NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Shirasaka Y et al. | Intestinal absorption of HMG-CoA reductase inhibitor pravastatin mediated by organic anion transporting polypeptide. | 2010 | Pharm. Res. | pmid:20686826 |
Shirasaka Y et al. | Concentration-dependent effect of naringin on intestinal absorption of beta(1)-adrenoceptor antagonist talinolol mediated by p-glycoprotein and organic anion transporting polypeptide (Oatp). | 2009 | Pharm. Res. | pmid:19002566 |
Chandramohan Y and Parameswari CS | Therapeutic efficacy of naringin on cyclosporine (A) induced nephrotoxicity in rats: involvement of hemeoxygenase-1. | 2013 | Pharmacol Rep | pmid:24399730 |
Wang D et al. | Long-term naringin consumption reverses a glucose uptake defect and improves cognitive deficits in a mouse model of Alzheimer's disease. | 2012 | Pharmacol. Biochem. Behav. | pmid:22741174 |
Singh D and Chopra K | The effect of naringin, a bioflavonoid on ischemia-reperfusion induced renal injury in rats. | 2004 | Pharmacol. Res. | pmid:15177308 |
Jang Y et al. | Naringin exhibits in vivo prokinetic activity via activation of ghrelin receptor in gastrointestinal motility dysfunction rats. | 2013 | Pharmacology | pmid:24080610 |
Huang W et al. | Simultaneous UPLC analysis of three major flavonoids in granule decoctions of Fructus aurantii-type formulae. | 2012 | Pharmazie | pmid:22888512 |
Koca U et al. | Decreasing unpalatable flavonoid components in Citrus: the effect of transformation construct. | 2009 | Physiol Plant | pmid:19656329 |
Qin XM et al. | Discrimination of three medicinal materials from the Citrus genus by HPLC fingerprint coupled with two complementary software. | 2009 Jul-Aug | Phytochem Anal | pmid:19425114 |
Giannuzzo AN et al. | Supercritical fluid extraction of naringin from the peel of Citrus paradisi. | 2003 Jul-Aug | Phytochem Anal | pmid:12892417 |