ERIODICTYOL

Eriodictyol is a lipid of Polyketides (PK) class. Eriodictyol is associated with abnormalities such as Hyperostosis, Diffuse Idiopathic Skeletal, Macular degeneration, Consumption-archaic term for TB, Retinal Diseases and PARAGANGLIOMAS 4. The involved functions are known as glutathione biosynthetic process, Cytoprotection, Oxidants, protein expression and Cell Survival. Eriodictyol often locates in Cytoplasmic matrix, Protoplasm, Cytoplasmic, Cell Fraction and Back. The associated genes with Eriodictyol are NQO, HMOX1 gene, IMPACT gene, RPS6KA3 gene and GDNF gene.

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Introduction

To understand associated biological information of ERIODICTYOL, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with ERIODICTYOL?

ERIODICTYOL is suspected in Macular degeneration, Retinal Diseases, PARAGANGLIOMAS 4 and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with ERIODICTYOL

MeSH term MeSH ID Detail
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Dermatitis, Atopic D003876 19 associated lipids
Total 3

PubChem Associated disorders and diseases

What pathways are associated with ERIODICTYOL

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with ERIODICTYOL?

Related references are published most in these journals:

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What functions are associated with ERIODICTYOL?


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Function Cross reference Weighted score Related literatures

What lipids are associated with ERIODICTYOL?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with ERIODICTYOL?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with ERIODICTYOL?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with ERIODICTYOL

