| MeSH term | MeSH ID | Detail |
|---|---|---|
| Coronary Occlusion | D054059 | 4 associated lipids |
| Lung Injury | D055370 | 14 associated lipids |
| Pre-Eclampsia | D011225 | 16 associated lipids |
| Hypertrophy | D006984 | 16 associated lipids |
| Hyperemia | D006940 | 25 associated lipids |
| Diabetic Nephropathies | D003928 | 39 associated lipids |
| Liver Cirrhosis | D008103 | 67 associated lipids |
| Brain Ischemia | D002545 | 89 associated lipids |
| Hypercholesterolemia | D006937 | 91 associated lipids |
| Insulin Resistance | D007333 | 99 associated lipids |
| Hypertension | D006973 | 115 associated lipids |
14r,15s-epetre
14r,15s-epetre is a lipid of Fatty Acyls (FA) class. 14r,15s-epetre is associated with abnormalities such as Heart failure, Chronic Obstructive Airway Disease, Pneumonia and Fatty Liver. The involved functions are known as chromophore, Stereochemistry, Cell Respiration, cell transformation and oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen. 14r,15s-epetre often locates in Lambda, Cardiovascular system, Blood, Body tissue and Protoplasm. The associated genes with 14r,15s-epetre are CCL2 gene, Cytokine Gene, CYP2C18 gene, CYP2C19 gene and TEK gene. The related lipids are Palmitates.
Cross Reference
Introduction
To understand associated biological information of 14r,15s-epetre, we collected biological information of abnormalities, associated pathways, cellular/molecular locations, biological functions, related genes/proteins, lipids and common seen animal/experimental models with organized paragraphs from literatures.
What diseases are associated with 14r,15s-epetre?
14r,15s-epetre is suspected in Heart failure, Chronic Obstructive Airway Disease, Pneumonia, Fatty Liver and other diseases in descending order of the highest number of associated sentences.
Related references are mostly published in these journals:
- Prostaglandins Other Lipid Mediat. (1)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Am. J. Physiol. Lung Cell Mol. Physiol. (1)
| Disease | Cross reference | Weighted score | Related literature |
|---|
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Possible diseases from mapped MeSH terms on references
We collected disease MeSH terms mapped to the references associated with 14r,15s-epetre
PubChem Associated disorders and diseases
What pathways are associated with 14r,15s-epetre
There are no associated biomedical information in the current reference collection.
PubChem Biomolecular Interactions and Pathways
Link to PubChem Biomolecular Interactions and PathwaysWhat cellular locations are associated with 14r,15s-epetre?
Visualization in cellular structure
Associated locations are in red color. Not associated locations are in black.
Related references are published most in these journals:
- Am. J. Physiol. Lung Cell Mol. Physiol. (2)
- Hypertension (1)
- Insect Biochem. Mol. Biol. (1)
- Others (2)
| Location | Cross reference | Weighted score | Related literatures |
|---|
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What functions are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Function | Cross reference | Weighted score | Related literatures |
|---|
What lipids are associated with 14r,15s-epetre?
Related references are published most in these journals:
| Lipid concept | Cross reference | Weighted score | Related literatures |
|---|
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What genes are associated with 14r,15s-epetre?
Related references are published most in these journals:
- Hypertension (1)
- Prostaglandins Other Lipid Mediat. (1)
- Am. J. Physiol. Endocrinol. Metab. (1)
- Others (1)
| Gene | Cross reference | Weighted score | Related literatures |
|---|
What common seen animal models are associated with 14r,15s-epetre?
There are no associated biomedical information in the current reference collection.
NCBI Entrez Crosslinks
All references with 14r,15s-epetre
Download all related citations| Authors | Title | Published | Journal | PubMed Link |
|---|---|---|---|---|
| Wang XL et al. | Inhibition of ATP binding to the carboxyl terminus of Kir6.2 by epoxyeicosatrienoic acids. | 2006 | Biochim. Biophys. Acta | pmid:16904368 |
| Wei S et al. | Chiral resolution of the epoxyeicosatrienoic acids, arachidonic acid epoxygenase metabolites. | 2006 | Anal. Biochem. | pmid:16480681 |
| Morin C and Rousseau E | Effects of 5-oxo-ETE and 14,15-EET on reactivity and Ca2+ sensitivity in guinea pig bronchi. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17164130 |
| Jiang JG et al. | Regulation of endothelial nitric-oxide synthase activity through phosphorylation in response to epoxyeicosatrienoic acids. | 2007 | Prostaglandins Other Lipid Mediat. | pmid:17164144 |
| Morin C et al. | Epoxyeicosatrienoic acid relaxing effects involve Ca2+-activated K+ channel activation and CPI-17 dephosphorylation in human bronchi. | 2007 | Am. J. Respir. Cell Mol. Biol. | pmid:17237191 |
| Gross GJ et al. | Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts. | 2007 | J. Mol. Cell. Cardiol. | pmid:17217955 |
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| Koerner IP et al. | Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury. | 2007 | J. Neurosci. | pmid:17460077 |
| Yang W et al. | Characterization of 14,15-epoxyeicosatrienoyl-sulfonamides as 14,15-epoxyeicosatrienoic acid agonists: use for studies of metabolism and ligand binding. | 2007 | J. Pharmacol. Exp. Ther. | pmid:17327488 |
| Motoki A et al. | Soluble epoxide hydrolase inhibition and gene deletion are protective against myocardial ischemia-reperfusion injury in vivo. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18835921 |
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| Smith HE et al. | Role of cytochrome P450 2C8 and 2J2 genotypes in calcineurin inhibitor-induced chronic kidney disease. | 2008 | Pharmacogenet. Genomics | pmid:18769365 |
| Snider NT et al. | The endocannabinoid anandamide is a substrate for the human polymorphic cytochrome P450 2D6. | 2008 | J. Pharmacol. Exp. Ther. | pmid:18698000 |
| Morin C et al. | CPI-17 silencing-reduced responsiveness in control and TNF-alpha-treated human bronchi. | 2008 | Am. J. Respir. Cell Mol. Biol. | pmid:18757304 |
| Morin C et al. | EET displays anti-inflammatory effects in TNF-alpha stimulated human bronchi: putative role of CPI-17. | 2008 | Am. J. Respir. Cell Mol. Biol. | pmid:17872494 |
| Michaelis UR et al. | Role of cytochrome P450 2C epoxygenases in hypoxia-induced cell migration and angiogenesis in retinal endothelial cells. | 2008 | Invest. Ophthalmol. Vis. Sci. | pmid:18326754 |
| Ghosh S et al. | Oral delivery of 1,3-dicyclohexylurea nanosuspension enhances exposure and lowers blood pressure in hypertensive rats. | 2008 | Basic Clin. Pharmacol. Toxicol. | pmid:18312493 |
| Gross GJ et al. | Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart. | 2008 | Am. J. Physiol. Heart Circ. Physiol. | pmid:18441205 |
| Cheranov SY et al. | An essential role for SRC-activated STAT-3 in 14,15-EET-induced VEGF expression and angiogenesis. | 2008 | Blood | pmid:18408167 |
| Chen Y et al. | 20-125Iodo-14,15-epoxyeicosa-5(Z)-enoic acid: a high-affinity radioligand used to characterize the epoxyeicosatrienoic acid antagonist binding site. | 2009 | J. Pharmacol. Exp. Ther. | pmid:19762546 |