NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Caccamese S et al. | Chiral HPLC separation and CD spectra of the C-2 diastereomers of naringin in grapefruit during maturation. | 2003 | Chirality | pmid:12923803 |
Kanaze FI et al. | Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations. | 2003 | J Pharm Biomed Anal | pmid:12972089 |
Martearena MR et al. | Synthesis of alkyl-alpha-L-rhamnosides by water soluble alcohols enzymatic glycosylation. | 2003 | Bioresour. Technol. | pmid:14575952 |
Jung UJ et al. | Naringin supplementation lowers plasma lipids and enhances erythrocyte antioxidant enzyme activities in hypercholesterolemic subjects. | 2003 | Clin Nutr | pmid:14613759 |
Kim HJ et al. | Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. | 2004 | Life Sci. | pmid:14738906 |
Li X et al. | LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii. | 2004 | J Pharm Biomed Anal | pmid:14738930 |
Kanno S et al. | Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells. | 2004 | Life Sci. | pmid:15135655 |
Singh D and Chopra K | The effect of naringin, a bioflavonoid on ischemia-reperfusion induced renal injury in rats. | 2004 | Pharmacol. Res. | pmid:15177308 |
Singh D et al. | Protective effect of naringin, a bioflavonoid on ferric nitrilotriacetate-induced oxidative renal damage in rat kidney. | 2004 | Toxicology | pmid:15297014 |
Singh D et al. | Protective effect of naringin, a bioflavonoid on glycerol-induced acute renal failure in rat kidney. | 2004 | Toxicology | pmid:15297029 |