Hesperetin is a lipid of Polyketides (PK) class. Hesperetin is associated with abnormalities such as Corn of toe, Ischemia, Osteoporosis, Consumption-archaic term for TB and Wiskott-Aldrich Syndrome. The involved functions are known as conjugation, inhibitors, Process, mRNA Expression and Adjudication. Hesperetin often locates in Entire intestinal epithelium, Protoplasm, Membrane, Shoulder and Back. The associated genes with Hesperetin are ABCG2 gene, ABCC2 gene, FATE1 gene, ABCB1 gene and P-glycoprotein 2.
To understand associated biological information of hesperetin, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
hesperetin is suspected in Corn of toe, Ischemia, Osteoporosis, Diabetes and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with hesperetin
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Lee S et al. | In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones. | 2018 | Molecules | pmid:29932100 |
DuranoÄŸlu D et al. | Synthesis of hesperetin-loaded PLGA nanoparticles by two different experimental design methods and biological evaluation of optimized nanoparticles. | 2018 | Nanotechnology | pmid:29972381 |
Khalaj R et al. | Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism. | 2018 | Int. J. Dev. Neurosci. | pmid:29966739 |
Baradaran S et al. | Hesperetin reduces myelin damage and ameliorates glial activation in lysolecithin-induced focal demyelination model of rat optic chiasm. | 2018 | Life Sci. | pmid:30056861 |
Huang AL et al. | Design, synthesis and investigation of potential anti-inflammatory activity of O-alkyl and O-benzyl hesperetin derivatives. | 2018 | Int. Immunopharmacol. | pmid:29852476 |
Ma Y et al. | Metabolism of Phenolic Compounds in LPS-stimulated Raw264.7 Cells Can Impact Their Anti-inflammatory efficacy: Indication of Hesperetin. | 2018 | J. Agric. Food Chem. | pmid:29792322 |
Nakazawa Y et al. | Effect of hesperetin derivatives on the development of selenite‑induced cataracts in rats. | 2018 | Mol Med Rep | pmid:29845214 |
Pelikh O et al. | Nanocrystals for improved dermal drug delivery. | 2018 | Eur J Pharm Biopharm | pmid:29680482 |
Vander Dos Santos R et al. | Citrus bioflavonoid, hesperetin, as inhibitor of two thrombin-like snake venom serine proteases isolated from Crotalus simus. | 2018 | Toxicon | pmid:29337219 |
Elango R et al. | Hesperetin induces an apoptosis-triggered extrinsic pathway and a p53- independent pathway in human lung cancer H522 cells. | 2018 | J Asian Nat Prod Res | pmid:28537448 |