NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neuralgia D009437 28 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
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Authors Title Published Journal PubMed Link
Lambev I et al. [Antiexudative effect of naringin in experimental pulmonary edema and peritonitis]. 1980 Eksp Med Morfol pmid:7460808
Oki K et al. The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line. 2012 Endocrinology pmid:22798349
Liu M et al. Toxicokinetics of naringin, a putative antitussive, after 184-day repeated oral administration in rats. 2011 Environ. Toxicol. Pharmacol. pmid:21787720
Nowak-Solinska E et al. The effect of naringin on early growth and development of the spheno-occipital synchondrosis as measured by the expression of PTHrP and Sox9--an in vitro model. 2013 Eur J Orthod pmid:23172577
Sansone F et al. Physical characteristics and aerosol performance of naringin dry powders for pulmonary delivery prepared by spray-drying. 2009 Eur J Pharm Biopharm pmid:18996478
Mielczarek C Acid-base properties of selected flavonoid glycosides. 2005 Eur J Pharm Sci pmid:15911223
Runkel M et al. Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man. 1996 Eur. J. Clin. Pharmacol. pmid:8737764
Runkel M et al. The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human. 1997 Eur. J. Clin. Pharmacol. pmid:9476043
Rebello S et al. Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. 2012 Eur. J. Clin. Pharmacol. pmid:22124880
Kawaguchi K et al. Suppression of lipopolysaccharide-induced tumor necrosis factor-release and liver injury in mice by naringin. 1999 Eur. J. Pharmacol. pmid:10193661