Lee S et al. |
In Silico Docking and In Vitro Approaches towards BACE1 and Cholinesterases Inhibitory Effect of Citrus Flavanones. |
2018 |
Molecules |
pmid:29932100
|
Pereira-Caro G et al. |
Catabolism of citrus flavanones by the probiotics Bifidobacterium longum and Lactobacillus rhamnosus. |
2018 |
Eur J Nutr |
pmid:27722779
|
González-Alfonso JL et al. |
Optimization of Regioselective α-Glucosylation of Hesperetin Catalyzed by Cyclodextrin Glucanotransferase. |
2018 |
Molecules |
pmid:30400664
|
Sak K et al. |
Suppression of Taxanes Cytotoxicity by Citrus Flavonoid Hesperetin in PPC-1 Human Prostate Cancer Cells. |
2018 |
Anticancer Res. |
pmid:30396939
|
Park JH et al. |
Hesperetin mitigates acrolein-induced apoptosis in lung cells in vitro and in vivo. |
2018 |
Redox Rep. |
pmid:30325253
|
Samie A et al. |
Hesperetin, a citrus flavonoid, attenuates testicular damage in diabetic rats via inhibition of oxidative stress, inflammation, and apoptosis. |
2018 |
Life Sci. |
pmid:30179627
|
DuranoÄŸlu D et al. |
Synthesis of hesperetin-loaded PLGA nanoparticles by two different experimental design methods and biological evaluation of optimized nanoparticles. |
2018 |
Nanotechnology |
pmid:29972381
|
Khalaj R et al. |
Hesperetin and it nanocrystals ameliorate social behavior deficits and oxido-inflammatory stress in rat model of autism. |
2018 |
Int. J. Dev. Neurosci. |
pmid:29966739
|
Baradaran S et al. |
Hesperetin reduces myelin damage and ameliorates glial activation in lysolecithin-induced focal demyelination model of rat optic chiasm. |
2018 |
Life Sci. |
pmid:30056861
|
Huang AL et al. |
Design, synthesis and investigation of potential anti-inflammatory activity of O-alkyl and O-benzyl hesperetin derivatives. |
2018 |
Int. Immunopharmacol. |
pmid:29852476
|
Ma Y et al. |
Metabolism of Phenolic Compounds in LPS-stimulated Raw264.7 Cells Can Impact Their Anti-inflammatory efficacy: Indication of Hesperetin. |
2018 |
J. Agric. Food Chem. |
pmid:29792322
|
Nakazawa Y et al. |
Effect of hesperetin derivatives on the development of selenite‑induced cataracts in rats. |
2018 |
Mol Med Rep |
pmid:29845214
|
Tan YQ et al. |
The citrus flavonone hesperetin attenuates the nuclear translocation of aryl hydrocarbon receptor. |
2018 |
Comp. Biochem. Physiol. C Toxicol. Pharmacol. |
pmid:29763690
|
Pelikh O et al. |
Nanocrystals for improved dermal drug delivery. |
2018 |
Eur J Pharm Biopharm |
pmid:29680482
|
Wang DD et al. |
Magnetic molecularly imprinted polymer for the selective extraction of hesperetin from the dried pericarp of Citrus reticulata Blanco. |
2018 |
Talanta |
pmid:29674047
|
Vander Dos Santos R et al. |
Citrus bioflavonoid, hesperetin, as inhibitor of two thrombin-like snake venom serine proteases isolated from Crotalus simus. |
2018 |
Toxicon |
pmid:29337219
|
Kheradmand E et al. |
Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer's disease. |
2018 |
Biomed. Pharmacother. |
pmid:29136946
|
Elango R et al. |
Hesperetin induces an apoptosis-triggered extrinsic pathway and a p53- independent pathway in human lung cancer H522 cells. |
2018 |
J Asian Nat Prod Res |
pmid:28537448
|
Meng C et al. |
Preventive effect of hesperidin modulates inflammatory responses and antioxidant status following acute myocardial infarction through the expression of PPAR‑γ and Bcl‑2 in model mice. |
2018 |
Mol Med Rep |
pmid:29115547
|
Mary Lazer L et al. |
Chitosan-based nano-formulation enhances the anticancer efficacy of hesperetin. |
2018 |
Int. J. Biol. Macromol. |
pmid:29032208
|
Loizzo MR et al. |
Ruta chalepensis L. (Rutaceae) leaf extract: chemical composition, antioxidant and hypoglicaemic activities. |
2018 |