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Authors Title Published Journal PubMed Link
Wang Y et al. Eriodictyol inhibits IL-1β-induced inflammatory response in human osteoarthritis chondrocytes. 2018 Biomed. Pharmacother. pmid:30257325
He P et al. Eriodictyol Attenuates LPS-Induced Neuroinflammation, Amyloidogenesis, and Cognitive Impairments via the Inhibition of NF-κB in Male C57BL/6J Mice and BV2 Microglial Cells. 2018 J. Agric. Food Chem. pmid:30208700
Khlifi R et al. Heat treatment improves the immunomodulatory and cellular antioxidant behavior of a natural flavanone: Eriodictyol. 2018 Int. Immunopharmacol. pmid:29913426
Rajan VK et al. Studies on the UV filtering and radical scavenging capacity of the bitter masking flavanone Eriodictyol. 2018 J. Photochem. Photobiol. B, Biol. pmid:29981487
Xuewen H et al. Eriodictyol protects against Staphylococcus aureus-induced lung cell injury by inhibiting alpha-hemolysin expression. 2018 World J. Microbiol. Biotechnol. pmid:29671126
Hameed A et al. Eriodictyol stimulates insulin secretion through cAMP/PKA signaling pathway in mice islets. 2018 Eur. J. Pharmacol. pmid:29229531
Armah FA et al. Leishmanicidal activity of the root bark of Erythrophleum Ivorense (Fabaceae) and identification of some of its compounds by ultra-performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-QTOF-MS/MS). 2018 J Ethnopharmacol pmid:28970156
Liszt KI et al. Characterization of Bitter Compounds via Modulation of Proton Secretion in Human Gastric Parietal Cells in Culture. 2018 J. Agric. Food Chem. pmid:28525714
Barreca D et al. Flavanones: Citrus phytochemical with health-promoting properties. 2017 Biofactors pmid:28497905
Wang Z et al. Eriodictyol, Not Its Glucuronide Metabolites, Attenuates Acetaminophen-Induced Hepatotoxicity. 2017 Mol. Pharm. pmid:28654297
Liang Y et al. Eriodictyol 7‑O‑β‑D glucopyranoside from Coreopsis tinctoria Nutt. ameliorates lipid disorders via protecting mitochondrial function and suppressing lipogenesis. 2017 Mol Med Rep pmid:28627652
Lee D et al. Biotechnological Production of Dimethoxyflavonoids Using a Fusion Flavonoid O-Methyltransferase Possessing Both 3'- and 7-O-Methyltransferase Activities. 2017 J. Nat. Prod. pmid:28429944
Chobot V et al. Pro- and Antioxidant Activity of Three Selected Flavan Type Flavonoids: Catechin, Eriodictyol and Taxifolin. 2016 Int J Mol Sci pmid:27898046
Yamashita M et al. The Combination of Green Tea Extract and Eriodictyol Inhibited High-Fat/High-Sucrose Diet-Induced Cholesterol Upregulation Is Accompanied by Suppression of Cholesterol Synthesis Enzymes. 2016 J. Nutr. Sci. Vitaminol. pmid:27725410
Mokdad-Bzeouich I et al. Investigation of immunomodulatory and anti-inflammatory effects of eriodictyol through its cellular anti-oxidant activity. 2016 Cell Stress Chaperones pmid:27250501
Ferreira PS et al. Citrus flavanones prevent systemic inflammation and ameliorate oxidative stress in C57BL/6J mice fed high-fat diet. 2016 Food Funct pmid:27182608
Wang W et al. Protective Effects of Chinese Herbal Medicine Rhizoma drynariae in Rats After Traumatic Brain Injury and Identification of Active Compound. 2016 Mol. Neurobiol. pmid:26334614
Tisserant LP et al. C NMR and LC-MS Profiling of Stilbenes from Elicited Grapevine Hairy Root Cultures. 2016 J. Nat. Prod. pmid:27933900
Chu LL et al. Hydroxylation of diverse flavonoids by CYP450 BM3 variants: biosynthesis of eriodictyol from naringenin in whole cells and its biological activities. 2016 Microb. Cell Fact. pmid:27495155
Ferreira Ede O et al. Neuroinflammatory response to experimental stroke is inhibited by eriodictyol. 2016 Behav. Brain Res. pmid:27353856
Song F et al. Eriodictyol Inhibits RANKL-Induced Osteoclast Formation and Function Via Inhibition of NFATc1 Activity. 2016 J. Cell. Physiol. pmid:26754483
Li CZ et al. Eriodictyol attenuates cisplatin-induced kidney injury by inhibiting oxidative stress and inflammation. 2016 Eur. J. Pharmacol. pmid:26723515
