NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Neurotoxicity Syndromes D020258 34 associated lipids
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
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Authors Title Published Journal PubMed Link
Kim SW et al. Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. 2011 Biochem. Biophys. Res. Commun. pmid:22074828
Viswanatha GL et al. Amelioration of immobilization stress-induced biochemical and behavioral alterations and mitochondrial dysfunction by naringin in mice: possible mechanism of nitric oxide modulation. 2011 Zhong Xi Yi Jie He Xue Bao pmid:22088593
Sharma AK et al. Up-regulation of PPARγ, heat shock protein-27 and -72 by naringin attenuates insulin resistance, β-cell dysfunction, hepatic steatosis and kidney damage in a rat model of type 2 diabetes. 2011 Br. J. Nutr. pmid:21736771
Bodas R et al. Naringin and vitamin E influence the oxidative stability and lipid profile of plasma in lambs fed fish oil. 2011 Res. Vet. Sci. pmid:20800247
Soria F et al. α-L-rhamnosidase of Aspergillus terreus immobilized on ferromagnetic supports. 2012 Appl. Microbiol. Biotechnol. pmid:21779843
Zhang J et al. Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells. 2012 Food Chem pmid:22953882
Nie YC et al. Anti-inflammatory effects of naringin in chronic pulmonary neutrophilic inflammation in cigarette smoke-exposed rats. 2012 J Med Food pmid:22985397
Poulaert M et al. Grapefruit juices impair the bioaccessibility of β-carotene from orange-fleshed sweet potato but not its intestinal uptake by Caco-2 cells. 2012 J. Agric. Food Chem. pmid:22221263
Yilmaz D et al. Influence of naringin on cadmium-induced genomic damage in human lymphocytes in vitro. 2012 Toxicol Ind Health pmid:21636685
Chanet A et al. Naringin, the major grapefruit flavonoid, specifically affects atherosclerosis development in diet-induced hypercholesterolemia in mice. 2012 J. Nutr. Biochem. pmid:21684135