NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

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Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Weight Gain D015430 101 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

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Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Johnston A and Holt DW Effect of grapefruit juice on blood cyclosporin concentration. 1995 Lancet pmid:7603196
Elinbaum S et al. Production of Aspergillus terreus alpha-L-rhamnosidase by solid state fermentation. 2002 Lett. Appl. Microbiol. pmid:11849496
Scaroni E et al. Hydrolytic properties of crude alpha-L-rhamnosidases produced by several wild strains of mesophilic fungi. 2002 Lett. Appl. Microbiol. pmid:12028430
Aggarwal A et al. Nitric oxide mechanism in the protective effect of naringin against post-stroke depression (PSD) in mice. 2010 Life Sci. pmid:20433854
Jagetia GC and Reddy TK Modulation of radiation-induced alteration in the antioxidant status of mice by naringin. 2005 Life Sci. pmid:15936352
Kanno S et al. Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. 2006 Life Sci. pmid:16137700
Jeon SM et al. Antioxidative activity of naringin and lovastatin in high cholesterol-fed rabbits. 2001 Life Sci. pmid:11720089
Seo HJ et al. Role of naringin supplement in regulation of lipid and ethanol metabolism in rats. 2003 Life Sci. pmid:12798418
Kanno S et al. Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells. 2004 Life Sci. pmid:15135655
Kim HJ et al. Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. 2004 Life Sci. pmid:14738906