Nat. Prod. Res. |
pmid:28486828
|
Liu T et al. |
Production of drug nanosuspensions: effect of drug physical properties on nanosizing efficiency. |
2018 |
Drug Dev Ind Pharm |
pmid:28956456
|
Li Y et al. |
Drug interaction study of flavonoids toward CYP3A4 and their quantitative structure activity relationship (QSAR) analysis for predicting potential effects. |
2018 |
Toxicol. Lett. |
pmid:29753067
|
do Nascimento GS et al. |
The acute effects of citrus flavanones on the metabolism of glycogen and monosaccharides in the isolated perfused rat liver. |
2018 |
Toxicol. Lett. |
pmid:29626522
|
Ding HW et al. |
Design, synthesis and biological evaluation of hesperetin derivatives as potent anti-inflammatory agent. |
2017 |
Fitoterapia |
pmid:28774689
|
Babukumar S et al. |
Molecular effects of hesperetin, a citrus flavanone on7,12-dimethylbenz(a)anthracene induced buccal pouch squamous cell carcinoma in golden Syrian hamsters. |
2017 |
Arch. Physiol. Biochem. |
pmid:28457144
|
Zareei S et al. |
Inhibition of liver alanine aminotransferase and aspartate aminotransferase by hesperidin and its aglycone hesperetin: An in vitro and in silico study. |
2017 |
Life Sci. |
pmid:28385612
|
Noshita T et al. |
Structure-activity relationship of flavanone. Anti-degranulation activity of 7-O-substituted hesperetin. |
2017 |
Nat. Prod. Res. |
pmid:28105859
|
Zhu C et al. |
Hesperetin protects against HO-triggered oxidative damage via upregulation of the Keap1-Nrf2/HO-1 signal pathway in ARPE-19 cells. |
2017 |
Biomed. Pharmacother. |
pmid:28103505
|
Coutinho L et al. |
Hesperetin-etoposide combinations induce cytotoxicity in U2OS cells: Implications on therapeutic developments for osteosarcoma. |
2017 |
DNA Repair (Amst.) |
pmid:28063664
|
Arya A et al. |
Bioflavonoid hesperetin overcome bicalutamide induced toxicity by co-delivery in novel SNEDDS formulations: Optimization, in vivo evaluation and uptake mechanism. |
2017 |
Mater Sci Eng C Mater Biol Appl |
pmid:27987794
|
Jung KY et al. |
Synthesis and biological evaluation of hesperetin derivatives as agents inducing apoptosis. |
2017 |
Bioorg. Med. Chem. |
pmid:27840137
|
Li C and Schluesener H |
Health-promoting effects of the citrus flavanone hesperidin. |
2017 |
Crit Rev Food Sci Nutr |
pmid:25675136
|
Bai X et al. |
The protective effect of the natural compound hesperetin against fulminant hepatitis in vivo and in vitro. |
2017 |
Br. J. Pharmacol. |
pmid:27714757
|
Chen R et al. |
Intestinal transport of HDND-7, a novel hesperetin derivative, in in vitro MDCK cell and in situ single-pass intestinal perfusion models. |
2017 |
Xenobiotica |
pmid:27535101
|
Barreca D et al. |
Flavanones: Citrus phytochemical with health-promoting properties. |
2017 |
Biofactors |
pmid:28497905
|
Xue D et al. |
The role of hesperetin on osteogenesis of human mesenchymal stem cells and its function in bone regeneration. |
2017 |
Oncotarget |
pmid:28423500
|
Menezes PD et al. |
Hesperetin-loaded lipid-core nanocapsules in polyamide: a new textile formulation for topical drug delivery. |
2017 |
Int J Nanomedicine |
pmid:28352176
|
Chadha K et al. |
Is Failure of Cocrystallization Actually a Failure? Eutectic Formation in Cocrystal Screening of Hesperetin. |
2017 |
J Pharm Sci |
pmid:28456725
|
Boonpawa R et al. |
Physiologically based kinetic modeling of hesperidin metabolism and its use to predict in vivo effective doses in humans. |
2017 |
Mol Nutr Food Res |
pmid:28218440
|
Li B et al. |
Design, Synthesis and Evaluation of Hesperetin Derivatives as Potential Multifunctional Anti-Alzheimer Agents. |
2017 |
Molecules |
pmid:28672874
|
Yang YL et al. |
