NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neuralgia D009437 28 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
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Authors Title Published Journal PubMed Link
Itoh K et al. Antiallergic activity of unripe Citrus hassaku fruits extract and its flavanone glycosides on chemical substance-induced dermatitis in mice. 2009 J Nat Med pmid:19603253
Li N et al. Naringin promotes osteoblast differentiation and effectively reverses ovariectomy-associated osteoporosis. 2013 J Orthop Sci pmid:23553541
Uchiyama N et al. HPLC separation of naringin, neohesperidin and their C-2 epimers in commercial samples and herbal medicines. 2008 J Pharm Biomed Anal pmid:17532169
Zhou DY et al. Identification of O-diglycosyl flavanones in Fructus aurantii by liquid chromatography with electrospray ionization and collision-induced dissociation mass spectrometry. 2006 J Pharm Biomed Anal pmid:16837161
Mello LD et al. Electrochemical and spectroscopic characterization of the interaction between DNA and Cu(II)-naringin complex. 2007 J Pharm Biomed Anal pmid:17881180
Kanaze FI et al. Simultaneous reversed-phase high-performance liquid chromatographic method for the determination of diosmin, hesperidin and naringin in different citrus fruit juices and pharmaceutical formulations. 2003 J Pharm Biomed Anal pmid:12972089
Kanaze FI et al. A validated solid-phase extraction HPLC method for the simultaneous determination of the citrus flavanone aglycones hesperetin and naringenin in urine. 2004 J Pharm Biomed Anal pmid:15351063
Li X et al. LC-MS/MS determination of naringin, hesperidin and neohesperidin in rat serum after orally administrating the decoction of Bulpleurum falcatum L. and Fractus aurantii. 2004 J Pharm Biomed Anal pmid:14738930
Shirasaka Y et al. Differential effect of grapefruit juice on intestinal absorption of statins due to inhibition of organic anion transporting polypeptide and/or P-glycoprotein. 2011 J Pharm Sci pmid:21520088
Ishii K et al. Mass spectrometric identification and high-performance liquid chromatographic determination of a flavonoid glycoside naringin in human urine. 2000 J. Agric. Food Chem. pmid:10637051