NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Uveitis, Posterior D015866 5 associated lipids
Chromosomal Instability D043171 5 associated lipids
Endophthalmitis D009877 12 associated lipids
Pancreatitis, Acute Necrotizing D019283 18 associated lipids
Cough D003371 19 associated lipids
Dermatitis, Allergic Contact D017449 20 associated lipids
Cachexia D002100 21 associated lipids
Carcinoma 256, Walker D002279 22 associated lipids
Neuralgia D009437 28 associated lipids
Micronuclei, Chromosome-Defective D048629 33 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
Per page 10 20 50 100 | Total 283
Authors Title Published Journal PubMed Link
Zhang P et al. Effects of naringin on the proliferation and osteogenic differentiation of human bone mesenchymal stem cell. 2009 Eur. J. Pharmacol. pmid:19326565
Beekwilder J et al. Characterization of Rhamnosidases from Lactobacillus plantarum and Lactobacillus acidophilus. 2009 Appl. Environ. Microbiol. pmid:19346347
Laska M et al. Gustatory responsiveness to six bitter tastants in three species of nonhuman primates. 2009 J. Chem. Ecol. pmid:19399556
Qin XM et al. Discrimination of three medicinal materials from the Citrus genus by HPLC fingerprint coupled with two complementary software. 2009 Jul-Aug Phytochem Anal pmid:19425114
Vij G et al. Modulation of antigen-induced chronic fatigue in mouse model of water immersion stress by naringin, a polyphenolic antioxidant. 2009 Fundam Clin Pharmacol pmid:19469804
Iqbal MF and Zhu WY Bioactivation of flavonoid diglycosides by chicken cecal bacteria. 2009 FEMS Microbiol. Lett. pmid:19473248
Little TJ et al. Sweetness and bitterness taste of meals per se does not mediate gastric emptying in humans. 2009 Am. J. Physiol. Regul. Integr. Comp. Physiol. pmid:19535679
Gaur V et al. Protective effect of naringin against ischemic reperfusion cerebral injury: possible neurobehavioral, biochemical and cellular alterations in rat brain. 2009 Eur. J. Pharmacol. pmid:19577560
Chen JC et al. [Anti-inflammatory effects and quantitative study of the combinations of active ingredients of Painong powder in mice]. 2009 Zhong Xi Yi Jie He Xue Bao pmid:19583936
Itoh K et al. Antiallergic activity of unripe Citrus hassaku fruits extract and its flavanone glycosides on chemical substance-induced dermatitis in mice. 2009 J Nat Med pmid:19603253
Koca U et al. Decreasing unpalatable flavonoid components in Citrus: the effect of transformation construct. 2009 Physiol Plant pmid:19656329
Kumar P and Kumar A Protective effect of hesperidin and naringin against 3-nitropropionic acid induced Huntington's like symptoms in rats: possible role of nitric oxide. 2010 Behav. Brain Res. pmid:19716383
Shirasaka Y et al. Species difference in the effect of grapefruit juice on intestinal absorption of talinolol between human and rat. 2010 J. Pharmacol. Exp. Ther. pmid:19779132
Zhou X et al. Promotion of bone formation by naringin in a titanium particle-induced diabetic murine calvarial osteolysis model. 2010 J. Orthop. Res. pmid:19824055
Ding P et al. [Effects of naringin on proliferation, differentiation and matrix mineralization of MC3T3-E1 cells]. 2009 Zhongguo Zhong Yao Za Zhi pmid:19873788
Caccamese S and Chillemi R Racemization at C-2 of naringin in pummelo (Citrus grandis) with increasing maturity determined by chiral high-performance liquid chromatography. 2010 J Chromatogr A pmid:19913235
Kumar A et al. Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by D-galactose in mice. 2010 Food Chem. Toxicol. pmid:19941926
Luo R et al. Determination of sophoricoside in rat plasma by HPLC and its application to pharmacokinetic studies. 2009 Yakugaku Zasshi pmid:19952535
Gong HL et al. Effect of severe acute pancreatitis on pharmacokinetics of Da-Cheng-Qi Decoction components. 2009 World J. Gastroenterol. pmid:20014465
Xiong Y et al. [Naringin inhibits monocyte adhesion to high glucose-induced human umbilical vein endothelial cells]. 2010 Nan Fang Yi Ke Da Xue Xue Bao pmid:20159712