NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

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Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Weight Gain D015430 101 associated lipids
Body Weight D001835 333 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

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Authors Title Published Journal PubMed Link
Muller GW et al. Carboxylic acid replacement structure-activity relationships in suosan type sweeteners. A sweet taste antagonist. 1. 1992 J. Med. Chem. pmid:1588556
Mielczarek C Acid-base properties of selected flavonoid glycosides. 2005 Eur J Pharm Sci pmid:15911223
Jagetia GC and Reddy TK Modulation of radiation-induced alteration in the antioxidant status of mice by naringin. 2005 Life Sci. pmid:15936352
Huang ZF et al. [Study on quality control of effective fraction in qixue bingzhi decoction]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16011278
Kim HJ and Choi JS Effects of naringin on the pharmacokinetics of verapamil and one of its metabolites, norverapamil, in rabbits. 2005 Biopharm Drug Dispos pmid:16013069
Desiderio C et al. Analysis of flavanone-7-O-glycosides in citrus juices by short-end capillary electrochromatography. 2005 J Chromatogr A pmid:16013605
Kubo M et al. [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka]. 2004 Yakushigaku Zasshi pmid:16025659
Kanno S et al. Inhibitory effect of naringin on lipopolysaccharide (LPS)-induced endotoxin shock in mice and nitric oxide production in RAW 264.7 macrophages. 2006 Life Sci. pmid:16137700
Tourniaire F et al. Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells. 2005 Mol Nutr Food Res pmid:16189799
Choi JS and Han HK Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. 2005 Int J Pharm pmid:16226412