NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
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Authors Title Published Journal PubMed Link
Kim HJ and Choi JS Effects of naringin on the pharmacokinetics of verapamil and one of its metabolites, norverapamil, in rabbits. 2005 Biopharm Drug Dispos pmid:16013069
Gorinstein S et al. Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation. 2005 J. Agric. Food Chem. pmid:15826081
Choi JS and Han HK Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. 2005 Int J Pharm pmid:16226412
Samari HR et al. Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins. 2005 Biochem. J. pmid:15461583
Mielczarek C Acid-base properties of selected flavonoid glycosides. 2005 Eur J Pharm Sci pmid:15911223
Jagetia GC and Reddy TK Modulation of radiation-induced alteration in the antioxidant status of mice by naringin. 2005 Life Sci. pmid:15936352
Huang ZF et al. [Study on quality control of effective fraction in qixue bingzhi decoction]. 2005 Zhongguo Zhong Yao Za Zhi pmid:16011278
Tourniaire F et al. Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells. 2005 Mol Nutr Food Res pmid:16189799
Jung UJ et al. The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. 2004 J. Nutr. pmid:15465737
Kubo M et al. [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka]. 2004 Yakushigaku Zasshi pmid:16025659