Lee SE et al. Eriodictyol Protects Endothelial Cells against Oxidative Stress-Induced Cell Death through Modulating ERK/Nrf2/ARE-Dependent Heme Oxygenase-1 Expression. 2015 Int J Mol Sci pmid:26132561
Costa G et al. Flavan hetero-dimers in the Cymbopogon citratus infusion tannin fraction and their contribution to the antioxidant activity. 2015 Food Funct pmid:25652784
Yang L et al. Enhanced action of apigenin and naringenin combination on estrogen receptor activation in non-malignant colonocytes: implications on sorghum-derived phytoestrogens. 2015 Food Funct pmid:25553799
Hanáková Z et al. C-Geranylated Flavanones from Paulownia tomentosa Fruits as Potential Anti-inflammatory Compounds Acting via Inhibition of TNF-α Production. 2015 J. Nat. Prod. pmid:25735399
Lee J et al. Eriodicyol inhibits osteoclast differentiation and ovariectomy-induced bone loss in vivo. 2015 Exp. Cell Res. pmid:26450448
Imen MB et al. Anti-melanogenesis and antigenotoxic activities of eriodictyol in murine melanoma (B16-F10) and primary human keratinocyte cells. 2015 Life Sci. pmid:26141996
Jing X et al. Eriodictyol Attenuates β-Amyloid 25-35 Peptide-Induced Oxidative Cell Death in Primary Cultured Neurons by Activation of Nrf2. 2015 Neurochem. Res. pmid:25994859
Stark TD et al. Antioxidative compounds from Garcinia buchananii stem bark. 2015 J. Nat. Prod. pmid:25625705
Li H et al. R-eriodictyol and S-eriodictyol exhibited comparable effect against H2O2-induced oxidative stress in EA.hy926 cells. 2014 Drug Discov Ther pmid:25382557
Zhu S et al. Efficient synthesis of eriodictyol from L-tyrosine in Escherichia coli. 2014 Appl. Environ. Microbiol. pmid:24610848
Foresti R et al. Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. 2013 Pharmacol. Res. pmid:23942037
Lee E et al. Binding model for eriodictyol to Jun-N terminal kinase and its anti-inflammatory signaling pathway. 2013 BMB Rep pmid:24195792
Park SJ et al. Effect of eriodictyol on the development of atopic dermatitis-like lesions in ICR mice. 2013 Biol. Pharm. Bull. pmid:23902981
Liu Q et al. Biosynthesis of homoeriodictyol from eriodictyol by flavone 3'-O-methyltransferase from recombinant Yarrowia lioplytica: Heterologous expression, biochemical characterization, and optimal transformation. 2013 J. Biotechnol. pmid:23906843
Jing X et al. Eriodictyol-7-O-glucoside activates Nrf2 and protects against cerebral ischemic injury. 2013 Toxicol. Appl. Pharmacol. pmid:24466583
Straub I et al. Citrus fruit and fabacea secondary metabolites potently and selectively block TRPM3. 2013 Br. J. Pharmacol. pmid:23190005
Huang FC et al. Differential expression and functional characterization of the NADPH cytochrome P450 reductase genes from Nothapodytes foetida. 2012 Plant Sci. pmid:22608516
Kobayashi S et al. Transport mechanisms of flavanone aglycones across Caco-2 cell monolayers and artificial PAMPA membranes. 2012 J. Pharm. Pharmacol. pmid:22150672
Guo X et al. Separation of the enantiomers of naringenin and eriodictyol by amylose-based chiral reversed-phase high-performance liquid chromatography. 2012 Drug Discov Ther pmid:23337820
Huvaere K et al. Flavonoid deactivation of excited state flavins: reaction monitoring by mass spectrometry. 2012 J. Agric. Food Chem. pmid:22889117
Kizaibek M et al. Towards modernization of the formulation of the traditional uighur medicine herbal preparation abnormal savda munziq. 2012 Evid Based Complement Alternat Med pmid:21837249
Gohari AR et al. Evaluation of the cytotoxicity of Satureja spicigera and its main compounds. 2012 ScientificWorldJournal pmid:22623883
Chen H et al. Prediction of molecular targets of cancer preventing flavonoid compounds using computational methods. 2012 PLoS ONE pmid:22693608
Devi PS et al. DNA Damage Protecting Activity and Free Radical Scavenging Activity of Anthocyanins from Red Sorghum (Sorghum bicolor) Bran. 2012 Biotechnol Res Int pmid:22400119
Qiu J et al. Screening natural antioxidants in peanut shell using DPPH-HPLC-DAD-TOF/MS methods. 2012 Food Chem pmid:22980814
Huang Z et al. A new isoflavone from the mangrove endophytic fungus Fusarium sp. (ZZF60). 2012 Nat. Prod. Res. pmid:21714733
