MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Uveitis, Posterior | D015866 | 5 associated lipids |
Chromosomal Instability | D043171 | 5 associated lipids |
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Disease | Cross reference | Weighted score | Related literature |
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We collected disease MeSH terms mapped to the references associated with NSC5548
MeSH term | MeSH ID | Detail |
---|---|---|
Neurotoxicity Syndromes | D020258 | 34 associated lipids |
Uveitis, Posterior | D015866 | 5 associated lipids |
Chromosomal Instability | D043171 | 5 associated lipids |
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
Location | Cross reference | Weighted score | Related literatures |
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Function | Cross reference | Weighted score | Related literatures |
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Lipid concept | Cross reference | Weighted score | Related literatures |
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Gene | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Kim HJ and Choi JS | Effects of naringin on the pharmacokinetics of verapamil and one of its metabolites, norverapamil, in rabbits. | 2005 | Biopharm Drug Dispos | pmid:16013069 |
Gorinstein S et al. | Changes in plasma lipid and antioxidant activity in rats as a result of naringin and red grapefruit supplementation. | 2005 | J. Agric. Food Chem. | pmid:15826081 |
Choi JS and Han HK | Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. | 2005 | Int J Pharm | pmid:16226412 |
Samari HR et al. | Stimulation of hepatocytic AMP-activated protein kinase by okadaic acid and other autophagy-suppressive toxins. | 2005 | Biochem. J. | pmid:15461583 |
Mielczarek C | Acid-base properties of selected flavonoid glycosides. | 2005 | Eur J Pharm Sci | pmid:15911223 |
Jagetia GC and Reddy TK | Modulation of radiation-induced alteration in the antioxidant status of mice by naringin. | 2005 | Life Sci. | pmid:15936352 |
Huang ZF et al. | [Study on quality control of effective fraction in qixue bingzhi decoction]. | 2005 | Zhongguo Zhong Yao Za Zhi | pmid:16011278 |
Tourniaire F et al. | Molecular mechanisms of the naringin low uptake by intestinal Caco-2 cells. | 2005 | Mol Nutr Food Res | pmid:16189799 |
Jung UJ et al. | The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice. | 2004 | J. Nutr. | pmid:15465737 |
Kubo M et al. | [History and therapeutic evaluation of Citrus hassaku HORT. Tanaka]. | 2004 | Yakushigaku Zasshi | pmid:16025659 |