NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Body Weight D001835 333 associated lipids
Weight Gain D015430 101 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Atherosclerosis D050197 85 associated lipids
Reperfusion Injury D015427 65 associated lipids
Cystic Fibrosis D003550 65 associated lipids
Precancerous Conditions D011230 48 associated lipids
Leukemia P388 D007941 43 associated lipids
Neurotoxicity Syndromes D020258 34 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Acute Lung Injury D055371 33 associated lipids
Neuralgia D009437 28 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Cachexia D002100 21 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cough D003371 19 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Endophthalmitis D009877 12 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Kanaze FI et al. The phytochemical analysis and antioxidant activity assessment of orange peel (Citrus sinensis) cultivated in Greece-Crete indicates a new commercial source of hesperidin. 2009 Biomed. Chromatogr. pmid:18823075
Kim HJ and Choi JS Effects of naringin on the pharmacokinetics of verapamil and one of its metabolites, norverapamil, in rabbits. 2005 Biopharm Drug Dispos pmid:16013069
Lim SC and Choi JS Effects of naringin on the pharmacokinetics of intravenous paclitaxel in rats. 2006 Biopharm Drug Dispos pmid:17009338
Liu M et al. Metabolism and excretion studies of oral administered naringin, a putative antitussive, in rats and dogs. 2012 Biopharm Drug Dispos pmid:22374702
Liu Q et al. Cell surface engineering of α-l-rhamnosidase for naringin hydrolysis. 2012 Bioresour. Technol. pmid:22940311
Martearena MR et al. Synthesis of alkyl-alpha-L-rhamnosides by water soluble alcohols enzymatic glycosylation. 2003 Bioresour. Technol. pmid:14575952
Nunes MA et al. Microtiter plates versus stirred mini-bioreactors in biocatalysis: a scalable approach. 2013 Bioresour. Technol. pmid:23563437
Kometani T et al. Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. 1996 Biosci. Biotechnol. Biochem. pmid:8829532
Soria F and Ellenrieder G Thermal inactivation and product inhibition of Aspergillus terreus CECT 2663 alpha-L-rhamnosidase and their role on hydrolysis of naringin solutions. 2002 Biosci. Biotechnol. Biochem. pmid:12224626
Ichinose H et al. Characterization of an α-L-Rhamnosidase from Streptomyces avermitilis. 2013 Biosci. Biotechnol. Biochem. pmid:23291751