| MeSH term | MeSH ID | Detail |
|---|---|---|
| Neurotoxicity Syndromes | D020258 | 34 associated lipids |
| Uveitis, Posterior | D015866 | 5 associated lipids |
| Chromosomal Instability | D043171 | 5 associated lipids |
NSC5548
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with NSC5548?
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with NSC5548
PubChem Associated disorders and diseases
What pathways are associated with NSC5548
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with NSC5548?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with NSC5548?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with NSC5548?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with NSC5548?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with NSC5548?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with NSC5548
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ding P et al. | [Effects of naringin on proliferation, differentiation and matrix mineralization of MC3T3-E1 cells]. | 2009 | Zhongguo Zhong Yao Za Zhi | pmid:19873788 |
| Qu QL et al. | [Identification of jizhi syrup using HPLC fingerprint]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:17608218 |
| Zhang LH et al. | [Optimal extraction of Dingxiang jiangqi granules]. | 2007 | Zhongguo Zhong Yao Za Zhi | pmid:18309666 |
| Huang ZF et al. | [Study on quality control of effective fraction in qixue bingzhi decoction]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011278 |
| Zhou YH and Zou HJ | [Studies on chemical constituents of naringin]. | 1993 | Zhongguo Zhong Yao Za Zhi | pmid:8011085 |
| Liu ZL et al. | [Determination of three chemical components in Fructus aurantii immaturus]. | 2006 | Zhongguo Zhong Yao Za Zhi | pmid:17087081 |
| Zhou FR and Zhang ZQ | [Quality evaluation of 3 kinds of rhizoma Drynariae]. | 1994 | Zhongguo Zhong Yao Za Zhi | pmid:7945861 |
| Wang Y and Li J | [Qualitative identification and quantitative determination of naringin in rhizoma Drynariae by TLC]. | 1998 | Zhongguo Zhong Yao Za Zhi | pmid:11599350 |
| Xu C et al. | [Study on technology in preparation of Fructus Auranti extract]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:22308686 |
| Liu Y et al. | [Transdermal behavior of effective constituents in xuanbi gel plaster]. | 2012 | Zhongguo Zhong Yao Za Zhi | pmid:22803360 |
| Zhai YK et al. | [Effects of naringin on proliferation, differentiation and maturation of rat calvarial osteoblasts in vitro]. | 2013 | Zhongguo Zhong Yao Za Zhi | pmid:23596885 |
| Xu D and Cheng K | [Determination of liquiritin, naringin, hesperidin and glycyrrhizic acid in extractive of Wendan formula by RP-HPLC]. | 2011 | Zhongguo Zhong Yao Za Zhi | pmid:21473151 |
| Wang J et al. | [Simultaneous determination of chlorogenic acid, cryptochlorogenic acid, caffeic acid, naringin, hesperidin and linarin in xiao'erjinning oral liquid by an HPLC method]. | 2010 | Zhongguo Zhong Yao Za Zhi | pmid:20862961 |
| Yao QS and Chiou GC | Inhibition of crystallins-induced inflammation in rabbit eyes with five phytogenic compounds. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8503279 |
| Ding XF | [Strains and quality of zhiqiao in Jiangxi Province]. | 1986 | Zhong Yao Tong Bao | pmid:2944652 |
| Liu MH et al. | Study on impurities in naringin extracted from Citrus grandis 'tomentosa'. | 2012 | Zhong Yao Cai | pmid:22734411 |
| Hu Y et al. | [Pharmacognostical identification of one Rhizoma Drynariae habitually used species from Yunnan]. | 2000 | Zhong Yao Cai | pmid:12575083 |
| Xiao M et al. | [Determination of naringin and synephrine in fructus aurantii from different habitats by HPLC]. | 2000 | Zhong Yao Cai | pmid:12575153 |
| Li J et al. | [A review of the study on Drynaria fortunei]. | 1999 | Zhong Yao Cai | pmid:12903628 |
| Chen JC et al. | [Anti-inflammatory effects and quantitative study of the combinations of active ingredients of Painong powder in mice]. | 2009 | Zhong Xi Yi Jie He Xue Bao | pmid:19583936 |
| Viswanatha GL et al. | Amelioration of immobilization stress-induced biochemical and behavioral alterations and mitochondrial dysfunction by naringin in mice: possible mechanism of nitric oxide modulation. | 2011 | Zhong Xi Yi Jie He Xue Bao | pmid:22088593 |
| Hu QY et al. | [Traditional Chinese medicine Drynaria fortunei J. Smith naringin promotes proliferation and differentiation of human periodontal ligament cells]. | 2010 | Zhejiang Da Xue Xue Bao Yi Xue Ban | pmid:20175240 |
| Ali MM et al. | Modulation of anticancer drug-induced P-glycoprotein expression by naringin. | 2009 Jan-Feb | Z. Naturforsch., C, J. Biosci. | pmid:19323275 |
| Wilhelmi G and Maier R | [Test of potential antiarthritic drugs on spontaneous arthritis of mice]. | 1983 Jul-Aug | Z Rheumatol | pmid:6689102 |
