NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.
To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.
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We collected disease MeSH terms mapped to the references associated with NSC5548
There are no associated biomedical information in the current reference collection.
Associated locations are in red color. Not associated locations are in black.
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Lipid concept | Cross reference | Weighted score | Related literatures |
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There are no associated biomedical information in the current reference collection.
Authors | Title | Published | Journal | PubMed Link |
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Sequetto PL et al. | Naringin accelerates the regression of pre-neoplastic lesions and the colorectal structural reorganization in a murine model of chemical carcinogenesis. | 2014 | Food Chem. Toxicol. | pmid:24296135 |
Vij G et al. | Modulation of antigen-induced chronic fatigue in mouse model of water immersion stress by naringin, a polyphenolic antioxidant. | 2009 | Fundam Clin Pharmacol | pmid:19469804 |
Kawaguchi K et al. | Suppression of inflammatory responses after onset of collagen-induced arthritis in mice by oral administration of the Citrus flavanone naringin. | 2011 | Immunopharmacol Immunotoxicol | pmid:21480758 |
Luo YL et al. | Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. | 2013 | Inflamm. Res. | pmid:24085318 |
Jain M and Parmar HS | Evaluation of antioxidative and anti-inflammatory potential of hesperidin and naringin on the rat air pouch model of inflammation. | 2011 | Inflamm. Res. | pmid:21181230 |
Fuhr U et al. | Grapefruit juice increases oral nimodipine bioavailability. | 1998 | Int J Clin Pharmacol Ther | pmid:9562227 |
Stohs SJ et al. | Effects of p-synephrine alone and in combination with selected bioflavonoids on resting metabolism, blood pressure, heart rate and self-reported mood changes. | 2011 | Int J Med Sci | pmid:21537493 |
Choi JS and Han HK | Enhanced oral exposure of diltiazem by the concomitant use of naringin in rats. | 2005 | Int J Pharm | pmid:16226412 |
Choi JS and Shin SC | Enhanced paclitaxel bioavailability after oral coadministration of paclitaxel prodrug with naringin to rats. | 2005 | Int J Pharm | pmid:15725561 |
Prota L et al. | Leucine enhances aerosol performance of naringin dry powder and its activity on cystic fibrosis airway epithelial cells. | 2011 | Int J Pharm | pmid:21459138 |