NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mahmoud AM et al. | Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats. | 2012 Nov-Dec | J. Diabetes Complicat. | pmid:22809898 |
Yadav V et al. | Alpha-L-rhamnosidase from Aspergillus clavato-nanicus MTCC-9611 active at alkaline pH. | 2012 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:22834305 |
Xulu S and Oroma Owira PM | Naringin ameliorates atherogenic dyslipidemia but not hyperglycemia in rats with type 1 diabetes. | 2012 | J. Cardiovasc. Pharmacol. | pmid:21964158 |
Zou W et al. | Tissue distribution study of naringin in rats by liquid chromatography-tandem mass spectrometry. | 2012 | Arzneimittelforschung | pmid:22270844 |
Parmar HS et al. | DPP-IV inhibitory potential of naringin: an in silico, in vitro and in vivo study. | 2012 | Diabetes Res. Clin. Pract. | pmid:22410395 |
Luo Z et al. | Effects of pH on the ability of flavonoids to act as Pickering emulsion stabilizers. | 2012 | Colloids Surf B Biointerfaces | pmid:22197223 |
Shaik N et al. | Inhibition of Ca(2+) entry and suicidal erythrocyte death by naringin. | 2012 | Cell. Physiol. Biochem. | pmid:22854627 |
Huang W et al. | Simultaneous UPLC analysis of three major flavonoids in granule decoctions of Fructus aurantii-type formulae. | 2012 | Pharmazie | pmid:22888512 |
Gopinath K and Sudhandiran G | Naringin modulates oxidative stress and inflammation in 3-nitropropionic acid-induced neurodegeneration through the activation of nuclear factor-erythroid 2-related factor-2 signalling pathway. | 2012 | Neuroscience | pmid:22871521 |
Ni H et al. | Characterization and preparation of Aspergillus niger naringinase for debittering citrus juice. | 2012 | J. Food Sci. | pmid:22122507 |