NSC5548
NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
Cross Reference
Introduction
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with NSC5548?
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
| Disease | Cross reference | Weighted score | Related literature |
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with NSC5548
PubChem Associated disorders and diseases
What pathways are associated with NSC5548
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with NSC5548?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
| Location | Cross reference | Weighted score | Related literatures |
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What functions are associated with NSC5548?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
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What lipids are associated with NSC5548?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
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What genes are associated with NSC5548?
Related references are published most in these journals:
| Gene | Cross reference | Weighted score | Related literatures |
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What common seen animal models are associated with NSC5548?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with NSC5548
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Ramesh N et al. | Phytochemical and antimicrobial studies on Drynaria quercifolia. | 2001 | Fitoterapia | pmid:11731121 |
| Kandhare AD et al. | Neuroprotective effect of naringin by modulation of endogenous biomarkers in streptozotocin induced painful diabetic neuropathy. | 2012 | Fitoterapia | pmid:22343014 |
| Zhang J et al. | Purification of naringin and neohesperidin from Huyou (Citrus changshanensis) fruit and their effects on glucose consumption in human HepG2 cells. | 2012 | Food Chem | pmid:22953882 |
| Li S et al. | Content changes of bitter compounds in 'Guoqing No.1' Satsuma mandarin (Citrus unshiu Marc.) during fruit development of consecutive 3 seasons. | 2014 | Food Chem | pmid:24128570 |
| Yu HY et al. | Anti-platelet effects of yuzu extract and its component. | 2011 | Food Chem. Toxicol. | pmid:22005257 |
| Ramesh E and Alshatwi AA | Naringin induces death receptor and mitochondria-mediated apoptosis in human cervical cancer (SiHa) cells. | 2013 | Food Chem. Toxicol. | pmid:22847135 |
| Chen Y et al. | Protective effects of naringin against paraquat-induced acute lung injury and pulmonary fibrosis in mice. | 2013 | Food Chem. Toxicol. | pmid:23603004 |
| Li P et al. | Acute and 13 weeks subchronic toxicological evaluation of naringin in Sprague-Dawley rats. | 2013 | Food Chem. Toxicol. | pmid:23871784 |
| Kumar A et al. | Naringin alleviates cognitive impairment, mitochondrial dysfunction and oxidative stress induced by D-galactose in mice. | 2010 | Food Chem. Toxicol. | pmid:19941926 |
| Lee EJ et al. | Naringin-induced p21WAF1-mediated G(1)-phase cell cycle arrest via activation of the Ras/Raf/ERK signaling pathway in vascular smooth muscle cells. | 2008 | Food Chem. Toxicol. | pmid:18951945 |