Hesperetin-5,7,3'-O-triacetate suppresses airway hyperresponsiveness in ovalbumin-sensitized and challenged mice without reversing xylazine/ketamine-induced anesthesia in normal mice. |
2017 |
BMC Pharmacol Toxicol |
pmid:28558784
|
He S et al. |
Hesperetin post-treatment prevents rat cardiomyocytes from hypoxia/reoxygenation injury in vitro via activating PI3K/Akt signaling pathway. |
2017 |
Biomed. Pharmacother. |
pmid:28531921
|
Pini F et al. |
Bacterial Biosensors for in Vivo Spatiotemporal Mapping of Root Secretion. |
2017 |
Plant Physiol. |
pmid:28495892
|
Gong Y et al. |
Inhibitory effect of hesperetin on α-glucosidase: Molecular dynamics simulation integrating inhibition kinetics. |
2017 |
Int. J. Biol. Macromol. |
pmid:28322965
|
Kumar M et al. |
The renoprotective activity of hesperetin in cisplatin induced nephrotoxicity in rats: Molecular and biochemical evidence. |
2017 |
Biomed. Pharmacother. |
pmid:28320087
|
Van Rymenant E et al. |
Chronic exposure to short-chain fatty acids modulates transport and metabolism of microbiome-derived phenolics in human intestinal cells. |
2017 |
J. Nutr. Biochem. |
pmid:27840292
|
Shagirtha K et al. |
Neuroprotective efficacy of hesperetin against cadmium induced oxidative stress in the brain of rats. |
2017 |
Toxicol Ind Health |
pmid:27803291
|
Pereira-Caro G et al. |
Bioavailability of orange juice (poly)phenols: the impact of short-term cessation of training by male endurance athletes. |
2017 |
Am. J. Clin. Nutr. |
pmid:28747329
|
Zeng X et al. |
Urinary metabolite profiling of flavonoids in Chinese volunteers after consumption of orange juice by UFLC-Q-TOF-MS/MS. |
2017 |
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. |
pmid:28711784
|
Sassi A et al. |
Immunomodulatory potential of hesperetin and chrysin through the cellular and humoral response. |
2017 |
Eur. J. Pharmacol. |
pmid:28690190
|
Sammani MS et al. |
Use of multiresponse statistical techniques to optimize the separation of diosmin, hesperidin, diosmetin and hesperitin in different pharmaceutical preparations by high performance liquid chromatography with UV-DAD. |
2017 |
Talanta |
pmid:28340781
|
Lopes LAA et al. |
Inhibitory effects of flavonoids on biofilm formation by Staphylococcus aureus that overexpresses efflux protein genes. |
2017 |
Microb. Pathog. |
pmid:28365326
|
Chen X et al. |
Hesperetin derivative-14 alleviates inflammation by activating PPAR-γ in mice with CCl-induced acute liver injury and LPS-treated RAW264.7 cells. |
2017 |
Toxicol. Lett. |
pmid:28428136
|
Li WX et al. |
Hesperitin derivative-11 suppress hepatic stellate cell activation and proliferation by targeting PTEN/AKT pathway. |
2017 |
Toxicology |
pmid:27818223
|
Liu K et al. |
Chemical Evidence for Potent Xanthine Oxidase Inhibitory Activity of Ethyl Acetate Extract of Citrus aurantium L. Dried Immature Fruits. |
2016 |
Molecules |
pmid:26950105
|
Mendel M et al. |
Antispasmodic effect of selected Citrus flavonoids on rat isolated jejunum specimens. |
2016 |
Eur. J. Pharmacol. |
pmid:27720920
|
Wang H et al. |
Inhibitory effects of hesperetin on Nav1.5 channels stably expressed in HEK 293 cells and on the voltage-gated cardiac sodium current in human atrial myocytes. |
2016 |
Acta Pharmacol. Sin. |
pmid:27694909
|
Wang H et al. |
Inhibitory effects of hesperetin on Kv1.5 potassium channels stably expressed in HEK 293 cells and ultra-rapid delayed rectifier K(+) current in human atrial myocytes. |
2016 |
Eur. J. Pharmacol. |
pmid:27397430
|
Kara M et al. |
Evaluation of the protective effects of hesperetin against cisplatin-induced ototoxicity in a rat animal model. |
2016 |
Int. J. Pediatr. Otorhinolaryngol. |
pmid:27240489
|
Ren H et al. |
