| MeSH term | MeSH ID | Detail |
|---|---|---|
| Hypertension | D006973 | 115 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Lung Injury | D055370 | 14 associated lipids |
14r,15s-epetre
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14r,15s-epetre?
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Prostaglandins Other Lipid Mediat. (1)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
PubChem Associated disorders and diseases
What pathways are associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14r,15s-epetre?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Hypertension (1)
- Insect Biochem. Mol. Biol. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14r,15s-epetre?
Related references are published most in these journals:
- Hypertension (1)
- Prostaglandins Other Lipid Mediat. (1)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14r,15s-epetre?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14r,15s-epetre
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Sarkar P et al. | Differential effect of amyloid β on the cytochrome P450 epoxygenase activity in rat brain. | 2011 | Neuroscience | pmid:21843605 |
| Tréluyer JM et al. | Ontogenesis of CYP2C-dependent arachidonic acid metabolism in the human liver: relationship with sudden infant death syndrome. | 2000 | Pediatr. Res. | pmid:10813596 |
| Smith HE et al. | Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. | 2008 | Pharmacogenet. Genomics | pmid:18769365 |
| Gauthier KM et al. | 14,15-EET analogs: characterization of structural requirements for agonist and antagonist activity in bovine coronary arteries. | 2004 | Pharmacol. Res. | pmid:15026029 |
| Sporková A et al. | Vasodilatory responses of renal interlobular arteries to epoxyeicosatrienoic acids analog are not enhanced in Ren-2 transgenic hypertensive rats: evidence against a role of direct vascular effects of epoxyeicosatrienoic acids in progression of experimental heart failure. | 2017 | Physiol Res | pmid:27782740 |
| El-Sikhry HE et al. | Novel Roles of Epoxyeicosanoids in Regulating Cardiac Mitochondria. | 2016 | PLoS ONE | pmid:27494529 |
| Jiang JX et al. | EETs Attenuate Ox-LDL-Induced LTB4 Production and Activity by Inhibiting p38 MAPK Phosphorylation and 5-LO/BLT1 Receptor Expression in Rat Pulmonary Arterial Endothelial Cells. | 2015 | PLoS ONE | pmid:26035589 |
| Eid S et al. | 20-HETE and EETs in diabetic nephropathy: a novel mechanistic pathway. | 2013 | PLoS ONE | pmid:23936373 |
| Ballou LR et al. | Formation of cis-14,15-oxido-5,8,11-icosatrienoic acid from phosphatidylinositol in human platelets. | 1987 | Proc. Natl. Acad. Sci. U.S.A. | pmid:3118357 |
| Catella F et al. | Endogenous biosynthesis of arachidonic acid epoxides in humans: increased formation in pregnancy-induced hypertension. | 1990 | Proc. Natl. Acad. Sci. U.S.A. | pmid:2198572 |