MeSH term | MeSH ID | Detail |
---|---|---|
Atherosclerosis | D050197 | 85 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with NSC5548
MeSH term | MeSH ID | Detail |
---|---|---|
Atherosclerosis | D050197 | 85 associated lipids |
Acute Lung Injury | D055371 | 33 associated lipids |
Acute Kidney Injury | D058186 | 34 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Rani N et al. | Regulation of heat shock proteins 27 and 70, p-Akt/p-eNOS and MAPKs by Naringin Dampens myocardial injury and dysfunction in vivo after ischemia/reperfusion. | 2013 | PLoS ONE | pmid:24324809 |
Sequetto PL et al. | Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis. | 2014 | Food Chem. Toxicol. | pmid:24296135 |
Li S et al. | Content changes of bitter compounds in 'Guoqing No.1' Satsuma mandarin (Citrus unshiu Marc.) during fruit development of consecutive 3 seasons. | 2014 | Food Chem | pmid:24128570 |
Chen J et al. | Naringin inhibits ROS-activated MAPK pathway in high glucose-induced injuries in H9c2 cardiac cells. | 2014 | Basic Clin. Pharmacol. Toxicol. | pmid:24118820 |
Luo YL et al. | Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. | 2013 | Inflamm. Res. | pmid:24085318 |
Jang Y et al. | Naringin exhibits in vivo prokinetic activity via activation of ghrelin receptor in gastrointestinal motility dysfunction rats. | 2013 | Pharmacology | pmid:24080610 |
Ni H et al. | Development and evaluation of an HPLC method for accurate determinations of enzyme activities of naringinase complex. | 2013 | J. Agric. Food Chem. | pmid:24070201 |
Li P et al. | Acute and 13 weeks subchronic toxicological evaluation of naringin in Sprague-Dawley rats. | 2013 | Food Chem. Toxicol. | pmid:23871784 |
Zhao J et al. | Pharmacokinetic and pharmacodynamic studies of four major phytochemical components of Da-Cheng-Qi decoction to treat acute pancreatitis. | 2013 | J. Pharmacol. Sci. | pmid:23739595 |
Huang H et al. | Naringin inhibits high glucose-induced cardiomyocyte apoptosis by attenuating mitochondrial dysfunction and modulating the activation of the p38 signaling pathway. | 2013 | Int. J. Mol. Med. | pmid:23732220 |