histone deacetylase inhibitors trichostatin A (TSA) and butyrate in SW620 human colon carcinoma cells. 2002 Cancer Lett. pmid:12406558
Gálfi P et al. Apoptosis sensitivity is not correlated with sensitivity to proliferation inhibition by the histone deacetylase inhibitors butyrate and TSA. 2002 Cancer Lett. pmid:12406559
Bornet FR et al. Nutritional aspects of short-chain fructooligosaccharides: natural occurrence, chemistry, physiology and health implications. 2002 Dig Liver Dis pmid:12408453
Medina B et al. Effect of a preparation of Saccharomyces cerevisiae on microbial profiles and fermentation patterns in the large intestine of horses fed a high fiber or a high starch diet. 2002 J. Anim. Sci. pmid:12413082
Travers H et al. Human CD34+ hematopoietic progenitor cells hyperacetylate core histones in response to sodium butyrate, but not trichostatin A. 2002 Exp. Cell Res. pmid:12413881
Wilson AJ et al. Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention. 2002 Cancer Res. pmid:12414619
Lynch HA and Martin SA Effects of Saccharomyces cerevisiae culture and Saccharomyces cerevisiae live cells on in vitro mixed ruminal microorganism fermentation. 2002 J. Dairy Sci. pmid:12416814
Shen Z et al. [The promoter effects of sodium butyrate on the malignant transformation of the immortalized esophageal epithelium induced by human papillomavirus]. 2002 Zhonghua Bing Li Xue Za Zhi pmid:12417090
Ith M et al. Observation and identification of metabolites emerging during postmortem decomposition of brain tissue by means of in situ 1H-magnetic resonance spectroscopy. 2002 Magn Reson Med pmid:12418008
Gomez-Vargas P and Vig BK Differential induction of numerical chromosome changes by sodium butyrate in two transformed cell lines. 2002 Cancer Genet. Cytogenet. pmid:12419586
Hong MY et al. Fish oil increases mitochondrial phospholipid unsaturation, upregulating reactive oxygen species and apoptosis in rat colonocytes. 2002 Carcinogenesis pmid:12419841
Rodríguez-Cabezas ME et al. Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. 2002 J. Nutr. pmid:12421838
Cao Z et al. [Induction of human cervical carcinoma by human papilloma virus and tumor promoters]. 2002 Zhonghua Yi Xue Za Zhi pmid:12425820
Chethankumar M et al. Butyric acid modulates activities of intestinal and renal disaccharidases in experimentally induced diabetic rats. 2002 Nahrung pmid:12428451
Kucerová D et al. Response of HT29 cells to butyrate depends on time of exposure and glucose deprivation. 2002 Int. J. Mol. Med. pmid:12430007
Hebb AL et al. Odor-induced variation in anxiety-like behavior in mice is associated with discrete and differential effects on mesocorticolimbic cholecystokinin mRNA expression. 2002 Neuropsychopharmacology pmid:12431849
Omotehara F et al. Vesnarinone, a differentiation inducing drug, directly activates p21(waf1) gene promoter via Sp1 sites in a human salivary gland cancer cell line. 2002 Br. J. Cancer pmid:12434298
Tarrerias AL et al. Short-chain fatty acid enemas fail to decrease colonic hypersensitivity and inflammation in TNBS-induced colonic inflammation in rats. 2002 Pain pmid:12435462
Barshishat M et al. Butyrate down-regulates CD44 transcription and liver colonisation in a highly metastatic human colon carcinoma cell line. 2002 Br. J. Cancer pmid:12439723
Moretti A et al. Cell division cycle control in embryonal and alveolar rhabdomyosarcomas. 2002 Eur. J. Cancer pmid:12441266
Shao RH et al. Arginine butyrate increases the cytotoxicity of DAB(389)IL-2 in leukemia and lymphoma cells by upregulation of IL-2Rbeta gene. 2002 Leuk. Res. pmid:12443879
Yu S and Semprini L Comparison of trichloroethylene reductive dehalogenation by microbial communities stimulated on silicon-based organic compounds as slow-release anaerobic substrates. 2002 Water Res. pmid:12448546
Lawhon SD et al. Intestinal short-chain fatty acids alter Salmonella typhimurium invasion gene expression and virulence through BarA/SirA. 2002 Mol. Microbiol. pmid:12453229
Mukhtar N et al. Sphingolipids from Conyza canadensis. 2002 Phytochemistry pmid:12453535