| Kubo M et al. | [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka]. | 2004 | Yakushigaku Zasshi | pmid:16025659 |
| Luo R et al. | Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies. | 2009 | Yakugaku Zasshi | pmid:19952535 |
| Li K et al. | Determination of liquiritin, naringin, hesperidin, thymol, imperatorin, honokiol, isoimperatorin, and magnolol in the traditional Chinese medicinal preparation Huoxiang-zhengqi liquid using high-performance liquid chromatography. | 2006 | Yakugaku Zasshi | pmid:17077620 |
| Ohtani M et al. | [Effect of grapefruit pulp on the pharmacokinetics of the dihydropyridine calcium antagonists nifedipine and nisoldipine]. | 2002 | Yakugaku Zasshi | pmid:12040751 |
| Gong HL et al. | Effect of severe acute pancreatitis on pharmacokinetics of Da-Cheng-Qi Decoction components. | 2009 | World J. Gastroenterol. | pmid:20014465 |
| Hudzenko OV and Varbanets' LD | [Substrate specificity of Cryptococcus albidus and Eupenicillium erubescens alpha-L-rhamnosidases]. | 2013 Sep-Oct | Ukr Biokhim Zh (1999) | pmid:24479319 |
| Berven G et al. | Effects of the diarrhetic shellfish toxin, okadaic acid, on cytoskeletal elements, viability and functionality of rat liver and intestinal cells. | 2001 Feb-Mar | Toxicon | pmid:10978754 |
| Rajadurai M and Prince PS | Preventive effect of naringin on isoproterenol-induced cardiotoxicity in Wistar rats: an in vivo and in vitro study. | 2007 | Toxicology | pmid:17289242 |
| Rajadurai M and Stanely Mainzen Prince P | Preventive effect of naringin on lipid peroxides and antioxidants in isoproterenol-induced cardiotoxicity in Wistar rats: biochemical and histopathological evidences. | 2006 | Toxicology | pmid:17084010 |
| Rajadurai M and Stanely Mainzen Prince P | Preventive effect of naringin on cardiac markers, electrocardiographic patterns and lysosomal hydrolases in normal and isoproterenol-induced myocardial infarction in Wistar rats. | 2007 | Toxicology | pmid:17188415 |
| Singh D et al. | Protective effect of naringin, a bioflavonoid on ferric nitrilotriacetate-induced oxidative renal damage in rat kidney. | 2004 | Toxicology | pmid:15297014 |
| Singh D et al. | Protective effect of naringin, a bioflavonoid on glycerol-induced acute renal failure in rat kidney. | 2004 | Toxicology | pmid:15297029 |
| Møller MT et al. | Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation. | 2004 | Toxicol. Sci. | pmid:15342961 |
| Li H et al. | Naringin inhibits growth potential of human triple-negative breast cancer cells by targeting β-catenin signaling pathway. | 2013 | Toxicol. Lett. | pmid:23694763 |
| Sahu BD et al. | Naringin ameliorates gentamicin-induced nephrotoxicity and associated mitochondrial dysfunction, apoptosis and inflammation in rats: possible mechanism of nephroprotection. | 2014 | Toxicol. Appl. Pharmacol. | pmid:24637089 |
| Yilmaz D et al. | Influence of naringin on cadmium-induced genomic damage in human lymphocytes in vitro. | 2012 | Toxicol Ind Health | pmid:21636685 |
| Chen L et al. | [Specific depletion of naringin from Si-Ni-San, a traditional Chinese prescription, by an immunoaffinity chromatography]. | 2006 | Se Pu | pmid:16929840 |
| Li XL et al. | [Determination of hesperidin and naringin in Fructus Aurantii Immaturus and Fructus Aurantii by reversed-phase high performance liquid chromatography]. | 2002 | Se Pu | pmid:12683015 |
| KEENAN GL | The occurrence of crystalline naringin on grapefruit rind. | 1946 | Science | pmid:20995510 |
| Harapu CD et al. | [Flavonoids--bioactive compounds in fruits juice]. | 2010 Oct-Dec | Rev Med Chir Soc Med Nat Iasi | pmid:21500482 |
| Bodas R et al. | Naringin and vitamin E influence the oxidative stability and lipid profile of plasma in lambs fed fish oil. | 2011 | Res. Vet. Sci. | pmid:20800247 |
| Yadav V et al. | Alpha-L-rhamnosidase from Aspergillus clavato-nanicus MTCC-9611 active at alkaline pH. | 2012 May-Jun | Prikl. Biokhim. Mikrobiol. | pmid:22834305 |
| Zhang X et al. | Investigation of the interaction of naringin palmitate with bovine serum albumin: spectroscopic analysis and molecular docking. | 2013 | PLoS ONE | pmid:23527100 |
| Rani N et al. | Regulation of heat shock proteins 27 and 70, p-Akt/p-eNOS and MAPKs by Naringin Dampens myocardial injury and dysfunction in vivo after ischemia/reperfusion. | 2013 | PLoS ONE | pmid:24324809 |
| Gao S et al. | Antitussive effect of naringin on experimentally induced cough in Guinea pigs. | 2011 | Planta Med. | pmid:20645246 |
| Rajadurai M and Prince PS | Naringin ameliorates mitochondrial lipid peroxides, antioxidants and lipids in isoproterenol-induced myocardial infarction in Wistar rats. | 2009 | Phytother Res | pmid:18844325 |