Park S et al. Topical Application of Chrysanthemum indicum L. Attenuates the Development of Atopic Dermatitis-Like Skin Lesions by Suppressing Serum IgE Levels, IFN-γ, and IL-4 in Nc/Nga Mice. 2012 Evid Based Complement Alternat Med pmid:22454686
Lou H et al. Eriodictyol protects against H(2)O(2)-induced neuron-like PC12 cell death through activation of Nrf2/ARE signaling pathway. 2012 Neurochem. Int. pmid:22609376
Zhang WY et al. Effect of eriodictyol on glucose uptake and insulin resistance in vitro. 2012 J. Agric. Food Chem. pmid:22809065
Yoo JM et al. Inhibitory effect of eriodictyol on IgE/Ag-induced type I hypersensitivity. 2012 Biosci. Biotechnol. Biochem. pmid:22785465
Hu YF and Wu CC [Chemical constituents from stems of Lonicera macranthoides]. 2012 Zhong Yao Cai pmid:22734414
Bucolo C et al. Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats. 2012 Biochem. Pharmacol. pmid:22484312
Monforte MT et al. Protective effect of Calamintha officinalis Moench leaves against alcohol-induced gastric mucosa injury in rats. Macroscopic, histologic and phytochemical analysis. 2012 Phytother Res pmid:22076933
Hu Q et al. Eriodictyol-7-O-glucoside, a novel Nrf2 activator, confers protection against cisplatin-induced toxicity. 2012 Food Chem. Toxicol. pmid:22465804
Habtemariam S The anti-obesity potential of sigmoidin A. 2012 Pharm Biol pmid:22978690
Umar KM et al. Engineering the production of major catechins by Escherichia coli carrying metabolite genes of Camellia sinensis. 2012 ScientificWorldJournal pmid:22645428
Cho N et al. Neuroprotective and anti-inflammatory effects of flavonoids isolated from Rhus verniciflua in neuronal HT22 and microglial BV2 cell lines. 2012 Food Chem. Toxicol. pmid:22465834
Cho JK et al. Cholinestrase inhibitory effects of geranylated flavonoids from Paulownia tomentosa fruits. 2012 Bioorg. Med. Chem. pmid:22445674
Lavola A et al. Bioactive polyphenols in leaves, stems, and berries of Saskatoon (Amelanchier alnifolia Nutt.) cultivars. 2012 J. Agric. Food Chem. pmid:22220589
López-Camarillo C et al. Protein kinases and transcription factors activation in response to UV-radiation of skin: implications for carcinogenesis. 2012 Int J Mol Sci pmid:22312244
Freischmidt A et al. Contribution of flavonoids and catechol to the reduction of ICAM-1 expression in endothelial cells by a standardised Willow bark extract. 2012 Phytomedicine pmid:21982436
Sung PH et al. Functional expression of geraniol 10-hydroxylase reveals its dual function in the biosynthesis of terpenoid and phenylpropanoid. 2011 J. Agric. Food Chem. pmid:21504162
Vandeputte OM et al. The flavanone naringenin reduces the production of quorum sensing-controlled virulence factors in Pseudomonas aeruginosa PAO1. 2011 Microbiology (Reading, Engl.) pmid:21546585
Kwon C and Jung S Stereoisomeric separation of some flavanones using highly succinate-substituted α-cyclosophoro-octadecaoses as chiral additives in capillary electrophoresis. 2011 Carbohydr. Res. pmid:21093852
Stefek M Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. 2011 Interdiscip Toxicol pmid:21753902
Shulman M et al. Enhancement of naringenin bioavailability by complexation with hydroxypropyl-β-cyclodextrin. [corrected]. 2011 PLoS ONE pmid:21494673
Gillman JD et al. Loss-of-function mutations affecting a specific Glycine max R2R3 MYB transcription factor result in brown hilum and brown seed coats. 2011 BMC Plant Biol. pmid:22070454
Sumbul S et al. Role of phenolic compounds in peptic ulcer: An overview. 2011 J Pharm Bioallied Sci pmid:21966156
Kalra P et al. Antiulcer effect of the methanolic extract of Tamarindus indica seeds in different experimental models. 2011 J Pharm Bioallied Sci pmid:21687352
Venkateswara Rao G et al. Chemical constituents and biological studies of Origanum vulgare Linn. 2011 Pharmacognosy Res pmid:21772760
Liu K et al. Eriodictyol inhibits RSK2-ATF1 signaling and suppresses EGF-induced neoplastic cell transformation. 2011 J. Biol. Chem. pmid:21098035
