NSC5548
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with NSC5548?
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with NSC5548
PubChem Associated disorders and diseases
What pathways are associated with NSC5548
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with NSC5548?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with NSC5548?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with NSC5548?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with NSC5548?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with NSC5548?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with NSC5548
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Liu Q et al. | Cell surface engineering of α-l-rhamnosidase for naringin hydrolysis. | 2012 | Bioresour. Technol. | pmid:22940311 |
| Uckoo RM et al. | Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques. | 2012 | J. Food Sci. | pmid:22957912 |
| Liu Y et al. | Naringin inhibits chemokine production in an LPS-induced RAW 264.7 macrophage cell line. | 2012 | Mol Med Rep | pmid:22965302 |
| Zhang J et al. | Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells. | 2012 | Food Chem | pmid:22953882 |
| Nie YC et al. | Anti-inflammatory effects of naringin in chronic pulmonary neutrophilic inflammation in cigarette smoke-exposed rats. | 2012 | J Med Food | pmid:22985397 |
| Poulaert M et al. | Grapefruit juices impair the bioaccessibility of β-carotene from orange-fleshed sweet potato but not its intestinal uptake by Caco-2 cells. | 2012 | J. Agric. Food Chem. | pmid:22221263 |
| Ikemura M et al. | Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke-prone spontaneously hypertensive rats. | 2012 | Phytother Res | pmid:22228501 |
| Wang JN et al. | Population pharmacokinetics of naringin in total flavonoids of Drynaria fortunei (Kunze) J. Sm. in Chinese women with primary osteoporosis. | 2012 | Chin J Integr Med | pmid:23239001 |
| Nunes MA et al. | High-affinity water-soluble system for efficient naringinase immobilization in polyvinyl alcohol-dimethyl sulfoxide lens-shaped particles. | 2012 | J. Mol. Recognit. | pmid:23108618 |
| Gao S et al. | Antitussive effect of naringin on experimentally induced cough in Guinea pigs. | 2011 | Planta Med. | pmid:20645246 |
| Jagetia GC and Reddy TK | Alleviation of iron induced oxidative stress by the grape fruit flavanone naringin in vitro. | 2011 | Chem. Biol. Interact. | pmid:21345335 |
| Kim SW et al. | Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. | 2011 | Biochem. Biophys. Res. Commun. | pmid:22074828 |
| Viswanatha GL et al. | Amelioration of immobilization stress-induced biochemical and behavioral alterations and mitochondrial dysfunction by naringin in mice: possible mechanism of nitric oxide modulation. | 2011 | Zhong Xi Yi Jie He Xue Bao | pmid:22088593 |
| Liu Y et al. | Naringin attenuates acute lung injury in LPS-treated mice by inhibiting NF-κB pathway. | 2011 | Int. Immunopharmacol. | pmid:21640201 |
| Bodas R et al. | Naringin and vitamin E influence the oxidative stability and lipid profile of plasma in lambs fed fish oil. | 2011 | Res. Vet. Sci. | pmid:20800247 |
| Rojas NL et al. | Purification and characterization of a novel alkaline α-L-rhamnosidase produced by Acrostalagmus luteo albus. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21221705 |
| Santos ML et al. | Modulation of the pharmacological activities of secretory phospholipase A2 from Crotalus durissus cascavella induced by naringin. | 2011 | Molecules | pmid:21245808 |
| Shirasaka Y et al. | Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. | 2011 | Drug Metab. Pharmacokinet. | pmid:21206133 |
| Jain M and Parmar HS | Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. | 2011 | Inflamm. Res. | pmid:21181230 |
| Amudha K and Pari L | Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats. | 2011 | Chem. Biol. Interact. | pmid:21600195 |