NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Soria F and Ellenrieder G | Thermal inactivation and product inhibition of Aspergillus terreus CECT 2663 alpha-L-rhamnosidase and their role on hydrolysis of naringin solutions. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224626 |
Kanno S et al. | Effects of naringin on hydrogen peroxide-induced cytotoxicity and apoptosis in P388 cells. | 2003 | J. Pharmacol. Sci. | pmid:12832847 |
Seo HJ et al. | Role of naringin supplement in regulation of lipid and ethanol metabolism in rats. | 2003 | Life Sci. | pmid:12798418 |
Kanaze FI et al. | Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations. | 2003 | J Pharm Biomed Anal | pmid:12972089 |
Møller MT et al. | Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes. | 2003 | Biochem. J. | pmid:12697024 |
Hermans K et al. | Grapefruit and tonic: a deadly combination in a patient with the long QT syndrome. | 2003 | Am. J. Med. | pmid:12727589 |
Caccamese S et al. | Chiral HPLC separation and CD spectra of the C-2 diastereomers of naringin in grapefruit during maturation. | 2003 | Chirality | pmid:12923803 |
Jagetia GC et al. | Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow. | 2003 | Mutagenesis | pmid:12840107 |
Jung UJ et al. | Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects. | 2003 | Clin Nutr | pmid:14613759 |
Martearena MR et al. | Synthesis of alkyl-alpha-L-rhamnosides by water soluble alcohols enzymatic glycosylation. | 2003 | Bioresour. Technol. | pmid:14575952 |
Giannuzzo AN et al. | Supercritical fluid extraction of naringin from the peel of Citrus paradisi. | 2003 Jul-Aug | Phytochem Anal | pmid:12892417 |
Jung UJ et al. | The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. | 2004 | J. Nutr. | pmid:15465737 |
Kubo M et al. | [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka]. | 2004 | Yakushigaku Zasshi | pmid:16025659 |
Jeon SM et al. | Antihypercholesterolemic property of naringin alters plasma and tissue lipids, cholesterol-regulating enzymes, fecal sterol and tissue morphology in rabbits. | 2004 | Clin Nutr | pmid:15380892 |
Singh D et al. | Protective effect of naringin, a bioflavonoid on ferric nitrilotriacetate-induced oxidative renal damage in rat kidney. | 2004 | Toxicology | pmid:15297014 |
Singh D et al. | Protective effect of naringin, a bioflavonoid on glycerol-induced acute renal failure in rat kidney. | 2004 | Toxicology | pmid:15297029 |
Jagetia GC et al. | Influence of naringin on ferric iron induced oxidative damage in vitro. | 2004 | Clin. Chim. Acta | pmid:15313158 |
Kanno S et al. | Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells. | 2004 | Life Sci. | pmid:15135655 |
Kim HJ et al. | Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. | 2004 | Life Sci. | pmid:14738906 |
Li X et al. | LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii. | 2004 | J Pharm Biomed Anal | pmid:14738930 |