NSC5548

NSC5548 is a lipid of Polyketides (PK) class. Nsc5548 is associated with abnormalities such as Diabetes Mellitus, Non-Insulin-Dependent, Hyperglycemia, Coronary Arteriosclerosis, Liver diseases and Pulmonary Edema. The involved functions are known as Increased Sensitivy, Taste Perception, Cell Death, Phosphorylation and Signal Transduction. Nsc5548 often locates in Oral region, Cytoskeleton, Hepatic, Blood and Mouse Bone Marrow. The associated genes with NSC5548 are CA2 gene, P4HTM gene, FPGT gene, glycyl-L-phenylalanine and glycylphenylalanine. The related lipids are butyrate, Lipid Peroxides, blood lipid, Sterols and Total cholesterol.

Cross Reference

Introduction

To understand associated biological information of NSC5548, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with NSC5548?

NSC5548 is suspected in Hyperglycemia, Osteoporosis, Diabetes Mellitus, Non-Insulin-Dependent, Coronary Arteriosclerosis, Liver diseases, Pulmonary Edema and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with NSC5548

MeSH term MeSH ID Detail
Reperfusion Injury D015427 65 associated lipids
Diabetes Mellitus, Type 2 D003924 87 associated lipids
Diabetes Mellitus, Experimental D003921 85 associated lipids
Body Weight D001835 333 associated lipids
Precancerous Conditions D011230 48 associated lipids
Acute Kidney Injury D058186 34 associated lipids
Weight Gain D015430 101 associated lipids
Leukemia P388 D007941 43 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Cystic Fibrosis D003550 65 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with NSC5548

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with NSC5548?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with NSC5548?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with NSC5548?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with NSC5548?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with NSC5548?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with NSC5548

Download all related citations
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Authors Title Published Journal PubMed Link
Bailey DG et al. Grapefruit juice-felodipine interaction: effect of naringin and 6',7'-dihydroxybergamottin in humans. 1998 Clin. Pharmacol. Ther. pmid:9757148
Rundén E et al. Regional selective neuronal degeneration after protein phosphatase inhibition in hippocampal slice cultures: evidence for a MAP kinase-dependent mechanism. 1998 J. Neurosci. pmid:9736650
Fuhr U et al. Grapefruit juice increases oral nimodipine bioavailability. 1998 Int J Clin Pharmacol Ther pmid:9562227
Runkel M et al. The character of inhibition of the metabolism of 1,2-benzopyrone (coumarin) by grapefruit juice in human. 1997 Eur. J. Clin. Pharmacol. pmid:9476043
Manzanares P et al. Purification and characterization of an alpha-L-rhamnosidase from Aspergillus niger. 1997 FEMS Microbiol. Lett. pmid:9435109
Drewnowski A et al. Taste responses to naringin, a flavonoid, and the acceptance of grapefruit juice are related to genetic sensitivity to 6-n-propylthiouracil. 1997 Am. J. Clin. Nutr. pmid:9250119
Kawaguchi K et al. Hesperidin as an inhibitor of lipases from porcine pancreas and Pseudomonas. 1997 Biosci. Biotechnol. Biochem. pmid:9028038
Kometani T et al. Synthesis of neohesperidin glycosides and naringin glycosides by cyclodextrin glucanotransferase from an alkalophilic Bacillus species. 1996 Biosci. Biotechnol. Biochem. pmid:8829532
Runkel M et al. Metabolic and analytical interactions of grapefruit juice and 1,2-benzopyrone (coumarin) in man. 1996 Eur. J. Clin. Pharmacol. pmid:8737764
Bailey DG et al. Grapefruit juice--felodipine interaction: mechanism, predictability, and effect of naringin. 1993 Clin. Pharmacol. Ther. pmid:8513655