NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Atherosclerosis D050197 85 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Reperfusion Injury D015427 65 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Precancerous Conditions D011230 48 associated lipids
Leukemia P388 D007941 43 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neuralgia D009437 28 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Cachexia D002100 21 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cough D003371 19 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Soria F and Ellenrieder G Thermal inactivation and product inhibition of Aspergillus terreus CECT 2663 alpha-L-rhamnosidase and their role on hydrolysis of naringin solutions. 2002 Biosci. Biotechnol. Biochem. pmid:12224626
Kanno S et al. Effects of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in P388 cells. 2003 J. Pharmacol. Sci. pmid:12832847
Seo HJ et al. Role of naringin supplement in regulation of lipid and ethanol metabolism in rats. 2003 Life Sci. pmid:12798418
Kanaze FI et al. Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations. 2003 J Pharm Biomed Anal pmid:12972089
Møller MT et al. Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes. 2003 Biochem. J. pmid:12697024
Hermans K et al. Grapefruit and tonic: a deadly combination in a patient with the long QT syndrome. 2003 Am. J. Med. pmid:12727589
Caccamese S et al. Chiral HPLC separation and CD spectra of the C-2 diastereomers of naringin in grapefruit during maturation. 2003 Chirality pmid:12923803
Jagetia GC et al. Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow. 2003 Mutagenesis pmid:12840107
Jung UJ et al. Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects. 2003 Clin Nutr pmid:14613759
Martearena MR et al. Synthesis of alkyl-alpha-L-rhamnosides by water soluble alcohols enzymatic glycosylation. 2003 Bioresour. Technol. pmid:14575952