NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kempler GM | Production of flavor compounds by microorganisms. | 1983 | Adv. Appl. Microbiol. | pmid:6650264 |
Lambev I et al. | Flavonoids with antioxidant action (naringin and rutin) and the release of mastocytic and nonmastocytic histamine. | 1980 | Acta Physiol Pharmacol Bulg | pmid:6159775 |
Robbins RC et al. | Ingestion of grapefruit lowers elevated hematocrits in human subjects. | 1988 | Int J Vitam Nutr Res | pmid:3243695 |
Ding XF | [Strains and quality of zhiqiao in Jiangxi Province]. | 1986 | Zhong Yao Tong Bao | pmid:2944652 |
Sahu BD et al. | Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: possible mechanism of nephroprotection. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24637089 |
Ozyürek M et al. | Novel oxime based flavanone, naringin-oxime: synthesis, characterization and screening for antioxidant activity. | 2014 | Chem. Biol. Interact. | pmid:24508591 |
Ahmad SF et al. | Amelioration of autoimmune arthritis by naringin through modulation of T regulatory cells and Th1/Th2 cytokines. | 2014 | Cell. Immunol. | pmid:24487035 |
Hudzenko OV and Varbanets' LD | [Substrate specificity of Cryptococcus albidus and Eupenicillium erubescens alpha-L-rhamnosidases]. | 2013 Sep-Oct | Ukr Biokhim Zh (1999) | pmid:24479319 |
Chandramohan Y and Parameswari CS | Therapeutic efficacy of naringin on cyclosporine (A) induced nephrotoxicity in rats: involvement of hemeoxygenase-1. | 2013 | Pharmacol Rep | pmid:24399730 |
Chen J et al. | Inhibition of the leptin-induced activation of the p38 MAPK pathway contributes to the protective effects of naringin against high glucose-induced injury in H9c2 cardiac cells. | 2014 | Int. J. Mol. Med. | pmid:24399619 |