NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Cough D003371 19 associated lipids
Cachexia D002100 21 associated lipids
Endophthalmitis D009877 12 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Atherosclerosis D050197 85 associated lipids
Acute Lung Injury D055371 33 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Neuralgia D009437 28 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Zou W et al. Tissue distribution study of naringin in rats by liquid chromatography-tandem mass spectrometry. 2012 Arzneimittelforschung pmid:22270844
Catalán-Latorre A et al. In situ study of the effect of naringin, talinolol and protein-energy undernutrition on intestinal absorption of saquinavir in rats. 2011 Basic Clin. Pharmacol. Toxicol. pmid:21535410
Chen J et al. Naringin inhibits ROS-activated MAPK pathway in high glucose-induced injuries in H9c2 cardiac cells. 2014 Basic Clin. Pharmacol. Toxicol. pmid:24118820
Kumar P and Kumar A Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide. 2010 Behav. Brain Res. pmid:19716383
Kim SW et al. Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. 2011 Biochem. Biophys. Res. Commun. pmid:22074828
Samari HR et al. Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins. 2005 Biochem. J. pmid:15461583
Møller MT et al. Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes. 2003 Biochem. J. pmid:12697024
Cariño-Cortés R et al. Effect of naringin on the DNA damage induced by daunorubicin in mouse hepatocytes and cardiocytes. 2010 Biol. Pharm. Bull. pmid:20410608
Golechha M et al. Naringin protects against kainic acid-induced status epilepticus in rats: evidence for an antioxidant, anti-inflammatory and neuroprotective intervention. 2011 Biol. Pharm. Bull. pmid:21372385
Wong RW and Rabie AB Effect of naringin collagen graft on bone formation. 2006 Biomaterials pmid:16310246