NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Bailey DG et al. | Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics. | 1993 | Clin. Pharmacol. Ther. | pmid:8275614 |
Bailey DG et al. | Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin. | 1993 | Clin. Pharmacol. Ther. | pmid:8513655 |
Yao QS and Chiou GC | Inhibition of crystallins-induced inflammation in rabbit eyes with five phytogenic compounds. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8503279 |
Mouly P et al. | Column liquid chromatographic determination of flavanone glycosides in Citrus. Application to grapefruit and sour orange juice adulterations. | 1993 | J. Chromatogr. | pmid:8486744 |
Bailey DG et al. | Grapefruit juice and drugs. How significant is the interaction? | 1994 | Clin Pharmacokinet | pmid:8162660 |
Zhou FR and Zhang ZQ | [Quality evaluation of 3 kinds of rhizoma Drynariae]. | 1994 | Zhongguo Zhong Yao Za Zhi | pmid:7945861 |
Johnston A and Holt DW | Effect of grapefruit juice on blood cyclosporin concentration. | 1995 | Lancet | pmid:7603196 |
Gordon PB et al. | Protection by naringin and some other flavonoids of hepatocytic autophagy and endocytosis against inhibition by okadaic acid. | 1995 | J. Biol. Chem. | pmid:7890712 |
Kometani T et al. | Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8829532 |
Runkel M et al. | Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8737764 |