NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neuralgia D009437 28 associated lipids
Acute Lung Injury D055371 33 associated lipids
Per page 10 20 50 | Total 23

PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Lee EJ et al. Naringin-induced p21WAF1-mediated G(1)-phase cell cycle arrest via activation of the Ras/Raf/ERK signaling pathway in vascular smooth muscle cells. 2008 Food Chem. Toxicol. pmid:18951945
Vij G et al. Modulation of antigen-induced chronic fatigue in mouse model of water immersion stress by naringin, a polyphenolic antioxidant. 2009 Fundam Clin Pharmacol pmid:19469804
Kawaguchi K et al. Suppression of inflammatory responses after onset of collagen-induced arthritis in mice by oral administration of the Citrus flavanone naringin. 2011 Immunopharmacol Immunotoxicol pmid:21480758
Luo YL et al. Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. 2013 Inflamm. Res. pmid:24085318
Jain M and Parmar HS Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. 2011 Inflamm. Res. pmid:21181230
Fuhr U et al. Grapefruit juice increases oral nimodipine bioavailability. 1998 Int J Clin Pharmacol Ther pmid:9562227
Stohs SJ et al. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. 2011 Int J Med Sci pmid:21537493
Choi JS and Han HK Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. 2005 Int J Pharm pmid:16226412
Choi JS and Shin SC Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. 2005 Int J Pharm pmid:15725561
Prota L et al. Leucine enhances aerosol performance of naringin dry powder and its activity on cystic fibrosis airway epithelial cells. 2011 Int J Pharm pmid:21459138