Hesperetin Suppresses Inflammatory Responses in Lipopolysaccharide-Induced RAW 264.7 Cells via the Inhibition of NF-κB and Activation of Nrf2/HO-1 Pathways. |
2016 |
Inflammation |
pmid:26994999
|
Asai T et al. |
Isolation and characterization of wound-induced compounds from the leaves of Citrus hassaku. |
2016 |
J. Biosci. Bioeng. |
pmid:26852089
|
Wang QQ et al. |
Hesperetin derivatives: Synthesis and anti-inflammatory activity. |
2016 |
Bioorg. Med. Chem. Lett. |
pmid:26848111
|
Bawazeer NA et al. |
Role of hesperetin in LDL-receptor expression in hepatoma HepG2 cells. |
2016 |
BMC Complement Altern Med |
pmid:27349523
|
Wu J et al. |
The novel voltammetric method for determination of hesperetin based on a sensitive electrochemical sensor. |
2016 |
Talanta |
pmid:26838382
|
Xue M et al. |
Improved Glycemic Control and Vascular Function in Overweight and Obese Subjects by Glyoxalase 1 Inducer Formulation. |
2016 |
Diabetes |
pmid:27207552
|
Costa CR et al. |
Effects of Plants on Osteogenic Differentiation and Mineralization of Periodontal Ligament Cells: A Systematic Review. |
2016 |
Phytother Res |
pmid:26822584
|
Shimouchi A et al. |
Neuroprotective effect of water-dispersible hesperetin in retinal ischemia reperfusion injury. |
2016 |
Jpn. J. Ophthalmol. |
pmid:26407617
|
Kiasalari Z et al. |
Protective Effect of Oral Hesperetin Against Unilateral Striatal 6-Hydroxydopamine Damage in the Rat. |
2016 |
Neurochem. Res. |
pmid:26700436
|
Yang LJ et al. |
Host-guest system of hesperetin and β-cyclodextrin or its derivatives: Preparation, characterization, inclusion mode, solubilization and stability. |
2016 |
Mater Sci Eng C Mater Biol Appl |
pmid:26652460
|
Wei L et al. |
Effects of hesperetin on platelet-derived growth factor-BB-induced pulmonary artery smooth muscle cell proliferation. |
2016 |
Mol Med Rep |
pmid:26647836
|
Shen C et al. |
A HPLC-MS/MS method for the quantitation of free, conjugated, and total HDND-7, a novel hesperetin derivative, in rat plasma and tissues: Application to the pharmacokinetic and tissue distribution study. |
2016 |
J Pharm Biomed Anal |
pmid:26551533
|
Wolfram J et al. |
Hesperetin Liposomes for Cancer Therapy. |
2016 |
Curr Drug Deliv |
pmid:26502889
|
Giménez-Bastida JA et al. |
Hesperetin and its sulfate and glucuronide metabolites inhibit TNF-α induced human aortic endothelial cell migration and decrease plasminogen activator inhibitor-1 (PAI-1) levels. |
2016 |
Food Funct |
pmid:26456097
|
Wu D et al. |
Hesperetin induces apoptosis of esophageal cancer cells via mitochondrial pathway mediated by the increased intracellular reactive oxygen species. |
2016 |
Tumour Biol. |
pmid:26449828
|
de Souza VT et al. |
Characterization of the antioxidant activity of aglycone and glycosylated derivatives of hesperetin: an in vitro and in vivo study. |
2016 |
J. Mol. Recognit. |
pmid:26370929
|
Erenler R et al. |
Isolation and identification of chemical constituents from Origanum majorana and investigation of antiproliferative and antioxidant activities. |
2016 |
J. Sci. Food Agric. |
pmid:25721137
|
Baranowska I et al. |
Development and validation of a RP-UHPLC-ESI-MS/MS method for the chiral separation and determination of flavanone, naringenin and hesperetin enantiomers. |
2016 |
Talanta |
pmid:27474296
|
Kim SY et al. |
Enhanced anti-oxidative effect of fermented Korean mistletoe is originated from an increase in the contents of caffeic acid and lyoniresinol. |
2016 |
Food Funct |
pmid:27072079
|
Shen C et al. |
Single Dose Oral and Intravenous Pharmacokinetics and Tissue Distribution of a Novel Hesperetin Derivative MTBH in Rats. |
2016 |
Eur J Drug Metab Pharmacokinet |
pmid:26254910
|
Miler M et al. |
Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats. |
2016 |
Exp. Gerontol. |
pmid:27587005
|
Aschoff JK et al. |
Urinary excretion of Citrus flavanones and their major catabolites after consumption of fresh oranges and pasteurized orange juice: A randomized cross-over study. |
2016 |
Mol Nutr Food Res |
pmid:27488098
|
Chandrika BB et al. |
Hesperetin and Naringenin sensitize HER2 positive cancer cells to death by serving as HER2 Tyrosine Kinase inhibitors. |
2016 |
Life Sci. |
pmid:27449398
|
Adan A and Baran Y |
Fisetin and hesperetin induced apoptosis and cell cycle arrest in chronic myeloid leukemia cells accompanied by modulation of cellular signaling. |
2016 |
Tumour Biol. |
pmid:26408178
|
Baranowska I et al. |
Simultaneous Chiral Separation of Flavanone, Naringenin, and Hesperetin Enantiomers by RP-UHPLC-DAD. |
2016 |
Chirality |
pmid:26712420
|
Tamayo LV et al. |
Copper(II) complexes with naringenin and hesperetin: cytotoxic activity against A 549 human lung adenocarcinoma cells and investigation on the mode of action. |
2016 |
Biometals |
pmid:26582127
|
Pingili R et al. |
Pharmacokinetic interaction study between flavanones (hesperetin, naringenin) and rasagiline mesylate in wistar rats. |
2016 |
Drug Dev Ind Pharm |
pmid:26530401
|
Liu D et al. |
Inhibitory Effect of Hesperetin and Naringenin on Human UDP-Glucuronosyltransferase Enzymes: Implications for Herb-Drug Interactions. |
2016 |
Biol. Pharm. Bull. |
pmid:27904048
|
Romero GB et al. |
Simple low-cost miniaturization approach for pharmaceutical nanocrystals production. |
2016 |
Int J Pharm |
pmid:26642945
|
Nakajima VM et al. |
Biotransformation effects on anti lipogenic activity of citrus extracts. |
2016 |
Food Chem |
pmid:26675840
|
Ahmadi A et al. |
The Role of Hesperidin in Cell Signal Transduction Pathway for the Prevention or Treatment of Cancer. |
2015 |
Curr. Med. Chem. |
pmid:26502950
|
Wang W et al. |
Scavenging of Toxic Acrolein by Resveratrol and Hesperetin and Identification of Adducts. |
2015 |
J. Agric. Food Chem. |
pmid:26457480
|
Unno T et al. |
Hesperetin Modifies the Composition of Fecal Microbiota and Increases Cecal Levels of Short-Chain Fatty Acids in Rats. |
2015 |
J. Agric. Food Chem. |
pmid:26306898
|
Shen C et al. |
Intestinal absorption mechanisms of MTBH, a novel hesperetin derivative, in Caco-2 cells, and potential involvement of monocarboxylate transporter 1 and multidrug resistance protein 2. |
2015 |
Eur J Pharm Sci |
pmid:26231439
|
Iranshahi M et al. |
Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin. |
2015 |
Life Sci. |
pmid:26188593
|
Arya A et al. |
Validation of RP-HPLC Method for Simultaneous Quantification of Bicalutamide and Hesperetin in Polycaprolactone-Bicalutamide-Hesperetin-Chitosan Nanoparticles. |
2015 |
J Chromatogr Sci |
pmid:26045585
|
Parhiz H et al. |
Antioxidant and anti-inflammatory properties of the citrus flavonoids hesperidin and hesperetin: an updated review of their molecular mechanisms and experimental models. |
2015 |
Phytother Res |
pmid:25394264
|
Palit S et al. |
Hesperetin Induces Apoptosis in Breast Carcinoma by Triggering Accumulation of ROS and Activation of ASK1/JNK Pathway. |
2015 |
J. Cell. Physiol. |
pmid:25204891
|
Adan A and Baran Y |
The pleiotropic effects of fisetin and hesperetin on human acute promyelocytic leukemia cells are mediated through apoptosis, cell cycle arrest, and alterations in signaling networks. |
2015 |
Tumour Biol. |
pmid:26081618
|
Shete G et al. |
Effect of Mannitol on Nucleation and Crystal Growth of Amorphous Flavonoids: Implications on the Formation of Nanocrystalline Solid Dispersion. |
2015 |
J Pharm Sci |
pmid:26183113
|