NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Gao S et al. | Antitussive effect of naringin on experimentally induced cough in Guinea pigs. | 2011 | Planta Med. | pmid:20645246 |
Jagetia GC and Reddy TK | Alleviation of iron induced oxidative stress by the grape fruit flavanone naringin in vitro. | 2011 | Chem. Biol. Interact. | pmid:21345335 |
A Bakheet S and M Attia S | Evaluation of chromosomal instability in diabetic rats treated with naringin. | 2011 | Oxid Med Cell Longev | pmid:21941606 |
Gopinath K et al. | Neuroprotective effect of naringin, a dietary flavonoid against 3-nitropropionic acid-induced neuronal apoptosis. | 2011 | Neurochem. Int. | pmid:21945202 |
ElÃades LA et al. | α-L-rhamnosidase and β-D-glucosidase activities in fungal strains isolated from alkaline soils and their potential in naringin hydrolysis. | 2011 | J. Basic Microbiol. | pmid:21952976 |
Dai H et al. | A highly sensitive and selective sensing ECL platform for naringin based on β-Cyclodextrin functionalized carbon nanohorns. | 2011 | Chem. Commun. (Camb.) | pmid:21975830 |
Leray V et al. | Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats. | 2011 | Br. J. Nutr. | pmid:22005428 |
Yu HY et al. | Anti-platelet effects of yuzu extract and its component. | 2011 | Food Chem. Toxicol. | pmid:22005257 |
Xu C et al. | [Study on technology in preparation of Fructus Auranti extract]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22308686 |
Si-Si W et al. | Inhibition of TNF-α/IFN-γ induced RANTES expression in HaCaT cell by naringin. | 2011 | Pharm Biol | pmid:21500970 |
Stohs SJ et al. | Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. | 2011 | Int J Med Sci | pmid:21537493 |
Shirasaka Y et al. | Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. | 2011 | J Pharm Sci | pmid:21520088 |
Puri M et al. | Molecular characterization and enzymatic hydrolysis of naringin extracted from kinnow peel waste. | 2011 | Int. J. Biol. Macromol. | pmid:20920523 |
Pari L and Amudha K | Hepatoprotective role of naringin on nickel-induced toxicity in male Wistar rats. | 2011 | Eur. J. Pharmacol. | pmid:20950607 |
Walker AL et al. | Transcellular movement of hydroxyurea is mediated by specific solute carrier transporters. | 2011 | Exp. Hematol. | pmid:21256917 |
Rojas NL et al. | Purification and characterization of a novel alkaline α-L-rhamnosidase produced by Acrostalagmus luteo albus. | 2011 | J. Ind. Microbiol. Biotechnol. | pmid:21221705 |
Santos ML et al. | Modulation of the pharmacological activities of secretory phospholipase A2 from Crotalus durissus cascavella induced by naringin. | 2011 | Molecules | pmid:21245808 |
Shirasaka Y et al. | Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. | 2011 | Drug Metab. Pharmacokinet. | pmid:21206133 |
Jain M and Parmar HS | Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. | 2011 | Inflamm. Res. | pmid:21181230 |
Amudha K and Pari L | Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats. | 2011 | Chem. Biol. Interact. | pmid:21600195 |