NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shirasaka Y et al. | Intestinal absorption of HMG-CoA reductase inhibitor pitavastatin mediated by organic anion transporting polypeptide and P-glycoprotein/multidrug resistance 1. | 2011 | Drug Metab. Pharmacokinet. | pmid:21206133 |
Jain M and Parmar HS | Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. | 2011 | Inflamm. Res. | pmid:21181230 |
Amudha K and Pari L | Beneficial role of naringin, a flavanoid on nickel induced nephrotoxicity in rats. | 2011 | Chem. Biol. Interact. | pmid:21600195 |
Gao S et al. | Antitussive effect of naringin on experimentally induced cough in Guinea pigs. | 2011 | Planta Med. | pmid:20645246 |
Rebello S et al. | Intestinal OATP1A2 inhibition as a potential mechanism for the effect of grapefruit juice on aliskiren pharmacokinetics in healthy subjects. | 2012 | Eur. J. Clin. Pharmacol. | pmid:22124880 |
Liu T et al. | Aspergillus niger DLFCC-90 rhamnoside hydrolase, a new type of flavonoid glycoside hydrolase. | 2012 | Appl. Environ. Microbiol. | pmid:22544243 |
Nie YC et al. | Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways. | 2012 | Eur. J. Pharmacol. | pmid:22766066 |
Lassoued MA et al. | Absorption enhancement studies of clopidogrel hydrogen sulphate in rat everted gut sacs. | 2012 | J. Pharm. Pharmacol. | pmid:22420660 |
Rong W et al. | Naringin treatment improves functional recovery by increasing BDNF and VEGF expression, inhibiting neuronal apoptosis after spinal cord injury. | 2012 | Neurochem. Res. | pmid:22453521 |
Kwatra D et al. | Transfected MDCK cell line with enhanced expression of CYP3A4 and P-glycoprotein as a model to study their role in drug transport and metabolism. | 2012 | Mol. Pharm. | pmid:22676443 |