NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

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Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Weight Gain D015430 101 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

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Authors Title Published Journal PubMed Link
Mello LD et al. Electrochemical and spectroscopic characterization of the interaction between DNA and Cu(II)-naringin complex. 2007 J Pharm Biomed Anal pmid:17881180
Pereira RM et al. Synthesis and characterization of a metal complex containing naringin and Cu, and its antioxidant, antimicrobial, antiinflammatory and tumor cell cytotoxicity. 2007 Molecules pmid:17909491
Rajadurai M and Prince PS Preventive effect of naringin on cardiac mitochondrial enzymes during isoproterenol-induced myocardial infarction in rats: a transmission electron microscopic study. 2007 J. Biochem. Mol. Toxicol. pmid:17994577
Go YH et al. Functional characteristics of cyclodextrin glucanotransferase from alkalophilic Bacillus sp. BL-31 highly specific for intermolecular transglycosylation of bioflavonoids. 2007 J. Microbiol. Biotechnol. pmid:18062236
Tramice A et al. Direct enzymatic glucosylation of naringin in grapefruit juice by alpha-D-glucosidase from the marine mollusc Aplysia fasciata. 2008 Biotechnol J pmid:18098121
Tsui VW et al. The inhibitory effects of naringin on the growth of periodontal pathogens in vitro. 2008 Phytother Res pmid:18167053
Kim DI et al. Requirement for Ras/Raf/ERK pathway in naringin-induced G1-cell-cycle arrest via p21WAF1 expression. 2008 Carcinogenesis pmid:18296682
Zhang LH et al. [Optimal extraction of Dingxiang jiangqi granules]. 2007 Zhongguo Zhong Yao Za Zhi pmid:18309666
Punithavathi VR et al. Combined treatment with naringin and vitamin C ameliorates streptozotocin-induced diabetes in male Wistar rats. 2008 J Appl Toxicol pmid:18344197
Wu JB et al. Naringin-induced bone morphogenetic protein-2 expression via PI3K, Akt, c-Fos/c-Jun and AP-1 pathway in osteoblasts. 2008 Eur. J. Pharmacol. pmid:18495116