NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Li H et al. | Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway. | 2013 | Toxicol. Lett. | pmid:23694763 |
Chen Y et al. | Protective effects of naringin against paraquat-induced acute lung injury and pulmonary fibrosis in mice. | 2013 | Food Chem. Toxicol. | pmid:23603004 |
Zhai YK et al. | [Effects of naringin on proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23596885 |
Nunes MA et al. | Microtiter plates versus stirred mini-bioreactors in biocatalysis: a scalable approach. | 2013 | Bioresour. Technol. | pmid:23563437 |
Li N et al. | Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis. | 2013 | J Orthop Sci | pmid:23553541 |
Zhang X et al. | Investigation of the interaction of naringin palmitate with bovine serum albumin: spectroscopic analysis and molecular docking. | 2013 | PLoS ONE | pmid:23527100 |
Prakash A et al. | Naringin protects memory impairment and mitochondrial oxidative damage against aluminum-induced neurotoxicity in rats. | 2013 | Int. J. Neurosci. | pmid:23510099 |
Alam MA et al. | Naringin improves diet-induced cardiovascular dysfunction and obesity in high carbohydrate, high fat diet-fed rats. | 2013 | Nutrients | pmid:23446977 |
Miyazaki N et al. | Effects of itraconazole, dexamethasone and naringin on the pharmacokinetics of nadolol in rats. | 2013 | Drug Metab. Pharmacokinet. | pmid:23419354 |
Arnao MB et al. | An enzymatic colorimetric method for measuring naringin using 2,2'-azino-bis-(3-ethylbenzthiazoline-6-sulfonic acid)(ABTS) in the presence of peroxidase. | 1990 | Anal. Biochem. | pmid:2339789 |
Ichinose H et al. | Characterization of an α-L-Rhamnosidase from Streptomyces avermitilis. | 2013 | Biosci. Biotechnol. Biochem. | pmid:23291751 |
Chen Y et al. | Purification and characterization of a naringinase from Aspergillus aculeatus JMUdb058. | 2013 | J. Agric. Food Chem. | pmid:23289582 |
Wang JN et al. | Population pharmacokinetics of naringin in total flavonoids of Drynaria fortunei (Kunze) J. Sm. in Chinese women with primary osteoporosis. | 2012 | Chin J Integr Med | pmid:23239001 |
Nowak-Solinska E et al. | The effect of naringin on early growth and development of the spheno-occipital synchondrosis as measured by the expression of PTHrP and Sox9--an in vitro model. | 2013 | Eur J Orthod | pmid:23172577 |
Yu X et al. | Inhibiting wear particles-induced osteolysis with naringin. | 2013 | Int Orthop | pmid:23111634 |
Nunes MA et al. | High-affinity water-soluble system for efficient naringinase immobilization in polyvinyl alcohol-dimethyl sulfoxide lens-shaped particles. | 2012 | J. Mol. Recognit. | pmid:23108618 |
Nie YC et al. | Anti-inflammatory effects of naringin in chronic pulmonary neutrophilic inflammation in cigarette smoke-exposed rats. | 2012 | J Med Food | pmid:22985397 |
Liu Y et al. | Naringin inhibits chemokine production in an LPS-induced RAW 264.7 macrophage cell line. | 2012 | Mol Med Rep | pmid:22965302 |
Uckoo RM et al. | Grapefruit (Citrus paradisi Macfad) phytochemicals composition is modulated by household processing techniques. | 2012 | J. Food Sci. | pmid:22957912 |
Zhang J et al. | Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells. | 2012 | Food Chem | pmid:22953882 |