14r,15s-epetre

14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.

Cross Reference

Introduction

To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.

What diseases are associated with 14r,15s-epetre?

14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.

Related references are mostly published in these journals:

Disease Cross reference Weighted score Related literature
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Possible diseases from mapped MeSH terms on references

We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre

MeSH term MeSH ID Detail
Hypertension D006973 115 associated lipids
Insulin Resistance D007333 99 associated lipids
Hypercholesterolemia D006937 91 associated lipids
Brain Ischemia D002545 89 associated lipids
Liver Cirrhosis D008103 67 associated lipids
Diabetic Nephropathies D003928 39 associated lipids
Hyperemia D006940 25 associated lipids
Pre-Eclampsia D011225 16 associated lipids
Hypertrophy D006984 16 associated lipids
Lung Injury D055370 14 associated lipids
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PubChem Associated disorders and diseases

What pathways are associated with 14r,15s-epetre

There are no associated biomedical information in the current reference collection.

PubChem Biomolecular Interactions and Pathways

Link to PubChem Biomolecular Interactions and Pathways

What cellular locations are associated with 14r,15s-epetre?

Related references are published most in these journals:

Location Cross reference Weighted score Related literatures
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What functions are associated with 14r,15s-epetre?


Related references are published most in these journals:

Function Cross reference Weighted score Related literatures

What lipids are associated with 14r,15s-epetre?

Related references are published most in these journals:

Lipid concept Cross reference Weighted score Related literatures
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What genes are associated with 14r,15s-epetre?

Related references are published most in these journals:


Gene Cross reference Weighted score Related literatures

What common seen animal models are associated with 14r,15s-epetre?

There are no associated biomedical information in the current reference collection.

NCBI Entrez Crosslinks

All references with 14r,15s-epetre

Download all related citations
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Authors Title Published Journal PubMed Link
Yang T et al. The role of 14,15-dihydroxyeicosatrienoic acid levels in inflammation and its relationship to lipoproteins. 2013 Lipids Health Dis pmid:24148690
Townsley MI et al. Impact of epoxyeicosatrienoic acids in lung ischemia-reperfusion injury. 2010 Microcirculation pmid:20163540
Chen J et al. Mitogenic activity and signaling mechanism of 2-(14,15- epoxyeicosatrienoyl)glycerol, a novel cytochrome p450 arachidonate metabolite. 2007 Mol. Cell. Biol. pmid:17283047
Zeldin DC et al. CYP2J subfamily P450s in the lung: expression, localization, and potential functional significance. 1996 Mol. Pharmacol. pmid:8913342
Wang X et al. CYP2J2-derived epoxyeicosatrienoic acids suppress endoplasmic reticulum stress in heart failure. 2014 Mol. Pharmacol. pmid:24145329
Yu Z et al. Increased CYP2J expression and epoxyeicosatrienoic acid formation in spontaneously hypertensive rat kidney. 2000 Mol. Pharmacol. pmid:10779386
Planagumà A et al. Lovastatin decreases acute mucosal inflammation via 15-epi-lipoxin A4. 2010 Mucosal Immunol pmid:20130564
Li P et al. Epoxyeicosatrienoic acids enhance embryonic haematopoiesis and adult marrow engraftment. 2015 Nature pmid:26201599
Siler DA et al. Protective role of p450 epoxyeicosanoids in subarachnoid hemorrhage. 2015 Neurocrit Care pmid:25231529
Terashvili M et al. The protective effect of astrocyte-derived 14,15-epoxyeicosatrienoic acid on hydrogen peroxide-induced cell injury in astrocyte-dopaminergic neuronal cell line co-culture. 2012 Neuroscience pmid:22863680