MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Weight Gain | D015430 | 101 associated lipids |
Body Weight | D001835 | 333 associated lipids |
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
---|
We collected disease MeSH terms mapped to the references associated with NSC5548
MeSH term | MeSH ID | Detail |
---|---|---|
Hypercholesterolemia | D006937 | 91 associated lipids |
Weight Gain | D015430 | 101 associated lipids |
Body Weight | D001835 | 333 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
---|
Function | Cross reference | Weighted score | Related literatures |
---|
Lipid concept | Cross reference | Weighted score | Related literatures |
---|
Gene | Cross reference | Weighted score | Related literatures |
---|
There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
---|---|---|---|---|
Caccamese S et al. | Chiral HPLC separation and CD spectra of the C-2 diastereomers of naringin in grapefruit during maturation. | 2003 | Chirality | pmid:12923803 |
Jagetia GC et al. | Naringin, a citrus flavonone, protects against radiation-induced chromosome damage in mouse bone marrow. | 2003 | Mutagenesis | pmid:12840107 |
Elinbaum S et al. | Production of Aspergillus terreus alpha-L-rhamnosidase by solid state fermentation. | 2002 | Lett. Appl. Microbiol. | pmid:11849496 |
Jeon SM et al. | Comparison of antioxidant effects of naringin and probucol in cholesterol-fed rabbits. | 2002 | Clin. Chim. Acta | pmid:11814474 |
Jagetia GC and Reddy TK | The grapefruit flavanone naringin protects against the radiation-induced genomic instability in the mice bone marrow: a micronucleus study. | 2002 | Mutat. Res. | pmid:12160890 |
Larsen AK et al. | Naringin-sensitive phosphorylation of plectin, a cytoskeletal cross-linking protein, in isolated rat hepatocytes. | 2002 | J. Biol. Chem. | pmid:12095991 |
Ohtani M et al. | [Effect of grapefruit pulp on the pharmacokinetics of the dihydropyridine calcium antagonists nifedipine and nisoldipine]. | 2002 | Yakugaku Zasshi | pmid:12040751 |
Scaroni E et al. | Hydrolytic properties of crude alpha-L-rhamnosidases produced by several wild strains of mesophilic fungi. | 2002 | Lett. Appl. Microbiol. | pmid:12028430 |
Tsai TH | Determination of naringin in rat blood, brain, liver, and bile using microdialysis and its interaction with cyclosporin a, a p-glycoprotein modulator. | 2002 | J. Agric. Food Chem. | pmid:12405759 |
Soria F and Ellenrieder G | Thermal inactivation and product inhibition of Aspergillus terreus CECT 2663 alpha-L-rhamnosidase and their role on hydrolysis of naringin solutions. | 2002 | Biosci. Biotechnol. Biochem. | pmid:12224626 |