NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

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Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Hypercholesterolemia D006937 91 associated lipids
Weight Gain D015430 101 associated lipids
Body Weight D001835 333 associated lipids
Per page 10 20 50 | Total 23

PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

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Authors Title Published Journal PubMed Link
Kanaze FI et al. A validated solid-phase extraction HPLC method for the simultaneous determination of the citrus flavanone aglycones hesperetin and naringenin in urine. 2004 J Pharm Biomed Anal pmid:15351063
Singh D and Chopra K The effect of naringin, a bioflavonoid on ischemia-reperfusion induced renal injury in rats. 2004 Pharmacol. Res. pmid:15177308
Kanno S et al. Effects of naringin on cytosine arabinoside (Ara-C)-induced cytotoxicity and apoptosis in P388 cells. 2004 Life Sci. pmid:15135655
Kim HJ et al. Naringin alters the cholesterol biosynthesis and antioxidant enzyme activities in LDL receptor-knockout mice under cholesterol fed condition. 2004 Life Sci. pmid:14738906
Li X et al. LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii. 2004 J Pharm Biomed Anal pmid:14738930
Gorinstein S et al. Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation. 2005 J. Agric. Food Chem. pmid:15826081
Choi JS and Han HK Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. 2005 Int J Pharm pmid:16226412
Samari HR et al. Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins. 2005 Biochem. J. pmid:15461583
Desiderio C et al. Analysis of flavanone-7-O-glycosides in citrus juices by short-end capillary electrochromatography. 2005 J Chromatogr A pmid:16013605
Tourniaire F et al. Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells. 2005 Mol Nutr Food Res pmid:16189799