NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Reperfusion Injury D015427 65 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Precancerous Conditions D011230 48 associated lipids
Leukemia P388 D007941 43 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neuralgia D009437 28 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Cachexia D002100 21 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cough D003371 19 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Gao S et al. Antitussive effect of naringin on experimentally induced cough in Guinea pigs. 2011 Planta Med. pmid:20645246
Jagetia GC and Reddy TK Alleviation of iron induced oxidative stress by the grape fruit flavanone naringin in vitro. 2011 Chem. Biol. Interact. pmid:21345335
A Bakheet S and M Attia S Evaluation of chromosomal instability in diabetic rats treated with naringin. 2011 Oxid Med Cell Longev pmid:21941606
Gopinath K et al. Neuroprotective effect of naringin, a dietary flavonoid against 3-nitropropionic acid-induced neuronal apoptosis. 2011 Neurochem. Int. pmid:21945202
Elíades LA et al. α-L-rhamnosidase and β-D-glucosidase activities in fungal strains isolated from alkaline soils and their potential in naringin hydrolysis. 2011 J. Basic Microbiol. pmid:21952976
Dai H et al. A highly sensitive and selective sensing ECL platform for naringin based on β-Cyclodextrin functionalized carbon nanohorns. 2011 Chem. Commun. (Camb.) pmid:21975830
Leray V et al. Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats. 2011 Br. J. Nutr. pmid:22005428
Yu HY et al. Anti-platelet effects of yuzu extract and its component. 2011 Food Chem. Toxicol. pmid:22005257
Xu C et al. [Study on technology in preparation of Fructus Auranti extract]. 2011 Zhongguo Zhong Yao Za Zhi pmid:22308686
Si-Si W et al. Inhibition of TNF-α/IFN-γ induced RANTES expression in HaCaT cell by naringin. 2011 Pharm Biol pmid:21500970
Stohs SJ et al. Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. 2011 Int J Med Sci pmid:21537493
Shirasaka Y et al. Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. 2011 J Pharm Sci pmid:21520088
Puri M et al. Molecular characterization and enzymatic hydrolysis of naringin extracted from kinnow peel waste. 2011 Int. J. Biol. Macromol. pmid:20920523
Pari L and Amudha K Hepatoprotective role of naringin on nickel-induced toxicity in male Wistar rats. 2011 Eur. J. Pharmacol. pmid:20950607
Walker AL et al. Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters. 2011 Exp. Hematol. pmid:21256917
Rojas NL et al. Purification and characterization of a novel alkaline α-L-rhamnosidase produced by Acrostalagmus luteo albus. 2011 J. Ind. Microbiol. Biotechnol. pmid:21221705
Santos ML et al. Modulation of the pharmacological activities of secretory phospholipase A2 from Crotalus durissus cascavella induced by naringin. 2011 Molecules pmid:21245808
Shirasaka Y et al. Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. 2011 Drug Metab. Pharmacokinet. pmid:21206133
Jain M and Parmar HS Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. 2011 Inflamm. Res. pmid:21181230
Amudha K and Pari L Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats. 2011 Chem. Biol. Interact. pmid:21600195