NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Cough D003371 19 associated lipids
Cachexia D002100 21 associated lipids
Endophthalmitis D009877 12 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Atherosclerosis D050197 85 associated lipids
Acute Lung Injury D055371 33 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Neuralgia D009437 28 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Soria F and Ellenrieder G Thermal inactivation and product inhibition of Aspergillus terreus CECT 2663 alpha-L-rhamnosidase and their role on hydrolysis of naringin solutions. 2002 Biosci. Biotechnol. Biochem. pmid:12224626
Ichinose H et al. Characterization of an α-L-Rhamnosidase from Streptomyces avermitilis. 2013 Biosci. Biotechnol. Biochem. pmid:23291751
Tramice A et al. Direct enzymatic glucosylation of naringin in grapefruit juice by alpha-D-glucosidase from the marine mollusc Aplysia fasciata. 2008 Biotechnol J pmid:18098121
Sharma AK et al. Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. 2011 Br. J. Nutr. pmid:21736771
Leray V et al. Effect of citrus polyphenol- and curcumin-supplemented diet on inflammatory state in obese cats. 2011 Br. J. Nutr. pmid:22005428
Pang WY et al. Naringin improves bone properties in ovariectomized mice and exerts oestrogen-like activities in rat osteoblast-like (UMR-106) cells. 2010 Br. J. Pharmacol. pmid:20397301
Yow TT et al. Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. 2011 Br. J. Pharmacol. pmid:21391982
Kim DI et al. Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression. 2008 Carcinogenesis pmid:18296682
Vanamala J et al. Suppression of colon carcinogenesis by bioactive compounds in grapefruit. 2006 Carcinogenesis pmid:16387741
Russo A et al. Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors. 2000 Cell Biol. Toxicol. pmid:10917564