Rossato MF et al. Eriodictyol: a flavonoid antagonist of the TRPV1 receptor with antioxidant activity. 2011 Biochem. Pharmacol. pmid:21087598
Lee ER et al. Cytoprotective effect of eriodictyol in UV-irradiated keratinocytes via phosphatase-dependent modulation of both the p38 MAPK and Akt signaling pathways. 2011 Cell. Physiol. Biochem. pmid:21691069
Lee JK Anti-inflammatory effects of eriodictyol in lipopolysaccharide-stimulated raw 264.7 murine macrophages. 2011 Arch. Pharm. Res. pmid:21544733
Shi CY et al. Deep sequencing of the Camellia sinensis transcriptome revealed candidate genes for major metabolic pathways of tea-specific compounds. 2011 BMC Genomics pmid:21356090
Sharma M et al. Identification of the pr1 gene product completes the anthocyanin biosynthesis pathway of maize. 2011 Genetics pmid:21385724
Herath W and Khan IA Microbial metabolism. Part 13. Metabolites of hesperetin. 2011 Bioorg. Med. Chem. Lett. pmid:21873058
Jeong E and Lee JY Intrinsic and extrinsic regulation of innate immune receptors. 2011 Yonsei Med. J. pmid:21488180
Bhadoriya SS et al. Tamarindus indica: Extent of explored potential. 2011 Pharmacogn Rev pmid:22096321
Soehnlen MK et al. Identification of novel small molecule antimicrobials targeting Mycoplasma bovis. 2011 J. Antimicrob. Chemother. pmid:21393230
Dong X et al. Protective effect of canolol from oxidative stress-induced cell damage in ARPE-19 cells via an ERK mediated antioxidative pathway. 2011 Mol. Vis. pmid:21850179
Mirza S et al. Expression and distribution of the class III ubiquitin-conjugating enzymes in the retina. 2010 Mol. Vis. pmid:21139979
Jin MJ et al. Effects of gut microflora on pharmacokinetics of hesperidin: a study on non-antibiotic and pseudo-germ-free rats. 2010 J. Toxicol. Environ. Health Part A pmid:20954071
Jeon Y et al. Carboxymethylated cyclosophoraose as a novel chiral additive for the stereoisomeric separation of some flavonoids by capillary electrophoresis. 2010 Carbohydr. Res. pmid:20850110
Krogholm KS et al. Free fruit at workplace intervention increases total fruit intake: a validation study using 24 h dietary recall and urinary flavonoid excretion. 2010 Eur J Clin Nutr pmid:20683461
Bonaterra GA et al. In vitro anti-proliferative effects of the willow bark extract STW 33-I. 2010 Arzneimittelforschung pmid:20648923
Sanz M et al. Phenolic compounds in cherry ( Prunus avium ) heartwood with a view to their use in cooperage. 2010 J. Agric. Food Chem. pmid:20302370
Chatzopoulou A et al. Depsides and other polar constituents from Origanum dictamnus L. and their in vitro antimicrobial activity in clinical strains. 2010 J. Agric. Food Chem. pmid:20423097
Antal DS et al. Cotinus coggygria wood: novel flavanone dimer and development of an HPLC/UV/MS method for the simultaneous determination of fourteen phenolic constituents. 2010 Planta Med. pmid:20446241
Nakashima S et al. Melanogenesis inhibitors from the desert plant Anastatica hierochuntica in B16 melanoma cells. 2010 Bioorg. Med. Chem. pmid:20189399
Meng X et al. Effects of Various Flavonoids on the α-Synuclein Fibrillation Process. 2010 Parkinsons Dis pmid:20976092
Tomaino A et al. Antioxidant activity and phenolic profile of pistachio (Pistacia vera L., variety Bronte) seeds and skins. 2010 Biochimie pmid:20388531
Habtemariam S and Dagne E Comparative antioxidant, prooxidant and cytotoxic activity of sigmoidin A and eriodictyol. 2010 Planta Med. pmid:19941260
Treutter D Managing phenol contents in crop plants by phytochemical farming and breeding-visions and constraints. 2010 Int J Mol Sci pmid:20479987
Suttana W et al. Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols. 2010 Mol. Cancer pmid:20438634
Boros B et al. Determination of polyphenolic compounds by liquid chromatography-mass spectrometry in Thymus species. 2010 J Chromatogr A pmid:20692666
Du Y et al. CYP93G2 is a flavanone 2-hydroxylase required for C-glycosylflavone biosynthesis in rice. 2010 Plant Physiol. pmid:20647377
Fliegmann J et al. Flavone synthase II (CYP93B16) from soybean (Glycine max L.). 2010 Phytochemistry pmid:20132953