| MeSH term | MeSH ID | Detail |
|---|---|---|
| Body Weight | D001835 | 333 associated lipids |
| Cachexia | D002100 | 21 associated lipids |
| Carcinoma 256, Walker | D002279 | 22 associated lipids |
| Cough | D003371 | 19 associated lipids |
| Cystic Fibrosis | D003550 | 65 associated lipids |
| Diabetes Mellitus, Experimental | D003921 | 85 associated lipids |
| Diabetes Mellitus, Type 2 | D003924 | 87 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Leukemia P388 | D007941 | 43 associated lipids |
| Neuralgia | D009437 | 28 associated lipids |
NSC5548
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with NSC5548?
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with NSC5548
PubChem Associated disorders and diseases
What pathways are associated with NSC5548
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with NSC5548?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with NSC5548?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with NSC5548?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with NSC5548?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with NSC5548?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with NSC5548
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|---|---|---|---|---|
| Li S et al. | Content changes of bitter compounds in 'Guoqing No.1' Satsuma mandarin (Citrus unshiu Marc.) during fruit development of consecutive 3 seasons. | 2014 | Food Chem | pmid:24128570 |
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| Rani N et al. | Regulation of heat shock proteins 27 and 70, p-Akt/p-eNOS and MAPKs by Naringin Dampens myocardial injury and dysfunction in vivo after ischemia/reperfusion. | 2013 | PLoS ONE | pmid:24324809 |
| Chen J et al. | Inhibition of the leptin-induced activation of the p38 MAPK pathway contributes to the protective effects of naringin against high glucose-induced injury in H9c2 cardiac cells. | 2014 | Int. J. Mol. Med. | pmid:24399619 |
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| Bailey DG et al. | Grapefruit juice and drugs. How significant is the interaction? | 1994 | Clin Pharmacokinet | pmid:8162660 |
| Bailey DG et al. | Effect of grapefruit juice and naringin on nisoldipine pharmacokinetics. | 1993 | Clin. Pharmacol. Ther. | pmid:8275614 |
| Mouly P et al. | Column liquid chromatographic determination of flavanone glycosides in Citrus. Application to grapefruit and sour orange juice adulterations. | 1993 | J. Chromatogr. | pmid:8486744 |
| Yao QS and Chiou GC | Inhibition of crystallins-induced inflammation in rabbit eyes with five phytogenic compounds. | 1993 | Zhongguo Yao Li Xue Bao | pmid:8503279 |
| Bailey DG et al. | Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin. | 1993 | Clin. Pharmacol. Ther. | pmid:8513655 |
| Runkel M et al. | Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man. | 1996 | Eur. J. Clin. Pharmacol. | pmid:8737764 |
| Kometani T et al. | Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. | 1996 | Biosci. Biotechnol. Biochem. | pmid:8829532 |
| Kawaguchi K et al. | Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas. | 1997 | Biosci. Biotechnol. Biochem. | pmid:9028038 |
| Drewnowski A et al. | Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. | 1997 | Am. J. Clin. Nutr. | pmid:9250119 |
| Manzanares P et al. | Purification and characterization of an alpha-L-rhamnosidase from Aspergillus niger. | 1997 | FEMS Microbiol. Lett. | pmid:9435109 |
| Runkel M et al. | The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human. | 1997 | Eur. J. Clin. Pharmacol. | pmid:9476043 |
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| Rundén E et al. | Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism. | 1998 | J. Neurosci. | pmid:9736650 |
| Bailey DG et al. | Grapefruit juice-felodipine interaction: effect of naringin and 6',7'-dihydroxybergamottin in humans. | 1998 | Clin. Pharmacol. Ther. | pmid:9757148 |