NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Bailey DG et al. | Grapefruit juice-felodipine interaction: effect of naringin and 6',7'-dihydroxybergamottin in humans. | 1998 | Clin. Pharmacol. Ther. | pmid:9757148 |
Rundén E et al. | Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism. | 1998 | J. Neurosci. | pmid:9736650 |
Fuhr U et al. | Grapefruit juice increases oral nimodipine bioavailability. | 1998 | Int J Clin Pharmacol Ther | pmid:9562227 |
Runkel M et al. | The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human. | 1997 | Eur. J. Clin. Pharmacol. | pmid:9476043 |
Manzanares P et al. | Purification and characterization of an alpha-L-rhamnosidase from Aspergillus niger. | 1997 | FEMS Microbiol. Lett. | pmid:9435109 |
Drewnowski A et al. | Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. | 1997 | Am. J. Clin. Nutr. | pmid:9250119 |
Kawaguchi K et al. | Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9028038 |
Kometani T et al. | Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8829532 |
Runkel M et al. | Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8737764 |
Bailey DG et al. | Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin. | 1993 | Clin. Pharmacol. Ther. | pmid:8513655 |