NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Mahmoud AM et al. | Hesperidin and naringin attenuate hyperglycemia-mediated oxidative stress and proinflammatory cytokine production in high fat fed/streptozotocin-induced type 2 diabetic rats. | 2012 Nov-Dec | J. Diabetes Complicat. | pmid:22809898 |
Yadav V et al. | Alpha-L-rhamnosidase from Aspergillus clavato-nanicus MTCC-9611 active at alkaline pH. | 2012 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:22834305 |
Rebello S et al. | Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22124880 |
Wang D et al. | Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer's disease. | 2012 | Pharmacol. Biochem. Behav. | pmid:22741174 |
Maratha SR and Mahadevan N | Memory enhancing activity of naringin in unstressed and stressed mice: possible cholinergic and nitriergic modulation. | 2012 | Neurochem. Res. | pmid:22821418 |
Liu MH et al. | Study on impurities in naringin extracted from Citrus grandis 'tomentosa'. | 2012 | Zhong Yao Cai | pmid:22734411 |
Oki K et al. | The potassium channel, Kir3.4 participates in angiotensin II-stimulated aldosterone production by a human adrenocortical cell line. | 2012 | Endocrinology | pmid:22798349 |
Liu Y et al. | [Transdermal behavior of effective constituents in xuanbi gel plaster]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22803360 |
Nie YC et al. | Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways. | 2012 | Eur. J. Pharmacol. | pmid:22766066 |
Lassoued MA et al. | Absorption enhancement studies of clopidogrel hydrogen sulphate in rat everted gut sacs. | 2012 | J. Pharm. Pharmacol. | pmid:22420660 |